Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 199 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA07G362590
TK1151: TkA07G362590
OH-1004: LXL04_029955
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:103957405-103958634
-
go:0071472 cellular response to salt stress biological_process
TkA07G371840
TK1151: TkA07G371840
OH-1004: LXL04_030031
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:106096675-106098114
-
go:0006970 response to osmotic stress biological_process
TkA07G372820
TK1151: TkA07G372820;TkA07G372900
OH-1004: LXL04_030046
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:106333674-106336899
-
go:0016114 terpenoid biosynthetic process biological_process
LXL04_030047
TK1151: -
OH-1004: LXL04_030047
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:106380860-106381624
+
go:0016114 terpenoid biosynthetic process biological_process
TkA07G372950
TK1151: TkA07G372950
OH-1004: LXL04_030050
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:106413298-106414062
+
go:0016114 terpenoid biosynthetic process biological_process
LXL04_030052
TK1151: -
OH-1004: LXL04_030052
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:106440595-106442744
+
go:0016114 terpenoid biosynthetic process biological_process
TkA07G373540
TK1151: TkA07G373540
OH-1004: LXL04_030059
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:106561013-106575351
+
go:0006950 response to stress biological_process
TkA07G374010
TK1151: TkA07G374010
OH-1004: LXL04_030061
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:106686964-106688691
+
go:0006950 response to stress biological_process
LXL04_030062
TK1151: -
OH-1004: LXL04_030062
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:106690795-106693278
+
go:0006950 response to stress biological_process
LXL04_030066
TK1151: -
OH-1004: LXL04_030066
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:106883874-106885822
+
go:0006950 response to stress biological_process

TkA07G362590

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA07G362590
LocationCM104804.1:103957405-103958634 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0071472 cellular response to salt stress biological_process

TkA07G371840

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA07G371840
LocationCM104804.1:106096675-106098114 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA07G372820

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source IDTkA07G372820;TkA07G372900
LocationCM104804.1:106333674-106336899 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

LXL04_030047

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source ID-
LocationCM104804.1:106380860-106381624 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

TkA07G372950

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source IDTkA07G372950
LocationCM104804.1:106413298-106414062 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

LXL04_030052

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source ID-
LocationCM104804.1:106440595-106442744 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

TkA07G373540

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA07G373540
LocationCM104804.1:106561013-106575351 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006950 response to stress biological_process

TkA07G374010

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA07G374010
LocationCM104804.1:106686964-106688691 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006950 response to stress biological_process

LXL04_030062

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source ID-
LocationCM104804.1:106690795-106693278 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006950 response to stress biological_process

LXL04_030066

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source ID-
LocationCM104804.1:106883874-106885822 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006950 response to stress biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.