Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Examples TkA01G624900 LXL04_000258

Download current filtered candidate TSV

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.

2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.

3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.

Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.

1Hardy rubber treeClick to view · 1 sources · trans-1,4-polyisoprene

Download current cross-species reference TSV

Species and material	Reference gene / sequence ID	Pathway step	Evidence and boundary	Source
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic roots	`EuIPI`AB041629.2IDI	Prenyl-donor metabolismTrans-polyisoprene precursor-supply reference	A_direct_genetic_experiment EuIPI overexpression was associated with higher trans-polyisoprene accumulation. Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.	10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2

StepPrenyl-donor metabolism · IDI

EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.

BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Source10.1186/1472-6750-12-78

Pathway Navigation And Candidate Distribution

MVA · Mevalonate pathway

High 40 · Medium 3 · Low 4 MEP · MEP pathway

High 23 · Medium 0 · Low 36 IPP/DMAPP/FPP · Prenyl-donor metabolism

271

High 141 · Medium 83 · Low 47 CPT/CPTL · Cis-prenyltransferase branch

High 0 · Medium 0 · Low 5 REF/SRPP · Rubber-particle proteins

High 0 · Medium 0 · Low 7 Rubber · Rubber biosynthesis candidates

288

High 1 · Medium 287 · Low 0 Terpenoid · Terpenoid metabolism

380

High 72 · Medium 107 · Low 201 Latex/root · Latex/root associated candidates

4466

High 231 · Medium 1284 · Low 2951

377 MVA/MEP and isoprenoid

Click to filter · High 204 · Medium 86 · Low 87 4466 Latex/root related candidates

Click to filter · High 231 · Medium 1284 · Low 2951 300 Rubber biosynthesis

Click to filter · High 1 · Medium 287 · Low 12 380 Terpenoid metabolism

Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

377 candidates match the current filter; 10 are shown per page (page 35 of 38). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene ID	Pathway/step	Confidence	Evidence layers	Location	Key evidence	Actions
`TkA02G461030` TK1151: TkA02G461030;TkA06G106550 OH-1004: LXL04_024809	MVA/MEP and isoprenoid Prenyl-donor metabolism	Low score 2	GOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104803.1:99330449-99332927 -	go:0004311 geranylgeranyl diphosphate synthase activity molecular_function	Gene Card Expression Proteome JBrowse
`TkAUNG022300` TK1151: TkAUNG022300;TkA07G311370 OH-1004: LXL04_026108	MVA/MEP and isoprenoid Prenyl-donor metabolism	Low score 2	GOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104803.1:121023339-121026178 +	go:1904629 response to diterpene biological_process	Gene Card Expression Proteome JBrowse
`TkAUNG081120` TK1151: TkAUNG081120 OH-1004: LXL04_026641	MVA/MEP and isoprenoid Prenyl-donor metabolism	Low score 2	GOExpressionLocalizationPfamSwiss-ProtPPI	CM104804.1:792921-794721 +	go:0010333 terpene synthase activity molecular_function	Gene Card Expression Proteome JBrowse
`TkA07G004590` TK1151: TkA07G004590 OH-1004: LXL04_026731	MVA/MEP and isoprenoid Mevalonate pathway	Low score 2	GOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104804.1:2108831-2122168 -	go:0047994 hydroxymethylglutaryl-coa hydrolase activity molecular_function	Gene Card Expression Proteome JBrowse
`TkA07G004620` TK1151: TkA07G004620 OH-1004: LXL04_026732	MVA/MEP and isoprenoid Mevalonate pathway	Low score 2	GOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104804.1:2123522-2130701 -	go:0047994 hydroxymethylglutaryl-coa hydrolase activity molecular_function	Gene Card Expression Proteome JBrowse
`TkA03G004450` TK1151: TkA03G004450;TkA03G006800;TkA03G289800;TkA06G000140;TkA07G098240 OH-1004: LXL04_027868	MVA/MEP and isoprenoid Prenyl-donor metabolism	Low score 2	GOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104804.1:25076337-25079206 +	go:1904629 response to diterpene biological_process	Gene Card Expression Proteome JBrowse
`TkA07G145940` TK1151: TkA07G145940 OH-1004: LXL04_028355	MVA/MEP and isoprenoid Prenyl-donor metabolism	Low score 2	GOExpressionLocalizationPfamSwiss-ProtCoexpression	CM104804.1:38855913-38859896 -	go:0051762 sesquiterpene biosynthetic process biological_process	Gene Card Expression Proteome JBrowse
`LXL04_028770` TK1151: - OH-1004: LXL04_028770	MVA/MEP and isoprenoid MEP pathway	Low score 2	FunctionExpressionLocalizationPfamSwiss-Prot	CM104804.1:62208142-62208729 +	lxl04_028770 similar to orf vi: transactivator/viroplasmin protein (figwort mosaic virus (strain dxs) ox=10650)	Gene Card Expression Proteome JBrowse
`TkA01G261850` TK1151: TkA01G261850;TkA05G224060;TkA06G055450;TkA07G211150 OH-1004: LXL04_028771	MVA/MEP and isoprenoid MEP pathway	Low score 2	FunctionExpressionLocalizationPfamSwiss-Prot	CM104804.1:62216392-62217318 +	lxl04_028771 similar to orf vi: transactivator/viroplasmin protein (figwort mosaic virus (strain dxs) ox=10650)	Gene Card Expression Proteome JBrowse
`TkA07G211250` TK1151: TkA07G211250 OH-1004: LXL04_028772	MVA/MEP and isoprenoid MEP pathway	Low score 2	FunctionExpressionLocalizationSwiss-Prot	CM104804.1:62237253-62238379 -	lxl04_028772 similar to orf vi: transactivator/viroplasmin protein (figwort mosaic virus (strain dxs) ox=10650)	Gene Card Expression Proteome JBrowse

`TkA02G461030`

MVA/MEP and isoprenoidPrenyl-donor metabolismLow · score 2

Source IDTkA02G461030;TkA06G106550

LocationCM104803.1:99330449-99332927 -

EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidencego:0004311 geranylgeranyl diphosphate synthase activity molecular_function

Gene Card Expression Proteome JBrowse

`TkAUNG022300`

MVA/MEP and isoprenoidPrenyl-donor metabolismLow · score 2

Source IDTkAUNG022300;TkA07G311370

LocationCM104803.1:121023339-121026178 +

EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidencego:1904629 response to diterpene biological_process

Gene Card Expression Proteome JBrowse

`TkAUNG081120`

MVA/MEP and isoprenoidPrenyl-donor metabolismLow · score 2

Source IDTkAUNG081120

LocationCM104804.1:792921-794721 +

EvidenceGOExpressionLocalizationPfamSwiss-ProtPPI

Key evidencego:0010333 terpene synthase activity molecular_function

Gene Card Expression Proteome JBrowse

`TkA07G004590`

MVA/MEP and isoprenoidMevalonate pathwayLow · score 2

Source IDTkA07G004590

LocationCM104804.1:2108831-2122168 -

EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidencego:0047994 hydroxymethylglutaryl-coa hydrolase activity molecular_function

Gene Card Expression Proteome JBrowse

`TkA07G004620`

MVA/MEP and isoprenoidMevalonate pathwayLow · score 2

Source IDTkA07G004620

LocationCM104804.1:2123522-2130701 -

EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidencego:0047994 hydroxymethylglutaryl-coa hydrolase activity molecular_function

Gene Card Expression Proteome JBrowse

`TkA03G004450`

MVA/MEP and isoprenoidPrenyl-donor metabolismLow · score 2

Source IDTkA03G004450;TkA03G006800;TkA03G289800;TkA06G000140;TkA07G098240

LocationCM104804.1:25076337-25079206 +

EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidencego:1904629 response to diterpene biological_process

Gene Card Expression Proteome JBrowse

`TkA07G145940`

MVA/MEP and isoprenoidPrenyl-donor metabolismLow · score 2

Source IDTkA07G145940

LocationCM104804.1:38855913-38859896 -

EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression

Key evidencego:0051762 sesquiterpene biosynthetic process biological_process

Gene Card Expression Proteome JBrowse

`LXL04_028770`

MVA/MEP and isoprenoidMEP pathwayLow · score 2

Source ID-

LocationCM104804.1:62208142-62208729 +

EvidenceFunctionExpressionLocalizationPfamSwiss-Prot

Key evidencelxl04_028770 similar to orf vi: transactivator/viroplasmin protein (figwort mosaic virus (strain dxs) ox=10650)

Gene Card Expression Proteome JBrowse

`TkA01G261850`

MVA/MEP and isoprenoidMEP pathwayLow · score 2

Source IDTkA01G261850;TkA05G224060;TkA06G055450;TkA07G211150

LocationCM104804.1:62216392-62217318 +

EvidenceFunctionExpressionLocalizationPfamSwiss-Prot

Key evidencelxl04_028771 similar to orf vi: transactivator/viroplasmin protein (figwort mosaic virus (strain dxs) ox=10650)

Gene Card Expression Proteome JBrowse

`TkA07G211250`

MVA/MEP and isoprenoidMEP pathwayLow · score 2

Source IDTkA07G211250

LocationCM104804.1:62237253-62238379 -

EvidenceFunctionExpressionLocalizationSwiss-Prot

Key evidencelxl04_028772 similar to orf vi: transactivator/viroplasmin protein (figwort mosaic virus (strain dxs) ox=10650)

Gene Card Expression Proteome JBrowse

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.