Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

300 candidates match the current filter; 10 are shown per page (page 7 of 30). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA03G494300
TK1151: TkA03G494300;TkA03G495250
OH-1004: LXL04_010072
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:139365691-139367676
+
GO:0016114
LXL04_010112
TK1151: -
OH-1004: LXL04_010112
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtCoexpression CM104800.1:140379868-140381136
+
GO:0016740
TkA03G499170
TK1151: TkA03G499170
OH-1004: LXL04_010113
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:140390552-140392336
+
GO:0016740
TkA03G513450
TK1151: TkA03G513450
OH-1004: LXL04_010237
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:142678281-142681192
-
GO:0008299
TkA03G513520
TK1151: TkA03G513520
OH-1004: LXL04_010240
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:142694018-142697297
-
GO:0016740
TkA03G518320
TK1151: TkA03G518320;TkA03G518380
OH-1004: LXL04_010308
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:143958896-143961172
-
GO:0016114
TkAUNG096030
TK1151: TkAUNG096030;TkA08G216360
OH-1004: LXL04_010407
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:146186479-146187087
+
GO:0016114
TkA03G526770
TK1151: TkA03G526770
OH-1004: LXL04_010422
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:146347081-146349242
-
GO:0016740
LXL04_010559
TK1151: -
OH-1004: LXL04_010559
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:149048286-149049005
-
GO:0016740
LXL04_010560
TK1151: -
OH-1004: LXL04_010560
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtPPICoexpression CM104800.1:149049017-149049808
-
GO:0016740

TkA03G494300

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G494300;TkA03G495250
LocationCM104800.1:139365691-139367676 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

LXL04_010112

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104800.1:140379868-140381136 +
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA03G499170

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G499170
LocationCM104800.1:140390552-140392336 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA03G513450

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G513450
LocationCM104800.1:142678281-142681192 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA03G513520

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G513520
LocationCM104800.1:142694018-142697297 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA03G518320

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G518320;TkA03G518380
LocationCM104800.1:143958896-143961172 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkAUNG096030

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkAUNG096030;TkA08G216360
LocationCM104800.1:146186479-146187087 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkA03G526770

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G526770
LocationCM104800.1:146347081-146349242 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

LXL04_010559

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104800.1:149048286-149049005 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

LXL04_010560

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104800.1:149049017-149049808 -
EvidenceGOExpressionLocalizationSwiss-ProtPPICoexpression
Key evidenceGO:0016740

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.