TkA01G030790 | RubberDandelionOmics

Gene overview

TkA01G030790

Reference: TK1151 Chr: Chr01 Coordinates: 7912617-7919350 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

2615 bp · TkA01G030790|TK1151|cDNA

TCTCCAGCTCGTGGATGTGTGGGTAACTCCAATGCGGGCCCCACTCAGACGCTCATCTTCCACTATCAATTAAATCATCACTGAAACAAAACCGACACAAATTCACACACACACACACACACACACACACACACACACACACACAACTCACCCGTGTGGATCCCTCCCTCCGACGCCGTCTTGCCATGAAAAGGGGGATACCCACCTCCTCCTCCTCCTCCCACCTCCGCCGTCTCTACTTCCTATCTCTAATGTCATTA...

CDS

Download CDS FASTA

1068 bp · TkA01G030790|TK1151|CDS

ATGAAAAGGGGGATACCCACCTCCTCCTCCTCCTCCCACCTCCGCCGTCTCTACTTCCTATCTCTAATGTCATTAATCCTATCCTTCTCCCTTTCTCCTCTCGCCCCTGTCCTCGCCGACACAGATCAGGAGGAGCTGCTTGAAGATACCGGCGTTGTCTTAGATAATAACGCCACTGTTACTTCTATTAATGCTTCTTCTACTACGGATAGAGAGAACAGCTTTGCTGGCATGATCGATCGTGCTTTGGAGAAAGAGTT...

Protein

Download Protein FASTA

355 aa · TkA01G030790|TK1151|PROTEIN

MKRGIPTSSSSSHLRRLYFLSLMSLILSFSLSPLAPVLADTDQEELLEDTGVVLDNNATVTSINASSTTDRENSFAGMIDRALEKEFTESDQNQEEDAGSFNSSVAGQQAVLETVARVKSKKNDTKDDKSFQLHHVFDTDHGAEETPTLIDRKDNVFIISNFKSKYPVLQLDLRLISDLVVVIVSATCGGIAFACAGQPVITGYLLAGSVVGPGGLDVVSELVQVETVAQFGVIFLLFALGLEFSMAKLKVVRVVAVLGG...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA01G030790`
TK1151 ID	TkA01G030790
OH-1004 ID	LXL04_005644
Relationship / confidence	Sequence Supported Annotation Or Model Conflict / Review
Protein identity (%)	99.700
Protein coverage (%)	TK1151 100.000 / OH-1004 59.167 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

Open Full ID Mapping

SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene ID TkA01G030790

Location Chr01:7912617-7919350 (-)

Description Similar to KEA4: K(+) efflux antiporter 4

Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At5g11800`	May act as an electroneutral K⁺/H⁺ antiporter in K⁺ homeostasis and osmotic adjustment.	Golgi-localized cation/proton exchangers regulate ionic homeostasis and skotomorphogenesis in Arabidopsis.2019 · DOI: 10.1111/pce.13452 K + Efflux Antiporters 4, 5, and 6 Mediate pH and K + Homeostasis in Endomembrane Compartments.2018 · DOI: 10.1104/pp.18.01053 Evidence for potassium transport activity of Arabidopsis KEA1-KEA6.2019 · DOI: 10.1038/s41598-019-46463-7
`At2g19600`	May act as an electroneutral K⁺/H⁺ antiporter in K⁺ homeostasis and osmotic adjustment.	A novel AtKEA gene family, homolog of bacterial K+/H+ antiporters, plays potential roles in K+ homeostasis and osmotic adjustment in Arabidopsis.2013 · DOI: 10.1371/journal.pone.0081463 Golgi-localized cation/proton exchangers regulate ionic homeostasis and skotomorphogenesis in Arabidopsis.2019 · DOI: 10.1111/pce.13452 K + Efflux Antiporters 4, 5, and 6 Mediate pH and K + Homeostasis in Endomembrane Compartments.2018 · DOI: 10.1104/pp.18.01053 Evidence for potassium transport activity of Arabidopsis KEA1-KEA6.2019 · DOI: 10.1038/s41598-019-46463-7
`At5g51710`	May act as an electroneutral K⁺/H⁺ antiporter in K⁺ homeostasis and osmotic adjustment.	A novel AtKEA gene family, homolog of bacterial K+/H+ antiporters, plays potential roles in K+ homeostasis and osmotic adjustment in Arabidopsis.2013 · DOI: 10.1371/journal.pone.0081463 Golgi-localized cation/proton exchangers regulate ionic homeostasis and skotomorphogenesis in Arabidopsis.2019 · DOI: 10.1111/pce.13452 K + Efflux Antiporters 4, 5, and 6 Mediate pH and K + Homeostasis in Endomembrane Compartments.2018 · DOI: 10.1104/pp.18.01053 Evidence for potassium transport activity of Arabidopsis KEA1-KEA6.2019 · DOI: 10.1038/s41598-019-46463-7
`At4g00630`	May act as an electroneutral K⁺/H⁺ antiporter regulating monovalent-cation and pH homeostasis in plastids.	Arabidopsis KEA2, a homolog of bacterial KefC, encodes a K(+)/H(+) antiporter with a chloroplast transit peptide.2012 · DOI: 10.1016/j.bbamem.2012.04.011 A novel AtKEA gene family, homolog of bacterial K+/H+ antiporters, plays potential roles in K+ homeostasis and osmotic adjustment in Arabidopsis.2013 · DOI: 10.1371/journal.pone.0081463 Envelope K+/H+ Antiporters AtKEA1 and AtKEA2 Function in Plastid Development.2016 · DOI: 10.1104/pp.16.00995 Plastidial transporters KEA1 and KEA2 at the inner envelope membrane adjust stromal pH in the dark.2021 · DOI: 10.1111/nph.17042 Loss of function of the chloroplast membrane K + /H + antiporters AtKEA1 and AtKEA2 alters the ROS and NO metabolism but promotes drought stress resilience.2021 · DOI: 10.1016/j.plaphy.2021.01.010 Loss of inner-envelope K+/H+ exchangers impairs plastid rRNA maturation and gene expression.2021 · DOI: 10.1093/plcell/koab123 Exogenous sucrose influences KEA1 and KEA2 to regulate abscisic acid-mediated primary root growth in Arabidopsis.2022 · DOI: 10.1016/j.plantsci.2022.111209
`At1g01790`	May act as an electroneutral K⁺/H⁺ antiporter in chloroplast K⁺ homeostasis, osmotic adjustment and plastid development.	A novel AtKEA gene family, homolog of bacterial K+/H+ antiporters, plays potential roles in K+ homeostasis and osmotic adjustment in Arabidopsis.2013 · DOI: 10.1371/journal.pone.0081463 Envelope K+/H+ Antiporters AtKEA1 and AtKEA2 Function in Plastid Development.2016 · DOI: 10.1104/pp.16.00995 Evidence for potassium transport activity of Arabidopsis KEA1-KEA6.2019 · DOI: 10.1038/s41598-019-46463-7 Plastidial transporters KEA1 and KEA2 at the inner envelope membrane adjust stromal pH in the dark.2021 · DOI: 10.1111/nph.17042 Loss of function of the chloroplast membrane K + /H + antiporters AtKEA1 and AtKEA2 alters the ROS and NO metabolism but promotes drought stress resilience.2021 · DOI: 10.1016/j.plaphy.2021.01.010 Loss of inner-envelope K+/H+ exchangers impairs plastid rRNA maturation and gene expression.2021 · DOI: 10.1093/plcell/koab123 Exogenous sucrose influences KEA1 and KEA2 to regulate abscisic acid-mediated primary root growth in Arabidopsis.2022 · DOI: 10.1016/j.plantsci.2022.111209

Rice

No hit for this species in the current source table.

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_005644 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction Biological Process

GO:0000138 Golgi trans cisterna Cellular Component

GO:0000139 Golgi membrane Cellular Component

GO:0005886 plasma membrane Cellular Component

GO:0009507 chloroplast Cellular Component

GO:0015386 potassium:proton antiporter activity Molecular Function

GO:0043495 protein-membrane adaptor activity Molecular Function

KEGG gene cross-reference

ath:AT2G19600

ath:AT5G11800

ath:AT5G51710

hsa:55002

mmu:234076

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

Open Annotation Module

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Golgi apparatus0.467

Rank 1 · TkA01G030790 · TK1151

Endoplasmic reticulum0.203

Rank 2 · TkA01G030790 · TK1151

Cytoplasm0.165

Rank 3 · TkA01G030790 · TK1151

Lysosome / Vacuole0.163

Rank 4 · TkA01G030790 · TK1151

Cell membrane0.111

Rank 5 · TkA01G030790 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF00999Na_H_Exchanger183-345 aa

PF29119F13C5_C228-241 aa

PF29119F13C5_C264-280 aa

PF29119F13C5_C321-340 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA01G030790	`PF00999`	Na_H_Exchanger	183	345	7.5e-34	117.9
TkA01G030790	`PF29119`	F13C5_C	228	241	3.9	8.0
TkA01G030790	`PF29119`	F13C5_C	264	280	3.9	8.0
TkA01G030790	`PF29119`	F13C5_C	321	340	3.9	8.0

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

Protein	Organism	Description	Identity	Database	Confidence
`B5X0N6`	Arabidopsis thaliana	sp\|B5X0N6\|KEA6_ARATH K(+) efflux antiporter 6	74.000%	Swiss-Prot	High
`Q9ZUN3`	Arabidopsis thaliana	sp\|Q9ZUN3\|KEA4_ARATH K(+) efflux antiporter 4	74.900%	Swiss-Prot	High
`Q8VYR9`	Arabidopsis thaliana	sp\|Q8VYR9\|KEA5_ARATH K(+) efflux antiporter 5	65.800%	Swiss-Prot	High
`O65272`	Arabidopsis thaliana	sp\|O65272\|KEA2_ARATH K(+) efflux antiporter 2, chloroplastic	36.500%	Swiss-Prot	Low
`Q9ZTZ7`	Arabidopsis thaliana	sp\|Q9ZTZ7\|KEA1_ARATH K(+) efflux antiporter 1, chloroplastic	35.800%	Swiss-Prot	Low

JBrowse

View in Genome Browser

Gene Card