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Gene Card

Enter a TK1151 or OH-1004 gene ID to view sequences, annotations and analyses in the corresponding reference genome.
Flanking length, max 10000 bp

Gene overview

TkA05G445870
Reference: TK1151 Chr: Chr05 Coordinates: 111537577-111543034 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

2878 bp · TkA05G445870|TK1151|cDNA

GAGAAAACCAAACTCGGACGAAAATCAGAATCCCTCTTTTTTCTCTCTCTCCTCTCACCATCATCACCGGAGTTTTGACGTCCATGGCGATGCCAAGAAATCGACGAACAACTTCCCTACGTGACTCCGATAGTCGACTCGGTGAGTCCGACAAAATTGAAGGAACCGGTAGTTGGGACGCTATTGAGTGGACCAAGATCGATCAGCCTGTTTCGAGACCTGTACCTCATGGATTATCTGATTTTTTGTTCGAAGCTGAG...

2148 bp · TkA05G445870|TK1151|CDS

ATGCGGATTATTATTTTCGCTTTTCGTTCTCGAACCAAACAGAGACGAGCTGTGTTTGAGGCATTACTGAGGTGGGCAAGGCCACCAAGGCTATGGGATCTGTATACTTTTTCATCAGGCCCTTCAAGATTCAGCAATACAAGCCCTAGAATACGTTTAGTGAATGAATACCTACGACTCATTGGAATGAGATCACATGATCTATCACCAACCGCCATTGAAGATGGTTCTTTCACCTTCTCTAATGACTGGTGGAGAAT...

715 aa · TkA05G445870|TK1151|PROTEIN

MRIIIFAFRSRTKQRRAVFEALLRWARPPRLWDLYTFSSGPSRFSNTSPRIRLVNEYLRLIGMRSHDLSPTAIEDGSFTFSNDWWRITDINANYDMCPTYPFSLLLPKSIRDEDVLQACKFRARCRLPAISWCDARTGAVLARSSQPLVGLMMNMRSNADENLVGALCTQLSGGKKGRRKLYIADARPRKNALANGAMGGGSESSSNYFQSEIVFFGIDNIHAMRESLVRLRDYLDTYGTKSSDGMSSFLRNGGWTWGGG...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

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ID Mapping

Input IDTkA05G445870
TK1151 IDTkA05G445870
OH-1004 IDLXL04_022114
Relationship / confidenceRbh High Identity Coverage Synteny / Strict
Protein identity (%)99.600
Protein coverage (%)TK1151 100.000 / OH-1004 83.784
Coverage and evidence

Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.

Source versionTK1151 / GWHBCHF00000000
SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene IDTkA05G445870
LocationChr05:111537577-111543034 (-)
DescriptionSimilar to MTM1: Phosphatidylinositol-3-phosphatase myotubularin-1
Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene IDPossible functionPapers / DOI
At3g10550 Phosphatase with phosphoinositide 3'-phosphatase activity that can use phosphatidylinositol-3-phosphate (PtdIns3P) and phosphatidylinositol-3,5-diphosphate (PtdIns3,5P(2)) as substrates and produces phosphatidylinositol-5-phosphate (PtdIns5P).
At5g04540 Phosphatase with phosphoinositide 3'-phosphatase activity that can use phosphatidylinositol-3-phosphate (PtdIns3P) and phosphatidylinositol-3,5-diphosphate (PtdIns3,5P(2)) as substrates and produces phosphatidylinositol-5-phosphate (PtdIns5P).

Rice

No hit for this species in the current source table.

Functional annotation source
View annotation sources

Functional annotation source: OH1004 · LXL04_022114 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)
GO:0002091 negative regulation of receptor internalization Biological Process
GO:0006661 phosphatidylinositol biosynthetic process Biological Process
GO:0016311 dephosphorylation Biological Process
GO:0035556 intracellular signal transduction Biological Process
GO:0042631 cellular response to water deprivation Biological Process
GO:0045806 negative regulation of endocytosis Biological Process
GO:0046488 phosphatidylinositol metabolic process Biological Process
GO:0046856 phosphatidylinositol dephosphorylation Biological Process
GO:0060304 regulation of phosphatidylinositol dephosphorylation Biological Process
GO:0097062 dendritic spine maintenance Biological Process
GO:2000070 regulation of response to water deprivation Biological Process
GO:2000643 positive regulation of early endosome to late endosome transport Biological Process
KEGG gene cross-reference
ath:AT3G10550
ath:AT5G04540
bta:536810
hsa:8898
mmu:77116
These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Cytoplasm0.653
Rank 1 · TkA05G445870 · TK1151
Nucleus0.244
Rank 2 · TkA05G445870 · TK1151
Golgi apparatus0.155
Rank 3 · TkA05G445870 · TK1151
Cell membrane0.108
Rank 4 · TkA05G445870 · TK1151
Lysosome / Vacuole0.086
Rank 5 · TkA05G445870 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF06602Myotub-related79-455 aa
PF13350Y_phosphatase3297-325 aa
PF00102Y_phosphatase298-323 aa
PF125783-PAP488-544 aa
PF25539Bestrophin_2523-641 aa
PF15233SYCE1525-567 aa
PF30970DUF8768573-648 aa
Gene IDDomain IDDomain NameStart aaEnd aaE-valueScore
TkA05G445870PF06602Myotub-related794552.1e-122409.1
TkA05G445870PF13350Y_phosphatase32973250.06413.9
TkA05G445870PF00102Y_phosphatase2983230.1712.2
TkA05G445870PF125783-PAP4885440.0514.2
TkA05G445870PF25539Bestrophin_25236410.3511.1
TkA05G445870PF15233SYCE15255670.04914.4
TkA05G445870PF30970DUF87685736480.3811.6

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

ProteinOrganismDescriptionIdentityDatabaseConfidence
F4J3T8Arabidopsis thalianasp|F4J3T8|MYTM1_ARATH Phosphatidylinositol-3-phosphatase myotubularin-165.300%Swiss-ProtHigh
F4JWB3Arabidopsis thalianasp|F4JWB3|MYTM2_ARATH Phosphatidylinositol-3-phosphatase myotubularin-262.900%Swiss-ProtHigh

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