Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 197 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
LXL04_029390
TK1151: -
OH-1004: LXL04_029390
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:88945161-88950455
+
go:0016104 triterpenoid biosynthetic process biological_process
TkA08G039570
TK1151: TkA08G039570
OH-1004: LXL04_029392
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:88956590-88960762
-
go:0016104 triterpenoid biosynthetic process biological_process
TkA07G309590
TK1151: TkA07G309590;TkA07G309940
OH-1004: LXL04_029396
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:89056055-89060084
-
go:0016104 triterpenoid biosynthetic process biological_process
TkA01G021030
TK1151: TkA01G021030;TkA07G316120
OH-1004: LXL04_029452
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:90926799-90930812
+
go:0006970 response to osmotic stress biological_process
TkA07G313720
TK1151: TkA07G313720
OH-1004: LXL04_029467
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:91439496-91444766
-
go:0010078 maintenance of root meristem identity biological_process
TkA02G263550
TK1151: TkA02G263550;TkA07G320030
OH-1004: LXL04_029512
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:92676311-92679211
+
go:0009651 response to salt stress biological_process
TkA01G284630
TK1151: TkA01G284630;TkA02G388680;TkA03G113050;TkA06G225120;TkA06G427880
OH-1004: LXL04_029571
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationSwiss-ProtCoexpression CM104804.1:94464106-94465885
+
go:0009651 response to salt stress biological_process
LXL04_029590
TK1151: -
OH-1004: LXL04_029590
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:94924760-94926028
+
go:0016114 terpenoid biosynthetic process biological_process
TkA07G329440
TK1151: TkA07G329440;TkA07G329470;TkA07G330650;TkA07G330720
OH-1004: LXL04_029619
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:95586709-95588186
-
go:0006979 response to oxidative stress biological_process
TkA07G332660
TK1151: TkA07G332660
OH-1004: LXL04_029642
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:96140440-96145113
-
go:0009651 response to salt stress biological_process

LXL04_029390

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source ID-
LocationCM104804.1:88945161-88950455 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016104 triterpenoid biosynthetic process biological_process

TkA08G039570

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source IDTkA08G039570
LocationCM104804.1:88956590-88960762 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016104 triterpenoid biosynthetic process biological_process

TkA07G309590

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source IDTkA07G309590;TkA07G309940
LocationCM104804.1:89056055-89060084 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016104 triterpenoid biosynthetic process biological_process

TkA01G021030

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA01G021030;TkA07G316120
LocationCM104804.1:90926799-90930812 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA07G313720

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA07G313720
LocationCM104804.1:91439496-91444766 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010078 maintenance of root meristem identity biological_process

TkA02G263550

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA02G263550;TkA07G320030
LocationCM104804.1:92676311-92679211 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA01G284630

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA01G284630;TkA02G388680;TkA03G113050;TkA06G225120;TkA06G427880
LocationCM104804.1:94464106-94465885 +
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0009651 response to salt stress biological_process

LXL04_029590

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source ID-
LocationCM104804.1:94924760-94926028 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

TkA07G329440

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA07G329440;TkA07G329470;TkA07G330650;TkA07G330720
LocationCM104804.1:95586709-95588186 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkA07G332660

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA07G332660
LocationCM104804.1:96140440-96145113 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009651 response to salt stress biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.