Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

8 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT1JQ991925.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT2JQ991926.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT3JQ991927.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRubber-particle extraction and heterologous assaysTbSRPP1JQ991928.1SRPPREF/SRPP rubber-particle proteinsSmall rubber-particle proteinA_direct_experiment
TbSRPP1 is a direct experimental reference associated with rubber-particle formation.
External particle-protein evidence, not direct validation in T. kok-saghyz.
10.1111/tpj.13829Small rubber particle proteins from Taraxacum brevicorniculatum are associated with rubber particle formation
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbRTAKP763637.1RTALatex/root associatedRubber transferase activator referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbFDPS1KJ911908.1FDPSPrenyl-donor metabolismPrenyl-donor synthesis referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbFDPS2KJ911910.1FDPSPrenyl-donor metabolismPrenyl-donor synthesis referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbREFMF471639.1REFREF/SRPP rubber-particle proteinsRubber-particle protein referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records

Laticiferous dandelion · TbCPT1

Sequence IDJQ991925.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbCPT2

Sequence IDJQ991926.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbCPT3

Sequence IDJQ991927.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbSRPP1

Sequence IDJQ991928.1
StepREF/SRPP rubber-particle proteins · SRPP
EvidenceTbSRPP1 is a direct experimental reference associated with rubber-particle formation.
BoundaryExternal particle-protein evidence, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbRTA

Sequence IDKP763637.1
StepLatex/root associated · RTA
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbFDPS1

Sequence IDKJ911908.1
StepPrenyl-donor metabolism · FDPS
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbFDPS2

Sequence IDKJ911910.1
StepPrenyl-donor metabolism · FDPS
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbREF

Sequence IDMF471639.1
StepREF/SRPP rubber-particle proteins · REF
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 8 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA04G128060
TK1151: TkA04G128060
OH-1004: LXL04_035473
MVA/MEP and isoprenoid
Mevalonate pathway
High
score 14
FunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression CM104806.1:23243659-23245942
-
GO:0008299
TkA02G612530
TK1151: TkA02G612530;TkA04G266490
OH-1004: LXL04_037269
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 14
FunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression CM104807.1:4733087-4735352
-
GO:0045337
TkA04G267310
TK1151: TkA04G267310
OH-1004: LXL04_037275
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 14
FunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression CM104807.1:4911285-4916822
-
GO:0045337
TkA06G258190
TK1151: TkA06G258190
OH-1004: LXL04_037524
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 14
FunctionGOExpressionLocalizationSwiss-ProtCoexpression CM104807.1:13078769-13080159
+
GO:0045337
TkA04G336710
TK1151: TkA04G336710;TkA04G336720
OH-1004: LXL04_003623
MVA/MEP and isoprenoid
Mevalonate pathway
High
score 12
FunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:89563505-89564709
-
GO:0008299
TkA01G068410
TK1151: TkA01G068410;TkA02G316910
OH-1004: LXL04_005297
Latex/root related candidates
Latex/root associated candidates
High
score 12
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:159852677-159854016
+
go:0034599 cellular response to oxidative stress biological_process
TkA03G541850
TK1151: TkA03G541850
OH-1004: LXL04_010661
Terpenoid metabolism
Terpenoid metabolism
High
score 12
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:151028943-151030549
+
GO:0016102
LXL04_010868
TK1151: -
OH-1004: LXL04_010868
Latex/root related candidates
Latex/root associated candidates
High
score 12
GOExpressionLocalizationPfamSwiss-Prot CM104800.1:154482429-154482883
-
go:0009611 response to wounding biological_process
TkA02G464040
TK1151: TkA02G464040
OH-1004: LXL04_013921
MVA/MEP and isoprenoid
Mevalonate pathway
High
score 12
FunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:38088550-38092576
+
GO:0008299
TkAUNG096090
TK1151: TkAUNG096090;TkA01G533010;TkA02G062970
OH-1004: LXL04_017256
Latex/root related candidates
Latex/root associated candidates
High
score 12
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:144407820-144411075
-
go:0006970 response to osmotic stress biological_process

TkA04G128060

MVA/MEP and isoprenoidMevalonate pathwayHigh · score 14
Source IDTkA04G128060
LocationCM104806.1:23243659-23245942 -
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA02G612530

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 14
Source IDTkA02G612530;TkA04G266490
LocationCM104807.1:4733087-4735352 -
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0045337

TkA04G267310

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 14
Source IDTkA04G267310
LocationCM104807.1:4911285-4916822 -
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0045337

TkA06G258190

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 14
Source IDTkA06G258190
LocationCM104807.1:13078769-13080159 +
EvidenceFunctionGOExpressionLocalizationSwiss-ProtCoexpression
Key evidenceGO:0045337

TkA04G336710

MVA/MEP and isoprenoidMevalonate pathwayHigh · score 12
Source IDTkA04G336710;TkA04G336720
LocationCM104799.1:89563505-89564709 -
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA01G068410

Latex/root related candidatesLatex/root associated candidatesHigh · score 12
Source IDTkA01G068410;TkA02G316910
LocationCM104799.1:159852677-159854016 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0034599 cellular response to oxidative stress biological_process

TkA03G541850

Terpenoid metabolismTerpenoid metabolismHigh · score 12
Source IDTkA03G541850
LocationCM104800.1:151028943-151030549 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016102

LXL04_010868

Latex/root related candidatesLatex/root associated candidatesHigh · score 12
Source ID-
LocationCM104800.1:154482429-154482883 -
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidencego:0009611 response to wounding biological_process

TkA02G464040

MVA/MEP and isoprenoidMevalonate pathwayHigh · score 12
Source IDTkA02G464040
LocationCM104801.1:38088550-38092576 +
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkAUNG096090

Latex/root related candidatesLatex/root associated candidatesHigh · score 12
Source IDTkAUNG096090;TkA01G533010;TkA02G062970
LocationCM104801.1:144407820-144411075 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.