Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

300 candidates match the current filter; 10 are shown per page (page 10 of 30). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA02G520890
TK1151: TkA02G520890
OH-1004: LXL04_013034
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:22823670-22831718
+
GO:0016114
TkA01G121600
TK1151: TkA01G121600;TkA02G490850
OH-1004: LXL04_013543
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:31254947-31258447
-
GO:0016740
TkA02G477560
TK1151: TkA02G477560
OH-1004: LXL04_013702
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:34380223-34381922
+
GO:0016740
TkA02G464040
TK1151: TkA02G464040
OH-1004: LXL04_013921
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:38088550-38092576
+
GO:0008299
TkA02G451880
TK1151: TkA02G451880
OH-1004: LXL04_014119
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:42283756-42285609
+
GO:0016740
TkA02G448690
TK1151: TkA02G448690
OH-1004: LXL04_014183
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:43288238-43290024
+
GO:0008299
LXL04_014538
TK1151: -
OH-1004: LXL04_014538
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-Prot CM104801.1:51953503-51954015
-
GO:0016114
TkA02G402670
TK1151: TkA02G402670
OH-1004: LXL04_014719
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:55486680-55489299
-
GO:0016114
TkA02G367060
TK1151: TkA02G367060;TkA03G396950
OH-1004: LXL04_015116
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:63939707-63943979
+
GO:0016740
LXL04_015581
TK1151: -
OH-1004: LXL04_015581
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:76526566-76530546
-
GO:0016114

TkA02G520890

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G520890
LocationCM104801.1:22823670-22831718 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkA01G121600

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G121600;TkA02G490850
LocationCM104801.1:31254947-31258447 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA02G477560

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G477560
LocationCM104801.1:34380223-34381922 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA02G464040

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G464040
LocationCM104801.1:38088550-38092576 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA02G451880

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G451880
LocationCM104801.1:42283756-42285609 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA02G448690

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G448690
LocationCM104801.1:43288238-43290024 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

LXL04_014538

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104801.1:51953503-51954015 -
EvidenceGOExpressionLocalizationSwiss-Prot
Key evidenceGO:0016114

TkA02G402670

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G402670
LocationCM104801.1:55486680-55489299 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA02G367060

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G367060;TkA03G396950
LocationCM104801.1:63939707-63943979 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

LXL04_015581

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104801.1:76526566-76530546 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.