TkA05G055560 | RubberDandelionOmics

Gene overview

TkA05G055560

Reference: TK1151 Chr: Chr05 Coordinates: 14753004-14758237 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

3127 bp · TkA05G055560|TK1151|cDNA

GAAATTTAATGTAGAAATTAGTGATCTCAACTCTTTACAATAGAAATTTACATTTTTCAGCGTATAAAACAAACTCTGTTGAGTTTTCCCTCGCTGGTTCCCAACTACGTGAAGAAGAAGAAGAAGAAGAAGAAGAAGAATTCAAGAAATGGAGAAGAAGAAAGGCATGAAGAACATCTTCAAGAAGTTGCACATAGGCAGCAATCACGATCCTAATCGAACATCCAACGATTCAACGCCATCGTCATCGTCATCGTCGT...

CDS

Download CDS FASTA

2628 bp · TkA05G055560|TK1151|CDS

ATGGAGAAGAAGAAAGGCATGAAGAACATCTTCAAGAAGTTGCACATAGGCAGCAATCACGATCCTAATCGAACATCCAACGATTCAACGCCATCGTCATCGTCATCGTCGTCGTCTTGCTCCACTGCCGACCACCGTACATCTTCAACTCTCGCTGGACAAACCTCCGTCCAGTCTCCATCTACCGCCGCAAGTCCTCCTCCAACGTCTCCGACTGTCAATGTAACCTCGCGTCAACAAGATTACTATTCGTCAGAAGA...

Protein

Download Protein FASTA

875 aa · TkA05G055560|TK1151|PROTEIN

MEKKKGMKNIFKKLHIGSNHDPNRTSNDSTPSSSSSSSSCSTADHRTSSTLAGQTSVQSPSTAASPPPTSPTVNVTSRQQDYYSSEEEYQVQLALALSVSNSESRGDSDSDQIRAAKLLSLGQQSSNNHAPDRGDAAADKLSRQYWDYGLLDYDEKVVDGFYDVYGLSTEMSSQGKMPSLSDLETDPQSSGFEVIIVNRTIDPALEELFQVAHCIALDCPPAEVNLLVQRVAELVTEHMGGPVRDANIILGRWLERSTEL...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA05G055560`
TK1151 ID	TkA05G055560
OH-1004 ID	LXL04_025974
Relationship / confidence	Non Reciprocal Best Hit / Complex relationship
Protein identity (%)	47.000
Protein coverage (%)	TK1151 85.943 / OH-1004 84.099 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

Open Full ID Mapping

SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene ID TkA05G055560

Location Chr05:14753004-14758237 (-)

Description Similar to SIS8: Probable serine/threonine-protein kinase SIS8

Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At1g08720`	MAPKKK serine/threonine-protein kinase involved in the regulation of a MAP kinase cascade (probably including MPK3 and MPK6) that negatively regulates salicylic acid- (SA-) dependent defense responses, abscisic acid (ABA) signaling, and ethylene-induced senescence.	Negative regulation of defense responses in plants by a conserved MAPKK kinase.2001 · DOI: 10.1073/pnas.98.1.373 Overexpression of a kinase-deficient form of the EDR1 gene enhances powdery mildew resistance and ethylene-induced senescence in Arabidopsis.2002 · DOI: 10.1046/j.1365-313x.2002.01482.x Regulation of plant disease resistance, stress responses, cell death, and ethylene signaling in Arabidopsis by the EDR1 protein kinase.2005 · DOI: 10.1104/pp.105.060400 Costs and benefits of priming for defense in Arabidopsis.2006 · DOI: 10.1073/pnas.0510213103 Powdery mildew resistance conferred by loss of the ENHANCED DISEASE RESISTANCE1 protein kinase is suppressed by a missense mutation in KEEP ON GOING, a regulator of abscisic acid signaling.2008 · DOI: 10.1104/pp.108.127605 Mitogen-activated protein kinases 3 and 6 are required for full priming of stress responses in Arabidopsis thaliana.2009 · DOI: 10.1105/tpc.108.062158 The KEEP ON GOING protein of Arabidopsis recruits the ENHANCED DISEASE RESISTANCE1 protein to trans-Golgi network/early endosome vesicles.2011 · DOI: 10.1104/pp.110.171785 Arabidopsis ENHANCED DISEASE RESISTANCE 1 is required for pathogen-induced expression of plant defensins in nonhost resistance, and acts through interference of MYC2-mediated repressor function.2011 · DOI: 10.1111/j.1365-313x.2011.04651.x Negative regulation of defence signalling pathways by the EDR1 protein kinase.2011 · DOI: 10.1111/j.1364-3703.2011.00708.x An Arabidopsis mutant with enhanced resistance to powdery mildew.1998 · DOI: 10.1105/tpc.10.6.947
`At1g73660`	Acts as a negative regulator of salt tolerance.	The genetic locus At1g73660 encodes a putative MAPKKK and negatively regulates salt tolerance in Arabidopsis.2008 · DOI: 10.1007/s11103-008-9306-8 SIS8, a putative mitogen-activated protein kinase kinase kinase, regulates sugar-resistant seedling development in Arabidopsis.2014 · DOI: 10.1111/tpj.12404
`At5g03730`	Acts as a negative regulator in the ethylene response pathway.	CTR1 phosphorylates the central regulator EIN2 to control ethylene hormone signaling from the ER membrane to the nucleus in Arabidopsis.2012 · DOI: 10.1073/pnas.1214848109 Unsaturation of very-long-chain ceramides protects plant from hypoxia-induced damages by modulating ethylene signaling in Arabidopsis.2015 · DOI: 10.1371/journal.pgen.1005143 CTR1, a negative regulator of the ethylene response pathway in Arabidopsis, encodes a member of the raf family of protein kinases.1993 · DOI: 10.1016/0092-8674(93)90119-b

Rice

No hit for this species in the current source table.

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_025974 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0000165 MAPK cascade Biological Process

GO:0001666 response to hypoxia Biological Process

GO:0002229 defense response to oomycetes Biological Process

GO:0007165 signal transduction Biological Process

GO:0009414 response to water deprivation Biological Process

GO:0009617 response to bacterium Biological Process

GO:0009620 response to fungus Biological Process

GO:0009651 response to salt stress Biological Process

GO:0009686 gibberellin biosynthetic process Biological Process

GO:0009723 response to ethylene Biological Process

GO:0009738 abscisic acid-activated signaling pathway Biological Process

GO:0009744 response to sucrose Biological Process

KEGG gene cross-reference

ath:AT1G08720

ath:AT1G73660

ath:AT5G03730

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

Open Annotation Module

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Cell membrane0.440

Rank 1 · TkA05G055560 · TK1151

Cytoplasm0.393

Rank 2 · TkA05G055560 · TK1151

Nucleus0.231

Rank 3 · TkA05G055560 · TK1151

Golgi apparatus0.088

Rank 4 · TkA05G055560 · TK1151

Endoplasmic reticulum0.061

Rank 5 · TkA05G055560 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF12330Haspin_kinase35-80 aa

PF14381EDR1_CTR1_ARMC3_pept138-336 aa

PF12330Haspin_kinase602-633 aa

PF07714PK_Tyr_Ser-Thr605-854 aa

PF00069Pkinase606-852 aa

PF01636APH615-658 aa

PF01636APH721-750 aa

PF14531Kinase-like722-833 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA05G055560	`PF12330`	Haspin_kinase	35	80	0.0064	16.3
TkA05G055560	`PF14381`	EDR1_CTR1_ARMC3_pept	138	336	6.1e-74	248.9
TkA05G055560	`PF12330`	Haspin_kinase	602	633	0.0064	16.3
TkA05G055560	`PF07714`	PK_Tyr_Ser-Thr	605	854	2.9e-62	211.0
TkA05G055560	`PF00069`	Pkinase	606	852	3.6e-50	171.5
TkA05G055560	`PF01636`	APH	615	658	0.016	15.7
TkA05G055560	`PF01636`	APH	721	750	0.016	15.7
TkA05G055560	`PF14531`	Kinase-like	722	833	0.046	13.7
TkA05G055560	`PF12330`	Haspin_kinase	725	754	0.0064	16.3

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

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Protein	Organism	Description	Identity	Database	Confidence
`Q9FPR3`	Arabidopsis thaliana	sp\|Q9FPR3\|EDR1_ARATH Serine/threonine-protein kinase EDR1	52.100%	Swiss-Prot	High
`Q9C9U5`	Arabidopsis thaliana	sp\|Q9C9U5\|SIS8_ARATH Probable serine/threonine-protein kinase SIS8	40.700%	Swiss-Prot	Medium
`Q05609`	Arabidopsis thaliana	sp\|Q05609\|CTR1_ARATH Serine/threonine-protein kinase CTR1	37.400%	Swiss-Prot	Medium

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