TkA07G169510 | RubberDandelionOmics

基因概览

TkA07G169510

当前版本: TK1151 染色体: Chr07 坐标: 43504444-43508384 链方向: + 类型: protein_coding

cDNA / CDS / 蛋白序列

可用序列下载 CDS FASTA 蛋白 FASTA cDNA FASTA

cDNA

2658 bp · TkA07G169510|TK1151|cDNA

CTAGAAGTTCTTTGGTAAAATAAAAAAAAATTCAAAATATGGACTTGACTTAGCAATGAATGATGCTTTGGAGGAGACATGGAGGGCTTCTATTGGTGAAAAGAAAAGAGAAAATAATAATAAAGCAAATGACAAATAATGTGTGGAGATGCTTTCTTATGCTTTTCTGAGTTTTTTTTACACCTGCGGCCTGCCTATGCCCTTTGTCTACTCAATTTCTTGTTCTCCATTAATAAATAAATAAATAAAATTATTTCTCT...

CDS

下载 CDS FASTA

1404 bp · TkA07G169510|TK1151|CDS

ATGGAGGAGATGCTTCCGGCGGTGCCATTAAGCGTACGTAATCCAATCTGTAGCAAAACCCTCGTAATAATCACTGGGATACAACAACAACAGCAATTCATGGCGGATAAAATCAATTTCGACGATTGTAACAATCATTCACAAGATTTGAATTCGGATTCTGGGTTTCAAGAAAGCGAGGATGAATTGATGTCATTAGAAGGTGATCCTGATCGCATCTTTGAAACCTCATGTACGCTATCTGTAGTGAGCGATTCAAG...

蛋白

下载蛋白 FASTA

467 aa · TkA07G169510|TK1151|PROTEIN

MEEMLPAVPLSVRNPICSKTLVIITGIQQQQQFMADKINFDDCNNHSQDLNSDSGFQESEDELMSLEGDPDRIFETSCTLSVVSDSSSLCNEDFIAFESLNTLQEDGEKGVCLGDVATTGIVDDVATSEIVVSEKVSSVSRSVFEVDCVALWGFTSICGRRPEMEDAVATVPRFLKIPVQMLTGDKMTKSLSHLTAHFFGVYDGHGGSQVANYCSGRVHTALQEELEPLMAVGGGDESTTNNENSCQDLWKKAFIRCFLR...

上下游序列下载

序列方向与下载说明

上游/下游最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

多版本 ID 对照

输入 ID	`TkA07G169510`
TK1151 ID	TkA07G169510
OH-1004 ID	LXL04_028554
关系 / 置信度	跨参考版本对应关系 / 复杂对应关系
蛋白一致性 (%)	98.500
蛋白覆盖度 (%)	TK1151 100.000 / OH-1004 100.000 覆盖度与证据说明覆盖度为最高分比对片段的序列跨度占代表蛋白长度的比例。同源匹配不等同于功能验证。
版本	TK1151 / GWHBCHF00000000

查看完整 ID 对照表

SNP / Indel 变异与样本携带情况CRA009020 · TK1151

展开后加载该基因的变异记录。

基因基本信息与功能注释

基因 ID TkA07G169510

位置 Chr07:43504444-43508384 (+)

描述 Similar to HAB1: Protein phosphatase 2C 16

拟南芥 / 水稻参考基因与文献

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拟南芥

参考基因 ID	可能功能	对应论文 / DOI
`At1g72770`	脱落酸（ABA）信号通路的关键组成部分和抑制因子，调节多种ABA反应，如气孔关闭、种子萌发和营养生长抑制。	Gain-of-function and loss-of-function phenotypes of the protein phosphatase 2C HAB1 reveal its role as a negative regulator of abscisic acid signalling.2004 · DOI: 10.1046/j.1365-313x.2003.01966.x Enhancement of abscisic acid sensitivity and reduction of water consumption in Arabidopsis by combined inactivation of the protein phosphatases type 2C ABI1 and HAB1.2006 · DOI: 10.1104/pp.106.081018 A hypermorphic mutation in the protein phosphatase 2C HAB1 strongly affects ABA signaling in Arabidopsis.2006 · DOI: 10.1016/j.febslet.2006.07.047
`At1g17550`	脱落酸（ABA）信号通路的关键组成部分和抑制因子，调节多种ABA反应，如气孔关闭、种子萌发和营养生长抑制。	暂无已核实直接文献
`At5g57050`	脱落酸（ABA）信号通路抑制子，调控多种 ABA 响应，如气孔关闭、质膜渗透水流性（Pos）、高光胁迫、对葡萄糖的反应、种子萌发及营养生长抑制。	Arabidopsis abi1-1 and abi2-1 phosphatase mutations reduce abscisic acid-induced cytoplasmic calcium rises in guard cells.1999 · DOI: 10.1105/tpc.11.9.1785 The genes ABI1 and ABI2 are involved in abscisic acid- and drought-inducible expression of the Daucus carota L. Dc3 promoter in guard cells of transgenic Arabidopsis thaliana (L.) Heynh.2000 · DOI: 10.1007/s004250050692 Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar.2000 · PMID: 10950871 The ABI1 and ABI2 protein phosphatases 2C act in a negative feedback regulatory loop of the abscisic acid signalling pathway.2001 · DOI: 10.1046/j.1365-313x.2001.00965.x Abscisic acid activation of plasma membrane Ca(2+) channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in abi1-1 and abi2-1 protein phosphatase 2C mutants.2001 · DOI: 10.1105/tpc.010210 The role of ABA and the transpiration stream in the regulation of the osmotic water permeability of leaf cells.2001 · DOI: 10.1073/pnas.231471998 Hypersensitivity of abscisic acid-induced cytosolic calcium increases in the Arabidopsis farnesyltransferase mutant era1-2.2002 · DOI: 10.1105/tpc.010448 A calcium sensor and its interacting protein kinase are global regulators of abscisic acid signaling in Arabidopsis.2002 · DOI: 10.1016/s1534-5807(02)00229-0 Maternal Effects Govern Variable Dominance of Two Abscisic Acid Response Mutations in Arabidopsis thaliana.1994 · DOI: 10.1104/pp.105.4.1203 Hydrotropism in abscisic acid, wavy, and gravitropic mutants of Arabidopsis thaliana.2002 · DOI: 10.1007/s00425-002-0840-3 Control of Ascorbate Peroxidase 2 expression by hydrogen peroxide and leaf water status during excess light stress reveals a functional organisation of Arabidopsis leaves.2003 · DOI: 10.1046/j.1365-313x.2003.01656.x Synthesis of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is concertedly regulated by metabolic and stress-associated signals.2003 · DOI: 10.1104/pp.103.026294 Regulation of the ABA-sensitive Arabidopsis potassium channel gene GORK in response to water stress.2003 · DOI: 10.1016/s0014-5793(03)01118-9 The ABI2-dependent abscisic acid signalling controls HrpN-induced drought tolerance in Arabidopsis.2005 · DOI: 10.1007/s00425-004-1444-x Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance.2005 · DOI: 10.1104/pp.105.062257 Role of abscisic acid (ABA) and Arabidopsis thaliana ABA-insensitive loci in low water potential-induced ABA and proline accumulation.2006 · DOI: 10.1093/jxb/erj026 Fibrillin expression is regulated by abscisic acid response regulators and is involved in abscisic acid-mediated photoprotection.2006 · DOI: 10.1073/pnas.0501720103 Interaction between sugar and abscisic acid signalling during early seedling development in Arabidopsis.2008 · DOI: 10.1007/s11103-008-9308-6 A plasma membrane receptor kinase, GHR1, mediates abscisic acid- and hydrogen peroxide-regulated stomatal movement in Arabidopsis.2012 · DOI: 10.1105/tpc.112.100107 Abscisic acid induces the alcohol dehydrogenase gene in Arabidopsis.1996 · DOI: 10.1104/pp.111.2.381 Differential abscisic acid regulation of guard cell slow anion channels in Arabidopsis wild-type and abi1 and abi2 mutants.1997 · DOI: 10.1105/tpc.9.3.409 Abscisic acid-independent and abscisic acid-dependent regulation of proline biosynthesis following cold and osmotic stresses in Arabidopsis thaliana.1997 · DOI: 10.1007/s004380050397 The Arabidopsis ABSCISIC ACID-INSENSITIVE2 (ABI2) and ABI1 genes encode homologous protein phosphatases 2C involved in abscisic acid signal transduction.1997 · DOI: 10.1105/tpc.9.5.759 Convergence of the abscisic acid, CO2, and extracellular calcium signal transduction pathways in stomatal guard cells.1997 · DOI: 10.1104/pp.114.4.1557

水稻

参考基因 ID	可能功能	对应论文 / DOI
`Os01g0583100`	可能的蛋白磷酸酶，可能在脱落酸（ABA）信号中发挥作用。	暂无已核实直接文献
`Os05g0592800`	蛋白磷酸酶，作为脱落酸(ABA)信号的负调控因子。	ABA Regulates Subcellular Redistribution of OsABI-LIKE2, a Negative Regulator in ABA Signaling, to Control Root Architecture and Drought Resistance in Oryza sativa.2015 · DOI: 10.1093/pcp/pcv154

功能注释来源

查看注释来源

功能注释来源：OH1004 · LXL04_028554 · GCA_047496595.1_OSU_TarKok_2.0。此处为经 ID 对照查得的 OH1004 注释；下方拟南芥/水稻同源表使用当前查询参考的独立蛋白比对。

GO 注释（OH1004 来源）

GO:0006470 protein dephosphorylation 生物过程

GO:0009408 response to heat 生物过程

GO:0009409 response to cold 生物过程

GO:0009414 response to water deprivation 生物过程

GO:0009737 response to abscisic acid 生物过程

GO:0009738 abscisic acid-activated signaling pathway 生物过程

GO:0009787 regulation of abscisic acid-activated signaling pathway 生物过程

GO:0009788 negative regulation of abscisic acid-activated signaling pathway 生物过程

GO:0010119 regulation of stomatal movement 生物过程

GO:0048364 root development 生物过程

GO:1902531 regulation of intracellular signal transduction 生物过程

GO:0005634 nucleus 细胞组分

KEGG 基因交叉引用

ath:AT1G17550

ath:AT1G72770

ath:AT4G26080

dosa:Os01g0583100

dosa:Os05g0592800

osa:4339797

以下为同源蛋白关联的 KEGG 基因编号，不代表本基因已获得通路功能验证。

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基因表达

查看该基因在不同研究、组织与处理条件下的表达量。表达结果按研究与计量单位分别展示。

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数据来源与对应关系说明

表达数据来自公开转录组研究；参考版本、样本信息和表达单位见查询结果。跨参考版本的对应关系不唯一时，不自动选择表达记录；缺失值不视为表达量为零。

亚细胞定位 Top 5

以下为计算预测或同源注释，不能替代定位实验。

细胞核0.584

排名 1 · TkA07G169510 · TK1151

细胞质0.391

排名 2 · TkA07G169510 · TK1151

细胞膜0.117

排名 3 · TkA07G169510 · TK1151

内质网0.052

排名 4 · TkA07G169510 · TK1151

溶酶体／液泡0.042

排名 5 · TkA07G169510 · TK1151

LocPro · 直接预测 · 计算预测，非定位实验结果

进入亚细胞定位查询

预测功能结构域

结构域结果来自 Pfam-A/HMMER；位置为对应蛋白序列上的氨基酸坐标。

PF00481PP2C181-450 aa

PF13672PP2C_2201-398 aa

基因 ID	结构域编号	结构域名称	起始 aa	终止 aa	E 值	评分
TkA07G169510	`PF00481`	PP2C	181	450	6.5e-63	213.5
TkA07G169510	`PF13672`	PP2C_2	201	398	0.014	15.7

拟南芥 / 水稻蛋白同源

仅展示拟南芥和水稻；Swiss-Prot 为人工审校条目，TrEMBL 为补充序列候选。同源相似性不等同于实验验证。

下载当前结果

蛋白	物种	描述	一致性	数据库	置信等级
`Q9CAJ0`	拟南芥	sp\|Q9CAJ0\|P2C16_ARATH Protein phosphatase 2C 16	52.400%	Swiss-Prot	高置信
`Q9LNP9`	拟南芥	sp\|Q9LNP9\|P2C07_ARATH Protein phosphatase 2C 7	64.000%	Swiss-Prot	高置信
`O04719`	拟南芥	sp\|O04719\|P2C77_ARATH Protein phosphatase 2C 77	63.700%	Swiss-Prot	高置信
`Q0JLP9`	水稻	sp\|Q0JLP9\|P2C06_ORYSJ Probable protein phosphatase 2C 6	62.200%	Swiss-Prot	高置信
`Q6L4R7`	水稻	sp\|Q6L4R7\|P2C53_ORYSJ Protein phosphatase 2C 53	59.400%	Swiss-Prot	高置信

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