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Gene Card

Enter a TK1151 or OH-1004 gene ID to view sequences, annotations and analyses in the corresponding reference genome.
Flanking length, max 10000 bp
Examples TkA01G624900 LXL04_000258

Gene overview

TkA04G501260
Reference: TK1151 Chr: Chr04 Coordinates: 126549663-126556549 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

Download cDNA FASTA

4167 bp · TkA04G501260|TK1151|cDNA

GAGTATTATTTGCAAGAGCGATTTAATTGGGAAAGGTTACTCCGATCGACATAACCTACTGTGGCGTGCCTACCTCTCCCCCTCTGCCGCTGCCTGCTCCGGACTGGCTGACTGACTCAGTAACTCAGCAACTCCGGCATCCGCCGCCGCATACTACTTCTTCCTACATCCGACTGCTGAGTGTTCCTTTTCGTCTATTTGAAATATTCGAGTATCTACTATTCTATAAGTGCTGTGATCTAAGATCTTGATCGACTTGT...

CDS

Download CDS FASTA

3690 bp · TkA04G501260|TK1151|CDS

ATGGCAAATTCATCTATACCTGGTATCCTGGAGAAGGTAAGAAGCTATGCATTTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTGTTTTGCGTTATATAAAATGTCATATATTGCACAAATTGTTGATGTTTGGTTTATGCAGATGACTGGGAAGGATAAAGATTACAGATACATGGCAACTTCGGACCTATTAAACGAATTAAACAAAGAGGGGTTTAAACT...

Protein

Download Protein FASTA

1229 aa · TkA04G501260|TK1151|PROTEIN

MANSSIPGILEKVRSYAFSSSSSSSSSSSSSSSSSSSSSSCFALYKMSYIAQIVDVWFMQMTGKDKDYRYMATSDLLNELNKEGFKLDTDLELRLSNIVLQQLDDAAGDVSGLAVKCLAPLVKKIQEAQVLEMTHKLCDKLLNGKDQHRDIASIALKTIFSEVPTSSVAQSVLVSVSPKLIGGITNPAMKTDIKCECLDILCDILHKFGNLMTSDHEMLLGALLPQLSSNQASVRKKTVSCIASLASSLSDDLLAKATVE...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

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ID Mapping

Input IDTkA04G501260
TK1151 IDTkA04G501260
OH-1004 IDLXL04_039071
Relationship / confidenceRbh High Identity Coverage Synteny / Strict
Protein identity (%)98.800
Protein coverage (%)TK1151 99.919 / OH-1004 97.456
Coverage and evidence

Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.

Source versionTK1151 / GWHBCHF00000000
Open Full ID Mapping
SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene IDTkA04G501260
LocationChr04:126549663-126556549 (-)
DescriptionSimilar to CAND1: Cullin-associated NEDD8-dissociated protein 1
Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene IDPossible functionPapers / DOI
At2g02560 Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes.
AtCAND1, a HEAT-repeat protein that participates in auxin signaling in Arabidopsis.2004 · DOI: 10.1104/pp.104.044495
Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation.2004 · DOI: 10.1105/tpc.021949
Arabidopsis ETA2, an apparent ortholog of the human cullin-interacting protein CAND1, is required for auxin responses mediated by the SCF(TIR1) ubiquitin ligase.2004 · DOI: 10.1105/tpc.021923
The HVE/CAND1 gene is required for the early patterning of leaf venation in Arabidopsis.2006 · DOI: 10.1242/dev.02554
Genetic analysis of CAND1-CUL1 interactions in Arabidopsis supports a role for CAND1-mediated cycling of the SCFTIR1 complex.2008 · DOI: 10.1073/pnas.0804144105

Rice

No hit for this species in the current source table.

Functional annotation source
View annotation sources

Functional annotation source: OH1004 · LXL04_039071 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)
GO:0006351 DNA-templated transcription Biological Process
GO:0009733 response to auxin Biological Process
GO:0010051 xylem and phloem pattern formation Biological Process
GO:0010228 vegetative to reproductive phase transition of meristem Biological Process
GO:0010265 SCF complex assembly Biological Process
GO:0016567 protein ubiquitination Biological Process
GO:0030154 cell differentiation Biological Process
GO:0043086 negative regulation of catalytic activity Biological Process
GO:0045893 positive regulation of DNA-templated transcription Biological Process
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly Biological Process
GO:0000151 ubiquitin ligase complex Cellular Component
GO:0005576 extracellular region Cellular Component
KEGG gene cross-reference
ath:AT2G02560
hsa:55832
mmu:71902
pon:100173509
rno:117152
These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.
Open Annotation Module

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene
Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Cytoplasm0.529
Rank 1 · TkA04G501260 · TK1151
Nucleus0.444
Rank 2 · TkA04G501260 · TK1151
Golgi apparatus0.113
Rank 3 · TkA04G501260 · TK1151
Lysosome / Vacuole0.077
Rank 4 · TkA04G501260 · TK1151
Endoplasmic reticulum0.067
Rank 5 · TkA04G501260 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF27961CSNKA2IP19-41 aa
PF12755Vac14_Fab1_bd47-78 aa
PF23271HEAT_GCN150-147 aa
PF08389Xpo173-130 aa
PF25767ARM_TBCD_2nd75-138 aa
PF25786HEAT_GCN1_C92-130 aa
PF24492HEAT_ECM2994-139 aa
PF25782TPR_CAND195-126 aa
Gene IDDomain IDDomain NameStart aaEnd aaE-valueScore
TkA04G501260PF27961CSNKA2IP19412.68.2
TkA04G501260PF12755Vac14_Fab1_bd47780.003718.6
TkA04G501260PF23271HEAT_GCN1501473.5e-1350.8
TkA04G501260PF08389Xpo1731300.1412.9
TkA04G501260PF25767ARM_TBCD_2nd751380.1811.9
TkA04G501260PF25786HEAT_GCN1_C921300.3111.8
TkA04G501260PF24492HEAT_ECM29941395.3e-1040.4
TkA04G501260PF25782TPR_CAND1951267.9e-50169.2
TkA04G501260PF24993GNC1_N951451.3e-0732.2
TkA04G501260PF25780TPR_IPO5961438.6e-0730.1
TkA04G501260PF25151TPR_Trm732_C961300.01715.7
TkA04G501260PF08623TIP120971405.8e-55186.4
TkA04G501260PF02985HEAT971248.9e-1657.2
TkA04G501260PF12755Vac14_Fab1_bd971410.003718.6
TkA04G501260PF13646HEAT_2991383.3e-1660.1
TkA04G501260PF23227HEAT_MROH2B_C991578.5e-1039.1

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

ProteinOrganismDescriptionIdentityDatabaseConfidence
Q8L5Y6Arabidopsis thalianasp|Q8L5Y6|CAND1_ARATH Cullin-associated NEDD8-dissociated protein 178.800%Swiss-ProtHigh

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