Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

300 candidates match the current filter; 10 are shown per page (page 3 of 30). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA04G336710
TK1151: TkA04G336710;TkA04G336720
OH-1004: LXL04_003623
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:89563505-89564709
-
GO:0008299
TkAUNG088930
TK1151: TkAUNG088930;TkA01G185090;TkA05G084790
OH-1004: LXL04_004202
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:129071293-129073164
+
GO:0016740
TkA01G174920
TK1151: TkA01G174920
OH-1004: LXL04_004281
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:131685419-131688990
+
GO:0016114
TkA01G040610
TK1151: TkA01G040610
OH-1004: LXL04_004327
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:132670302-132671969
+
GO:0016114
LXL04_004546
TK1151: -
OH-1004: LXL04_004546
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:139807081-139808251
+
GO:0016740
TkA01G119700
TK1151: TkA01G119700
OH-1004: LXL04_004711
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-Prot CM104799.1:144307202-144308805
+
GO:0016114
TkA01G115710
TK1151: TkA01G115710;TkA01G506900
OH-1004: LXL04_004752
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:145355300-145356759
+
GO:0016740
TkA01G109940
TK1151: TkA01G109940
OH-1004: LXL04_004801
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:147053619-147054697
+
GO:0016114
TkAUNG005740
TK1151: TkAUNG005740;TkA01G098770
OH-1004: LXL04_004894
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:149723616-149724740
+
GO:0016740
TkAUNG016690
TK1151: TkAUNG016690
OH-1004: LXL04_005063
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:153994783-153996398
-
GO:0016114

TkA04G336710

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G336710;TkA04G336720
LocationCM104799.1:89563505-89564709 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkAUNG088930

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkAUNG088930;TkA01G185090;TkA05G084790
LocationCM104799.1:129071293-129073164 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA01G174920

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G174920
LocationCM104799.1:131685419-131688990 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkA01G040610

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G040610
LocationCM104799.1:132670302-132671969 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

LXL04_004546

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104799.1:139807081-139808251 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA01G119700

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G119700
LocationCM104799.1:144307202-144308805 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidenceGO:0016114

TkA01G115710

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G115710;TkA01G506900
LocationCM104799.1:145355300-145356759 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA01G109940

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G109940
LocationCM104799.1:147053619-147054697 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkAUNG005740

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkAUNG005740;TkA01G098770
LocationCM104799.1:149723616-149724740 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkAUNG016690

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkAUNG016690
LocationCM104799.1:153994783-153996398 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.