TkA03G445400 | RubberDandelionOmics

Gene overview

TkA03G445400

Reference: TK1151 Chr: Chr03 Coordinates: 111073928-111078443 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

2736 bp · TkA03G445400|TK1151|cDNA

CTCTTTGCTCAGATAAACTTTATATATGTCTGCCGGTTCCACATCGCACTCCGTTCGCTCACACGGGGTTAAAAACATCGGTCATCAAAGCACACTTTTGCAGAACCCCTTCTACCCTCCCCCTCCCCCCACCGCTGTAGTAGTCTACCGCCGTTCGCTTGCCGGTCGAGAAATCTCCAAGCAACTGAAAATCCAACACTTCTTCTATCTGCTCAGATCCTTAACTTTTAATTGCATGCTCCCAGATAAAGAAATTCTAA...

CDS

Download CDS FASTA

1401 bp · TkA03G445400|TK1151|CDS

ATGAGGCTTGGAGCAGATGTCATAGTTTTCACCCGCTATTTGACCGACAGGACATTGACTCAAAGCATCGGTCTTCTATCATATACATTTTTAACACAATCAGGATATGACAGGATAGTTGTTCCCATGGTTCACTATGAGTTCAACTTTCTGACAGGCTGTTTTGACCCCTTACAAACCTCAAATGAAAACCTTTCTGTCATCTTAAAATGGTCTCCATTTTCAACAAAGGAAGAGCTACTGAAACAATTCGAAGATGT...

Protein

Download Protein FASTA

466 aa · TkA03G445400|TK1151|PROTEIN

MRLGADVIVFTRYLTDRTLTQSIGLLSYTFLTQSGYDRIVVPMVHYEFNFLTGCFDPLQTSNENLSVILKWSPFSTKEELLKQFEDVGSHGTKVIIYNLWLDEDGNMELDFESDPEDICIAWDGKGKGKEGSRMAVSEQHIANRLKYSLRAYLSVLYLKLPDTFAMVLRGKVILYHNIASDLKHTEFIMYKPHNDGCVEGTVITTIGFLKEAPNINVHGFNVYHKNRLILPFWPVVMFADSRGRGVVGVLEANFIEPTHN...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA03G445400`
TK1151 ID	TkA03G445400
OH-1004 ID	LXL04_009532
Relationship / confidence	Rbh Below Probable Coverage Or Synteny Threshold / Review
Protein identity (%)	100.000
Protein coverage (%)	TK1151 100.000 / OH-1004 68.429 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

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SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene ID TkA03G445400

Location Chr03:111073928-111078443 (-)

Description Similar to MORC6: Protein MICRORCHIDIA 6

Arabidopsis / Rice Reference Genes and Papers

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Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At1g19100`	Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing.	MORC family ATPases required for heterochromatin condensation and gene silencing.2012 · DOI: 10.1126/science.1221472 Involvement of a GHKL ATPase in RNA-directed DNA methylation in Arabidopsis thaliana.2012 · DOI: 10.1016/j.cub.2012.03.061 The stochastic silencing phenotype of Arabidopsis morc6 mutants reveals a role in efficient RNA-directed DNA methylation.2013 · DOI: 10.1111/tpj.12246 Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes.2016 · DOI: 10.1371/journal.pgen.1005998 Two Components of the RNA-Directed DNA Methylation Pathway Associate with MORC6 and Silence Loci Targeted by MORC6 in Arabidopsis.2016 · DOI: 10.1371/journal.pgen.1006026
`At4g36280`	Mediator of defense signaling triggered by distinct classes of R proteins.	Endosome-associated CRT1 functions early in resistance gene-mediated defense signaling in Arabidopsis and tobacco.2010 · DOI: 10.1105/tpc.109.071662 CRT1 is a nuclear-translocated MORC endonuclease that participates in multiple levels of plant immunity.2012 · DOI: 10.1038/ncomms2279 Transcriptional gene silencing by Arabidopsis microrchidia homologues involves the formation of heteromers.2014 · DOI: 10.1073/pnas.1406611111
`At4g36290`	Mediator of defense signaling triggered by distinct classes of R proteins.	MORC family ATPases required for heterochromatin condensation and gene silencing.2012 · DOI: 10.1126/science.1221472 Transcriptional gene silencing by Arabidopsis microrchidia homologues involves the formation of heteromers.2014 · DOI: 10.1073/pnas.1406611111
`At4g36270`	Exhibits ATPase activity.	No verified direct reference in this release
`At5g50780`	Exhibits ATPase activity.	Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes.2016 · DOI: 10.1371/journal.pgen.1005998

Rice

No hit for this species in the current source table.

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_009532 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0002230 positive regulation of defense response to virus by host Biological Process

GO:0006281 DNA repair Biological Process

GO:0006282 regulation of DNA repair Biological Process

GO:0006325 chromatin organization Biological Process

GO:0009626 plant-type hypersensitive response Biological Process

GO:0031047 regulatory ncRNA-mediated gene silencing Biological Process

GO:0034052 positive regulation of plant-type hypersensitive response Biological Process

GO:0051607 defense response to virus Biological Process

GO:0060966 regulation of gene silencing by regulatory ncRNA Biological Process

GO:0080188 gene silencing by siRNA-directed DNA methylation Biological Process

GO:0098542 defense response to other organism Biological Process

GO:1900426 positive regulation of defense response to bacterium Biological Process

KEGG gene cross-reference

ath:AT1G19100

ath:AT4G24970

ath:AT4G36280

ath:AT4G36290

ath:AT5G50780

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

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Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Nucleus0.929

Rank 1 · TkA03G445400 · TK1151

Cytoplasm0.138

Rank 2 · TkA03G445400 · TK1151

Cell membrane0.021

Rank 3 · TkA03G445400 · TK1151

Mitochondrion0.018

Rank 4 · TkA03G445400 · TK1151

Endoplasmic reticulum0.011

Rank 5 · TkA03G445400 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF17942Morc6_S5147-285 aa

PF16526CLZ270-281 aa

PF16454PI3K_P85_iSH2375-463 aa

PF26095CC_Bre1410-461 aa

PF16526CLZ420-460 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA03G445400	`PF17942`	Morc6_S5	147	285	3.6e-60	202.8
TkA03G445400	`PF16526`	CLZ	270	281	0.087	13.9
TkA03G445400	`PF16454`	PI3K_P85_iSH2	375	463	0.078	13.3
TkA03G445400	`PF26095`	CC_Bre1	410	461	0.3	12.1
TkA03G445400	`PF16526`	CLZ	420	460	0.087	13.9

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

Protein	Organism	Description	Identity	Database	Confidence
`Q56Y74`	Arabidopsis thaliana	sp\|Q56Y74\|MORC6_ARATH Protein MICRORCHIDIA 6	60.800%	Swiss-Prot	Medium
`Q5FV35`	Arabidopsis thaliana	sp\|Q5FV35\|MORC2_ARATH Protein MICRORCHIDIA 2	45.300%	Swiss-Prot	Medium
`Q84WV6`	Arabidopsis thaliana	sp\|Q84WV6\|MORC1_ARATH Protein MICRORCHIDIA 1	43.600%	Swiss-Prot	Medium
`F4JPP0`	Arabidopsis thaliana	sp\|F4JPP0\|MORC3_ARATH Protein MICRORCHIDIA 3	48.900%	Swiss-Prot	Medium
`F4KAF2`	Arabidopsis thaliana	sp\|F4KAF2\|MORC4_ARATH Protein MICRORCHIDIA 4	42.300%	Swiss-Prot	Medium

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