橡胶生物合成专题

围绕 MVA/MEP、IPP/DMAPP、异戊二烯供体、CPT/CPTL、REF/SRPP、乳胶/根相关和萜类代谢，集中展示候选基因、证据等级、跨模块支持与下载入口。

本专题基于当前 GFF/GO/KEGG/同源注释预计算候选集合，并联动表达、蛋白组、亚细胞定位、Pfam、Swiss-Prot、PPI、共表达和 TFBS 等证据。所有结果为候选证据，不等同于实验证实的橡胶合成调控机制。

当前数据库收录 5523 条候选记录、4979 个候选基因和 8 个通路步骤；主显示以 TK1151 参考为中心，OH-1004/LXL04 参考仍可直接查询和跳转。

示例 TkA01G624900 LXL04_000258

下载当前筛选候选基因 TSV

跨物种研究参考

此处的 9 条参考基因与橡胶草自身候选记录分开统计。它们来自巴西橡胶树、银胶菊、近缘蒲公英和杜仲的已发表实验、组学或序列资源；同源性或外源功能不等同于橡胶草中的直接验证。

1. 选择参照物种点击下方物种卡或使用筛选框，聚焦同一物种的参考基因和材料背景。

2. 查看证据类型优先查看“证据与边界”列：直接实验、组学关联和序列资源的可解释范围不同。

3. 核查原始来源每条记录的 DOI、论文或公共数据库入口均可点击；可下载当前筛选结果用于进一步比对。

杜仲记录仅作为反式聚异戊二烯（杜仲胶）对照，不计入天然顺式橡胶候选和通路卡片数量。

9银胶菊点击查看 · 4 个来源 · cis-1,4-polyisoprene

下载当前跨物种参考 TSV

物种与材料	参考基因/序列 ID	通路步骤	证据与边界	来源
银胶菊Parthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems	`PaCBP`MF688938;ATD87120CPTL	CPT/CPTL银胶菊CPT复合体辅助亚基	A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Helper-subunit evidence must retain the assay context.	10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule
银胶菊Parthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems	`PaCPT1`MF688933;ATD87115CPT	CPT/CPTL与PaCBP形成顺式异戊二烯基转移酶复合物	A_direct_experiment PaCPT1与PaCBP在异源和体外体系中形成有活性的顺式异戊二烯基转移酶复合物。 Assay-dependent external evidence; not in-plant rubber-yield proof.	10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule
银胶菊Parthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems	`PaCPT2`MF688936;ATD87118CPT	CPT/CPTL与PaCBP形成顺式异戊二烯基转移酶复合物	A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Do not equate short-chain in-vitro activity with in-plant rubber yield.	10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule
银胶菊Parthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems	`PaCPT3`MF688934;ATD87116CPT	CPT/CPTL与PaCBP形成顺式异戊二烯基转移酶复合物	A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Do not equate short-chain in-vitro activity with in-plant rubber yield.	10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule
银胶菊Parthenium argentatumcis-1,4-polyisopreneAOS RNAi and overexpression plants	`AOS1`X78166.2CYP74	乳胶/根相关影响橡胶含量与橡胶转移酶活性的调控候选	A_direct_genetic_experiment AOS下调与橡胶含量和橡胶转移酶活性升高相关。 RNAi specificity limitation remains; do not infer a single-gene universal mechanism.	10.3389/fpls.2019.00760Silencing of allene oxide synthase in guayule increases rubber content and rubber transferase activity
银胶菊Parthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions	`PaCBP`PaTc_149493CPTL	CPT/CPTL干旱组学中的CBP转录本参考	B_omics_association PaCBP在田间水分处理茎皮转录组中被报道。 Association only; transcript abundance is not direct proof of rubber yield.	10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions
银胶菊Parthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions	`PaCPT1`PaTc_044561CPT	CPT/CPTL干旱组学中的CPT1转录本参考	B_omics_association PaCPT1在田间水分处理茎皮转录组中被报道。 Association only; transcript abundance is not direct proof of rubber yield.	10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions
银胶菊Parthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions	`PaSRPP1`PaTc_109994SRPP	REF/SRPP 橡胶颗粒干旱组学中的SRPP1转录本参考	B_omics_association 表达关联不能直接作为橡胶产量因果证据。转录本丰度不是橡胶产量的直接证明。	10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions
银胶菊Parthenium argentatumcis-1,4-polyisopreneSRPP1 promoter reporter assay	`PaSRPP1 promoter`PV754023.1SRPP	REF/SRPP 橡胶颗粒SRPP1启动子调控参考	A_promoter_experiment Promoter sequence is regulatory reference evidence, not a complete gene-model crosswalk. Promoter record is not a complete SRPP1 gene model.	10.1186/s13104-025-07448-0Functional characterization of the guayule SRPP1 promoter

银胶菊 · PaCBP

序列 IDMF688938;ATD87120

步骤CPT/CPTL · CPTL

证据PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary.

边界Helper-subunit evidence must retain the assay context.

来源10.3389/fpls.2019.00165

银胶菊 · PaCPT1

序列 IDMF688933;ATD87115

步骤CPT/CPTL · CPT

证据PaCPT1与PaCBP在异源和体外体系中形成有活性的顺式异戊二烯基转移酶复合物。

边界Assay-dependent external evidence; not in-plant rubber-yield proof.

来源10.3389/fpls.2019.00165

银胶菊 · PaCPT2

序列 IDMF688936;ATD87118

步骤CPT/CPTL · CPT

证据PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary.

边界Do not equate short-chain in-vitro activity with in-plant rubber yield.

来源10.3389/fpls.2019.00165

银胶菊 · PaCPT3

序列 IDMF688934;ATD87116

步骤CPT/CPTL · CPT

证据PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary.

边界Do not equate short-chain in-vitro activity with in-plant rubber yield.

来源10.3389/fpls.2019.00165

银胶菊 · AOS1

序列 IDX78166.2

步骤乳胶/根相关 · CYP74

证据AOS下调与橡胶含量和橡胶转移酶活性升高相关。

边界RNAi specificity limitation remains; do not infer a single-gene universal mechanism.

来源10.3389/fpls.2019.00760

银胶菊 · PaCBP

序列 IDPaTc_149493

步骤CPT/CPTL · CPTL

证据PaCBP在田间水分处理茎皮转录组中被报道。

边界Association only; transcript abundance is not direct proof of rubber yield.

来源10.1038/s41598-021-01026-7

银胶菊 · PaCPT1

序列 IDPaTc_044561

步骤CPT/CPTL · CPT

证据PaCPT1在田间水分处理茎皮转录组中被报道。

边界Association only; transcript abundance is not direct proof of rubber yield.

来源10.1038/s41598-021-01026-7

银胶菊 · PaSRPP1

序列 IDPaTc_109994

步骤REF/SRPP 橡胶颗粒 · SRPP

证据表达关联不能直接作为橡胶产量因果证据。

边界转录本丰度不是橡胶产量的直接证明。

来源10.1038/s41598-021-01026-7

银胶菊 · PaSRPP1 promoter

序列 IDPV754023.1

步骤REF/SRPP 橡胶颗粒 · SRPP

证据Promoter sequence is regulatory reference evidence, not a complete gene-model crosswalk.

边界Promoter record is not a complete SRPP1 gene model.

来源10.1186/s13104-025-07448-0

通路导航与候选分布

MVA · MVA 甲羟戊酸途径

High 40 · Medium 3 · Low 4 MEP · MEP 非甲羟戊酸途径

High 23 · Medium 0 · Low 36 IPP/DMAPP/FPP · 异戊二烯供体

271

High 141 · Medium 83 · Low 47 CPT/CPTL · 顺式异戊二烯转移酶

High 0 · Medium 0 · Low 5 REF/SRPP · 橡胶颗粒相关蛋白

High 0 · Medium 0 · Low 7 Rubber · 橡胶生物合成

288

High 1 · Medium 287 · Low 0 Terpenoid · 萜类代谢

380

High 72 · Medium 107 · Low 201 Latex/root · 乳胶/根相关候选

4466

High 231 · Medium 1284 · Low 2951

377 MVA/MEP 与异戊二烯

点击筛选 · High 204 · Medium 86 · Low 87 4466 乳胶/根相关候选

点击筛选 · High 231 · Medium 1284 · Low 2951 300 橡胶生物合成

点击筛选 · High 1 · Medium 287 · Low 12 380 萜类代谢

点击筛选 · High 72 · Medium 107 · Low 201

候选基因表

当前筛选共 300 条候选，每页显示 10 条；当前为第 2/30 页。下载按钮导出当前筛选条件下最多 2000 条记录。点击上方通路卡或统计卡可快速筛选，证据摘要可通过基因详情和关联模块继续核查。

基因 ID	通路/步骤	等级	证据层	位置	关键证据	操作
`TkAUNG032090` TK1151: TkAUNG032090;TkA01G136280;TkA04G322970;TkA05G414370;TkA06G242080 OH-1004: LXL04_002662	橡胶生物合成橡胶生物合成	中等置信分数 6	GO表达定位PfamSwiss-ProtPPI共表达	CM104799.1:54230275-54231443 +	GO:0016740	基因详情表达蛋白组 JBrowse
`TkA01G419200` TK1151: TkA01G419200 OH-1004: LXL04_002811	橡胶生物合成橡胶生物合成	中等置信分数 6	GO表达定位PfamSwiss-ProtPPI共表达	CM104799.1:58762511-58766849 +	GO:0016740	基因详情表达蛋白组 JBrowse
`LXL04_003014` TK1151: - OH-1004: LXL04_003014	橡胶生物合成橡胶生物合成	中等置信分数 6	GO表达定位PfamSwiss-ProtPPI共表达	CM104799.1:64987114-64995744 +	GO:0016740	基因详情表达蛋白组 JBrowse
`TkA01G403630` TK1151: TkA01G403630;TkA01G404170 OH-1004: LXL04_003017	橡胶生物合成橡胶生物合成	中等置信分数 6	GO表达定位PfamSwiss-ProtPPI共表达	CM104799.1:65117260-65119850 +	GO:0016740	基因详情表达蛋白组 JBrowse
`TkA01G403130` TK1151: TkA01G403130 OH-1004: LXL04_003025	橡胶生物合成橡胶生物合成	中等置信分数 6	GO表达定位PfamSwiss-Prot共表达	CM104799.1:65255975-65257959 -	GO:0016114	基因详情表达蛋白组 JBrowse
`TkA01G402900` TK1151: TkA01G402900 OH-1004: LXL04_003027	橡胶生物合成橡胶生物合成	中等置信分数 6	GO表达定位PfamSwiss-Prot	CM104799.1:65333440-65335086 -	GO:0016114	基因详情表达蛋白组 JBrowse
`TkA01G125960` TK1151: TkA01G125960;TkA01G402270;TkA01G402300;TkA02G255500;TkA03G145420 OH-1004: LXL04_003037	橡胶生物合成橡胶生物合成	中等置信分数 6	GO表达定位PfamSwiss-Prot共表达	CM104799.1:65475441-65495510 -	GO:0016114	基因详情表达蛋白组 JBrowse
`TkA01G401900` TK1151: TkA01G401900 OH-1004: LXL04_003038	橡胶生物合成橡胶生物合成	中等置信分数 6	GO表达定位PfamSwiss-Prot	CM104799.1:65588485-65597235 +	GO:0016114	基因详情表达蛋白组 JBrowse
`LXL04_003040` TK1151: - OH-1004: LXL04_003040	橡胶生物合成橡胶生物合成	中等置信分数 6	GO表达定位Swiss-Prot	CM104799.1:65621689-65621968 -	GO:0016114	基因详情表达蛋白组 JBrowse
`TkA01G394920` TK1151: TkA01G394920 OH-1004: LXL04_003088	橡胶生物合成橡胶生物合成	中等置信分数 6	GO表达定位PfamSwiss-Prot共表达	CM104799.1:67189127-67192534 +	GO:0008299	基因详情表达蛋白组 JBrowse