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Gene Card

Enter a TK1151 or OH-1004 gene ID to view sequences, annotations and analyses in the corresponding reference genome.
Flanking length, max 10000 bp
Examples TkA01G624900 LXL04_000258

Gene overview

TkA04G102250
Reference: TK1151 Chr: Chr04 Coordinates: 26578917-26582833 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

Download cDNA FASTA

2187 bp · TkA04G102250|TK1151|cDNA

TTTGGAGTTATACGTTTCGTTGGAAGTTATATTCCATAGTTTTTCAGATCGGGGACTACAAATAACCACATCTCGGCACGTCTGTCATTTAGACCGCCGTGCGATTCTCCGGCGGCCAAATCCCGGCGAATCTCCGAGTTAAAGGCGCAAATCCATACTAAGAAATGGCTGTTCCGCAAGAGAGATGGTGTGTTGTCACTGGAGGAAGAGGCTTTGCTGCACGGCATTTAGTTGATATGCTTATTCGGTATGAAATATAT...

CDS

Download CDS FASTA

1695 bp · TkA04G102250|TK1151|CDS

ATGGCTGTTCCGCAAGAGAGATGGTGTGTTGTCACTGGAGGAAGAGGCTTTGCTGCACGGCATTTAGTTGATATGCTTATTCGGTATGAAATATATTCAGTTCGGATTGCTGATTTGGGACCTGATATAAAGCTGGACACACATGAAGAGAAGGGAAATCTTGGTCAAGCTTTACGGTTAGGTCGTGCTCAATATGTATCTATGGATCTCCGCGACAAATCTCAAGTATATAAAGCTTGTGAAGGGGCCGAAGTTGTTTT...

Protein

Download Protein FASTA

564 aa · TkA04G102250|TK1151|PROTEIN

MAVPQERWCVVTGGRGFAARHLVDMLIRYEIYSVRIADLGPDIKLDTHEEKGNLGQALRLGRAQYVSMDLRDKSQVYKACEGAEVVFHMAAPDSSINNYQLHHSVNVQGTKNIIDACTKLNVKRLIYTSSPSVVFDGIHGIHNGEETLPYASKHNDSYSETKAEGEALVIKANGVNGLLTCCIRPSSIFGPGDKLLVPSLVAAARAGKSKFIIGDGTNMYDFTYVENVAHAHVCAERALASDGSASKKAAGEAYFITNME...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

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ID Mapping

Input IDTkA04G102250
TK1151 IDTkA04G102250
OH-1004 IDLXL04_035859
Relationship / confidenceRbh High Identity Coverage Synteny / Strict
Protein identity (%)100.000
Protein coverage (%)TK1151 100.000 / OH-1004 100.000
Coverage and evidence

Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.

Source versionTK1151 / GWHBCHF00000000
Open Full ID Mapping
SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene IDTkA04G102250
LocationChr04:26578917-26582833 (-)
DescriptionSimilar to 3BETAHSD/D2: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2
Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene IDPossible functionPapers / DOI
At2g26260 3beta-hydroxysteroid-dehydrogenase/decarboxylase involved in sterol synthesis.
Molecular and enzymatic characterizations of novel bifunctional 3beta-hydroxysteroid dehydrogenases/C-4 decarboxylases from Arabidopsis thaliana.2006 · DOI: 10.1074/jbc.m604431200
Overexpression of 3β-hydroxysteroid dehydrogenases/C-4 decarboxylases causes growth defects possibly due to abnormal auxin transport in Arabidopsis.2012 · DOI: 10.1007/s10059-012-0102-6
At1g47290 3beta-hydroxysteroid-dehydrogenase/decarboxylase involved in sterol synthesis.
Molecular and enzymatic characterizations of novel bifunctional 3beta-hydroxysteroid dehydrogenases/C-4 decarboxylases from Arabidopsis thaliana.2006 · DOI: 10.1074/jbc.m604431200
Overexpression of 3β-hydroxysteroid dehydrogenases/C-4 decarboxylases causes growth defects possibly due to abnormal auxin transport in Arabidopsis.2012 · DOI: 10.1007/s10059-012-0102-6
At2g43420 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3. No verified direct reference in this release

Rice

No hit for this species in the current source table.

Functional annotation source
View annotation sources

Functional annotation source: OH1004 · LXL04_035859 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)
GO:0006695 cholesterol biosynthetic process Biological Process
GO:0007224 smoothened signaling pathway Biological Process
GO:0008203 cholesterol metabolic process Biological Process
GO:0016126 sterol biosynthetic process Biological Process
GO:0033489 cholesterol biosynthetic process via desmosterol Biological Process
GO:0033490 cholesterol biosynthetic process via lathosterol Biological Process
GO:0036197 zymosterol biosynthetic process Biological Process
GO:0060918 auxin transport Biological Process
GO:0099402 plant organ development Biological Process
GO:0005783 endoplasmic reticulum Cellular Component
GO:0005789 endoplasmic reticulum membrane Cellular Component
GO:0005811 lipid droplet Cellular Component
KEGG gene cross-reference
ath:AT1G47290
ath:AT2G26260
ath:AT2G43420
hsa:50814
mmu:18194
These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.
Open Annotation Module

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene
Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Endoplasmic reticulum0.566
Rank 1 · TkA04G102250 · TK1151
Cytoplasm0.148
Rank 2 · TkA04G102250 · TK1151
Golgi apparatus0.128
Rank 3 · TkA04G102250 · TK1151
Cell membrane0.117
Rank 4 · TkA04G102250 · TK1151
Nucleus0.098
Rank 5 · TkA04G102250 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF010733Beta_HSD10-284 aa
PF01370Epimerase10-238 aa
PF02719Polysacc_synt_210-130 aa
PF05368NmrA10-130 aa
PF16363GDP_Man_Dehyd11-234 aa
PF07993NAD_binding_411-210 aa
PF13460NAD_binding_1013-32 aa
PF13460NAD_binding_1061-158 aa
Gene IDDomain IDDomain NameStart aaEnd aaE-valueScore
TkA04G102250PF010733Beta_HSD102841.8e-77260.8
TkA04G102250PF01370Epimerase102387.5e-35121.2
TkA04G102250PF02719Polysacc_synt_2101304.8e-0936.5
TkA04G102250PF05368NmrA101303.1e-0524.4
TkA04G102250PF16363GDP_Man_Dehyd112349e-1762.2
TkA04G102250PF07993NAD_binding_4112101.1e-1455.0
TkA04G102250PF13460NAD_binding_1013323.6e-0937.5
TkA04G102250PF13460NAD_binding_10611583.6e-0937.5
TkA04G102250PF04321RmlD_sub_bind632831.3e-1041.6
TkA04G102250PF02719Polysacc_synt_22452784.8e-0936.5
TkA04G102250PF25127DUF78192803350.0006720.3
TkA04G102250PF16363GDP_Man_Dehyd3283519e-1762.2
TkA04G102250PF10166DUF23683313450.1512.4
TkA04G102250PF02453Reticulon3815381.1e-30107.4
TkA04G102250PF10166DUF23684885320.1512.4

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

ProteinOrganismDescriptionIdentityDatabaseConfidence
Q67ZE1Arabidopsis thalianasp|Q67ZE1|HSDD2_ARATH 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 267.000%Swiss-ProtHigh
Q9FX01Arabidopsis thalianasp|Q9FX01|HSDD1_ARATH 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 167.000%Swiss-ProtHigh
A9X4U2Arabidopsis thalianasp|A9X4U2|HSDD3_ARATH 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 340.700%Swiss-ProtMedium

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