Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

300 candidates match the current filter; 10 are shown per page (page 29 of 30). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA04G415850
TK1151: TkA04G415850
OH-1004: LXL04_038305
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104807.1:36941482-36944078
-
GO:0016114
TkAUNG089850
TK1151: TkAUNG089850;TkA02G042480;TkA02G481170;TkA04G415960;TkA07G148450
OH-1004: LXL04_038308
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104807.1:36967663-36970360
-
GO:0016114
TkA04G426930
TK1151: TkA04G426930
OH-1004: LXL04_038416
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104807.1:40309786-40314624
+
GO:0008299
TkA04G442840
TK1151: TkA04G442840;TkA04G442850
OH-1004: LXL04_038568
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104807.1:44200431-44203018
-
GO:0016114
TkA04G452370
TK1151: TkA04G452370
OH-1004: LXL04_038637
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104807.1:46958088-46959776
-
GO:0016114
TkA04G471610
TK1151: TkA04G471610
OH-1004: LXL04_038850
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104807.1:51982891-51984621
-
GO:0016114
TkA04G219480
TK1151: TkA04G219480;TkA04G233160;TkA07G095350
OH-1004: LXL04_039326
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-Prot JAJTUU010000010.1:3030182-3033610
+
GO:0016740
TkA04G233150
TK1151: TkA04G233150;TkA04G235000
OH-1004: LXL04_039635
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-Prot JAJTUU010000020.1:218024-218830
+
GO:0016740
TkA01G556900
TK1151: TkA01G556900
OH-1004: LXL04_001167
Rubber biosynthesis
Rubber-particle proteins
Low
score 2
FunctionExpressionLocalizationSwiss-ProtPPICoexpression CM104799.1:21389679-21390694
-
lxl04_001167 similar to srpp: protein seed and root hair protective protein (arabidopsis thaliana ox=3702)
TkA01G411000
TK1151: TkA01G411000;TkA01G411040
OH-1004: LXL04_002917
Rubber biosynthesis
Rubber-particle proteins
Low
score 2
FunctionExpressionLocalizationSwiss-ProtPPICoexpression CM104799.1:61256237-61260119
-
lxl04_002917 similar to srpp: protein seed and root hair protective protein (arabidopsis thaliana ox=3702)

TkA04G415850

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G415850
LocationCM104807.1:36941482-36944078 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkAUNG089850

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkAUNG089850;TkA02G042480;TkA02G481170;TkA04G415960;TkA07G148450
LocationCM104807.1:36967663-36970360 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkA04G426930

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G426930
LocationCM104807.1:40309786-40314624 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA04G442840

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G442840;TkA04G442850
LocationCM104807.1:44200431-44203018 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA04G452370

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G452370
LocationCM104807.1:46958088-46959776 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkA04G471610

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G471610
LocationCM104807.1:51982891-51984621 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA04G219480

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G219480;TkA04G233160;TkA07G095350
LocationJAJTUU010000010.1:3030182-3033610 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidenceGO:0016740

TkA04G233150

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G233150;TkA04G235000
LocationJAJTUU010000020.1:218024-218830 +
EvidenceGOExpressionLocalizationSwiss-Prot
Key evidenceGO:0016740

TkA01G556900

Rubber biosynthesisRubber-particle proteinsLow · score 2
Source IDTkA01G556900
LocationCM104799.1:21389679-21390694 -
EvidenceFunctionExpressionLocalizationSwiss-ProtPPICoexpression
Key evidencelxl04_001167 similar to srpp: protein seed and root hair protective protein (arabidopsis thaliana ox=3702)

TkA01G411000

Rubber biosynthesisRubber-particle proteinsLow · score 2
Source IDTkA01G411000;TkA01G411040
LocationCM104799.1:61256237-61260119 -
EvidenceFunctionExpressionLocalizationSwiss-ProtPPICoexpression
Key evidencelxl04_002917 similar to srpp: protein seed and root hair protective protein (arabidopsis thaliana ox=3702)

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.