Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 17 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA05G430620
TK1151: TkA05G430620
OH-1004: LXL04_021856
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:138732491-138734833
+
go:0010311 lateral root formation biological_process
TkA05G448690
TK1151: TkA05G448690
OH-1004: LXL04_022167
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:145578780-145584241
-
go:0010015 root morphogenesis biological_process
TkA01G210210
TK1151: TkA01G210210;TkA05G449790;TkA06G063490;TkA06G063570
OH-1004: LXL04_022189
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:145855617-145864132
+
go:0010494 cytoplasmic stress granule cellular_component
TkA06G439560
TK1151: TkA06G439560
OH-1004: LXL04_022818
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:10224249-10226613
+
go:0006970 response to osmotic stress biological_process
TkA06G390560
TK1151: TkA06G390560
OH-1004: LXL04_023169
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:25551560-25554322
-
go:0010311 lateral root formation biological_process
TkA06G377200
TK1151: TkA06G377200
OH-1004: LXL04_023265
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:29248674-29251723
-
go:0009651 response to salt stress biological_process
TkA03G020930
TK1151: TkA03G020930;TkA06G185050
OH-1004: LXL04_024045
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:78597409-78598952
-
go:0009611 response to wounding biological_process
TkA06G170640
TK1151: TkA06G170640;TkA06G170650
OH-1004: LXL04_024169
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:83064244-83066226
+
go:0010102 lateral root morphogenesis biological_process
TkA06G155220
TK1151: TkA06G155220
OH-1004: LXL04_024317
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:87289496-87291923
-
go:0006970 response to osmotic stress biological_process
TkA06G077500
TK1151: TkA06G077500
OH-1004: LXL04_025166
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:107032679-107035254
-
go:0006950 response to stress biological_process

TkA05G430620

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA05G430620
LocationCM104802.1:138732491-138734833 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010311 lateral root formation biological_process

TkA05G448690

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA05G448690
LocationCM104802.1:145578780-145584241 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010015 root morphogenesis biological_process

TkA01G210210

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G210210;TkA05G449790;TkA06G063490;TkA06G063570
LocationCM104802.1:145855617-145864132 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010494 cytoplasmic stress granule cellular_component

TkA06G439560

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA06G439560
LocationCM104803.1:10224249-10226613 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA06G390560

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA06G390560
LocationCM104803.1:25551560-25554322 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010311 lateral root formation biological_process

TkA06G377200

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA06G377200
LocationCM104803.1:29248674-29251723 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA03G020930

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G020930;TkA06G185050
LocationCM104803.1:78597409-78598952 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkA06G170640

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA06G170640;TkA06G170650
LocationCM104803.1:83064244-83066226 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010102 lateral root morphogenesis biological_process

TkA06G155220

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA06G155220
LocationCM104803.1:87289496-87291923 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA06G077500

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA06G077500
LocationCM104803.1:107032679-107035254 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006950 response to stress biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.