Gene Card
Gene overview
cDNA / CDS / Protein Sequences
1658 bp · TkA08G132660|TK1151|cDNA
TTAACCTTTTAGCCCAAAGCATATTCCCCAGCTTTCTATATGCTCAGCTTTGATCGTCAATTCTTGGGAATTTCAGTCTCGATAAACTTTGTTCTAGCTCGATTGTCTTCCAATTCACTGATTCATTTCTTAGATTCACTTCTTTATACCTACAAATGAGACTTTTCATTCGATTTTTGGCACTGAAGCCTAGGTCTTGCCGCTAAATTATCTTCTTCCATGGCGATCAGAGGCGTACACTTCAAGTGGTACGATGGATT...
1221 bp · TkA08G132660|TK1151|CDS
ATGGCGATCAGAGGCGTACACTTCAAGTGGTACGATGGATTCTTTCTAATAATGCTTGCGTTTAGTATAGTTATGGTTCTATTGAGTTGGAGGCGTTACTATCTTTGTAAATTTCCATTGCATCTGTGGATAGTGGTTGATTATAGTGCTGTGTTTGTTTTTCGCCTCTTAATGTTTGTAGATAATGGTCTTGCAGCTGGAATGGGACTGGATTATGGTAGGCGGCAAAGAGATGTTTGTTTTTATGGAAGAGTAGTAGT...
Protein
Download Protein FASTA406 aa · TkA08G132660|TK1151|PROTEIN
MAIRGVHFKWYDGFFLIMLAFSIVMVLLSWRRYYLCKFPLHLWIVVDYSAVFVFRLLMFVDNGLAAGMGLDYGRRQRDVCFYGRVVVLSILYVVLYPFLWAWSVTGSIWFSYAHACLPEKNQKWGFLVWLIFSYCGLVCLAVYSVNKWLRRRKAHFERVQQGIPISGISEYGVLVDMIRLPDWVFESAAQEMRVMENDATPHHPGLYLSDAQRQAVEILVQELPLFSLKAVPTDCSDCPICLEEFHVEDEVRGLPCAHNF...
Flanking Sequence Download
Sequence orientation and download details
Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.
ID Mapping
| Input ID | TkA08G132660 |
|---|---|
| TK1151 ID | TkA08G132660 |
| OH-1004 ID | LXL04_031851 |
| Relationship / confidence | Multi Source To Oh1004 / Complex relationship |
| Protein identity (%) | 99.700 |
| Protein coverage (%) | TK1151 92.365 / OH-1004 87.007Coverage and evidenceCoverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation. |
| Source version | TK1151 / GWHBCHF00000000 |
SNP / Indel variants and carrier samplesCRA009020 · TK1151
Expand to load variant records for this gene.
Basic Information and Functional Annotation
| Gene ID | TkA08G132660 | ||||||
|---|---|---|---|---|---|---|---|
| Location | Chr08:34463195-34469011 (+) | ||||||
| Description | Similar to SIS3: E3 ubiquitin-protein ligase SIS3 | ||||||
| Arabidopsis / Rice Reference Genes and Papers |
Download references for this gene Arabidopsis
RiceNo hit for this species in the current source table. | ||||||
| Functional annotation source | View annotation sourcesFunctional annotation source: OH1004 · | ||||||
| GO annotations (OH1004 source) | GO:0006511 ubiquitin-dependent protein catabolic process Biological Process GO:0009793 embryo development ending in seed dormancy Biological Process GO:0010182 sugar mediated signaling pathway Biological Process GO:0016567 protein ubiquitination Biological Process GO:0031647 regulation of protein stability Biological Process GO:0043409 negative regulation of MAPK cascade Biological Process GO:0071466 cellular response to xenobiotic stimulus Biological Process GO:0005634 nucleus Cellular Component GO:0005737 cytoplasm Cellular Component GO:0005739 mitochondrion Cellular Component GO:0005770 late endosome Cellular Component GO:0005783 endoplasmic reticulum Cellular Component | ||||||
| KEGG gene cross-reference | ath:AT2G18650 ath:AT3G03550 ath:AT3G47990 ath:AT5G57750 mmu:67702 These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene. |
Gene expression
View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.
Data sources and gene correspondence
Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.
Subcellular Localization Top 5
Computational predictions or homology annotations below do not replace localization experiments.
LocPro · Direct prediction · Computational prediction, not experimental localization
Predicted Functional Domains
Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.
PF26753SIS3_N11-161 aaPF11674DUF327014-29 aaPF11674DUF327074-114 aaPF07114TMEM12676-128 aaPF03756AfsA173-220 aaPF13639zf-RING_2237-279 aaPF17123zf-RING_11237-265 aaPF14634zf-RING_5237-279 aa| Gene ID | Domain ID | Domain Name | Start aa | End aa | E-value | Score |
|---|---|---|---|---|---|---|
| TkA08G132660 | PF26753 | SIS3_N | 11 | 161 | 2e-64 | 216.8 |
| TkA08G132660 | PF11674 | DUF3270 | 14 | 29 | 0.092 | 13.5 |
| TkA08G132660 | PF11674 | DUF3270 | 74 | 114 | 0.092 | 13.5 |
| TkA08G132660 | PF07114 | TMEM126 | 76 | 128 | 0.025 | 14.7 |
| TkA08G132660 | PF03756 | AfsA | 173 | 220 | 0.038 | 14.4 |
| TkA08G132660 | PF13639 | zf-RING_2 | 237 | 279 | 2.4e-14 | 54.0 |
| TkA08G132660 | PF17123 | zf-RING_11 | 237 | 265 | 8.5e-10 | 38.9 |
| TkA08G132660 | PF14634 | zf-RING_5 | 237 | 279 | 0.0002 | 22.0 |
| TkA08G132660 | PF13920 | zf-C3HC4_3 | 237 | 281 | 1.0 | 9.9 |
| TkA08G132660 | PF13445 | zf-RING_UBOX | 238 | 276 | 4.3e-08 | 33.7 |
| TkA08G132660 | PF00097 | zf-C3HC4 | 238 | 278 | 1.2e-07 | 32.2 |
| TkA08G132660 | PF13923 | zf-C3HC4_2 | 238 | 278 | 1.4e-07 | 31.9 |
| TkA08G132660 | PF12861 | zf-ANAPC11 | 251 | 281 | 0.0034 | 18.1 |
| TkA08G132660 | PF12678 | zf-rbx1 | 253 | 279 | 2.3e-05 | 25.3 |
Arabidopsis / Rice Protein Homology
Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.
| Protein | Organism | Description | Identity | Database | Confidence |
|---|---|---|---|---|---|
Q8GYT9 | Arabidopsis thaliana | sp|Q8GYT9|SIS3_ARATH E3 ubiquitin-protein ligase SIS3 | 60.600% | Swiss-Prot | High |