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Gene Card

Enter a TK1151 or OH-1004 gene ID to view sequences, annotations and analyses in the corresponding reference genome.
Flanking length, max 10000 bp

Gene overview

TkA08G107510
Reference: TK1151 Chr: Chr08 Coordinates: 27952788-27955170 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

1557 bp · TkA08G107510|TK1151|cDNA

CTTCGGCAAATCCATTTCTTGCAAAATGGAATCGAAAGACTTTTGAAAACAGAGTACAAGACTTCCACTAAACCTAGGGTTACGTTGGGAAATCAGTGCAAGACTTTGACTTGTACCCCGTAGTTTCGAATTCGAGTTCAAATTTTGGGAAATCAGCTCAACTTCCACCTGTGGCTTCTGAATCGAGTTCCAGGGAGGCATATAATATACGCCAATTGGAACGCAGCCAGGACAAAATTAAAGGAAGGCAACAAAATCCT...

981 bp · TkA08G107510|TK1151|CDS

ATGGCGGATCTCGCATACCTTGCTCTTCTCTCACTTGTTCCAATCGTCTTCCTCGTCTTCCTGAAATTCATCCTCCGTCCTCACCCAATGAAAATTCCGATCAAATCCCGCCACGTCATGATCACCGGCGGGTCCAGCGGCATCGGCCTAGCTCTAGCCCACCAAGCCGCCGCCGAAGGTGCTCGCGTCACCATCTTAGCACGTAACCAAGAGAGGCTCGAGGAAGCCAAAGCCTCCATCCGCCTCTCAACCGGCATAGA...

326 aa · TkA08G107510|TK1151|PROTEIN

MADLAYLALLSLVPIVFLVFLKFILRPHPMKIPIKSRHVMITGGSSGIGLALAHQAAAEGARVTILARNQERLEEAKASIRLSTGIDVGIVSADVCDFEAVKEAVETVGPIDILICNQGVFVAQELDNQDIKDIRGMIDINLIGSFNLVKAALPGMKNRTDRKPVSIAFMSSQAGQVGIYGYTAYSASKFGLRGLAEALQHEVISDNIHVSLIFPPDTDTPGLIEENKNKPRVTSIIAASSGAMKADEVAKKAWDGIKSG...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

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ID Mapping

Input IDTkA08G107510
TK1151 IDTkA08G107510
OH-1004 IDLXL04_031450
Relationship / confidenceMulti Source To Oh1004 / Complex relationship
Protein identity (%)100.000
Protein coverage (%)TK1151 100.000 / OH-1004 100.000
Coverage and evidence

Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.

Source versionTK1151 / GWHBCHF00000000
SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene IDTkA08G107510
LocationChr08:27952788-27955170 (-)
DescriptionSimilar to TSC10A: 3-dehydrosphinganine reductase TSC10A
Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene IDPossible functionPapers / DOI
At3g06060 Catalyzes the reduction of 3'-oxosphinganine (3- ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.
At5g19200 Catalyzes the reduction of 3'-oxosphinganine (3- ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.

Rice

No hit for this species in the current source table.

Functional annotation source
View annotation sources

Functional annotation source: OH1004 · LXL04_031450 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)
GO:0006666 3-keto-sphinganine metabolic process Biological Process
GO:0006686 sphingomyelin biosynthetic process Biological Process
GO:0006688 glycosphingolipid biosynthetic process Biological Process
GO:0030148 sphingolipid biosynthetic process Biological Process
GO:0046513 ceramide biosynthetic process Biological Process
GO:0005615 extracellular space Cellular Component
GO:0005783 endoplasmic reticulum Cellular Component
GO:0005789 endoplasmic reticulum membrane Cellular Component
GO:0009507 chloroplast Cellular Component
GO:0016020 membrane Cellular Component
GO:0098554 cytoplasmic side of endoplasmic reticulum membrane Cellular Component
GO:0047560 3-dehydrosphinganine reductase activity Molecular Function
KEGG gene cross-reference
ath:AT3G06060
ath:AT5G19200
hsa:2531
mmu:70750
These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Endoplasmic reticulum0.716
Rank 1 · TkA08G107510 · TK1151
Cytoplasm0.111
Rank 2 · TkA08G107510 · TK1151
Mitochondrion0.088
Rank 3 · TkA08G107510 · TK1151
Golgi apparatus0.079
Rank 4 · TkA08G107510 · TK1151
Nucleus0.078
Rank 5 · TkA08G107510 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF18306LDcluster435-87 aa
PF12242Eno-Rase_NADH_b35-59 aa
PF05368NmrA37-129 aa
PF00106adh_short38-229 aa
PF04321RmlD_sub_bind38-110 aa
PF08659KR39-200 aa
PF01370Epimerase39-172 aa
PF02719Polysacc_synt_239-110 aa
Gene IDDomain IDDomain NameStart aaEnd aaE-valueScore
TkA08G107510PF18306LDcluster435870.02215.1
TkA08G107510PF12242Eno-Rase_NADH_b35590.09813.1
TkA08G107510PF05368NmrA371290.003717.6
TkA08G107510PF00106adh_short382296.5e-45153.7
TkA08G107510PF04321RmlD_sub_bind381100.05613.2
TkA08G107510PF08659KR392004.9e-1143.6
TkA08G107510PF01370Epimerase391721.3e-0732.0
TkA08G107510PF02719Polysacc_synt_2391100.1811.7
TkA08G107510PF16363GDP_Man_Dehyd401530.001418.9
TkA08G107510PF04127DFP41710.311.5
TkA08G107510PF13460NAD_binding_10431171.8e-0525.4
TkA08G107510PF03435Sacchrp_dh_NADP441080.08214.0
TkA08G107510PF02558ApbA441150.2211.9
TkA08G107510PF13561adh_short_C2462337e-2795.2
TkA08G107510PF03807F420_oxidored46880.0814.3
TkA08G107510PF00107ADH_zinc_N47920.007816.9

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

ProteinOrganismDescriptionIdentityDatabaseConfidence
Q0WRJ2Arabidopsis thalianasp|Q0WRJ2|KDSRA_ARATH 3-dehydrosphinganine reductase TSC10A62.000%Swiss-ProtHigh
F4JZN6Arabidopsis thalianasp|F4JZN6|KDSRB_ARATH 3-dehydrosphinganine reductase TSC10B60.200%Swiss-ProtHigh

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