TkA08G045300 | RubberDandelionOmics

Gene overview

TkA08G045300

Reference: TK1151 Chr: Chr08 Coordinates: 11563768-11565518 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

1301 bp · TkA08G045300|TK1151|cDNA

GCCTTTTGTATGATCTCTCTGTTTATTTTAAGATCATAATCAAAAGTTCCTAATAGTAAGTCAAACTCAGAAATTCGAACCTCCTTCAAACAGCATACGTCCTCTTTGCTTAAATATTTGTAATCGGCCTGCTGGTGTAATGATCTGAAGCCGAAAACAGATCTGTTCGCTCAGATTGTAATTCGTCTTGTTTCCAGTTACGTAGTCCCGATTTCCGAAGGTTTTATAAAAAAAATTAGATGGAACATCAACATGTTGCG...

CDS

Download CDS FASTA

1062 bp · TkA08G045300|TK1151|CDS

ATGGAACATCAACATGTTGCGATTCCAATTTCTGTCGCAGATCACCGTCTTTCAGAAGTAGAGATGCTACCAAAAGCCTCATGTGATCGTTGCTGCTATTTCTCTAAGCAAGAACATAATGTTTCCGACTCCAGATCTACAGCCAAGCTCAGTGGACTAATGTTCTTCTACGTAATCGTAATGGCAGTTGAGATTATCGGAGGTTTAAAATCTAATAGTTTAGCGGTTCTTTCAGATGCGGCTCATTTACTCACCGACAT...

Protein

Download Protein FASTA

354 aa · TkA08G045300|TK1151|PROTEIN

MEHQHVAIPISVADHRLSEVEMLPKASCDRCCYFSKQEHNVSDSRSTAKLSGLMFFYVIVMAVEIIGGLKSNSLAVLSDAAHLLTDIGGFSISLIIVWASVGKSTPRQSFGFSRIEVLGALLSVQMIWIISGYLVFEAIKRIVHKQSDVNGGLMFAISAFGFVINLIMVIWLGHGHSHGHGHDHSHGHDHDHGHSHVNEEEGTNLVVSTSNGKKAAMNINIEGVYLHVISDMIQSIGVMIAGLVIWVKPEWLIVDLICTL...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA08G045300`
TK1151 ID	TkA08G045300
OH-1004 ID	LXL04_017850
Relationship / confidence	Rbh High Identity Coverage Synteny / Strict
Protein identity (%)	95.900
Protein coverage (%)	TK1151 100.000 / OH-1004 93.455 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

Open Full ID Mapping

SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene ID TkA08G045300

Location Chr08:11563768-11565518 (-)

Description Similar to MTPB: Metal tolerance protein B

Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At2g29410`	Involved in sequestration of excess zinc in the cytoplasm into vacuoles to maintain zinc homeostasis.	No verified direct reference in this release
`At2g46800`	Mediates zinc accumulation in roots and confers resistance to zinc.	Zinc transporter of Arabidopsis thaliana AtMTP1 is localized to vacuolar membranes and implicated in zinc homeostasis.2004 · DOI: 10.1093/pcp/pci015 A mutant strain Arabidopsis thaliana that lacks vacuolar membrane zinc transporter MTP1 revealed the latent tolerance to excessive zinc.2009 · DOI: 10.1093/pcp/pcp067 A mutation in the Arabidopsis thaliana cell wall biosynthesis gene pectin methylesterase 3 as well as its aberrant expression cause hypersensitivity specifically to Zn.2013 · DOI: 10.1111/tpj.12279
`At3g58810`	Involved in sequestration of excess zinc in the cytoplasm into vacuoles to maintain zinc homeostasis.	The Arabidopsis metal tolerance protein AtMTP3 maintains metal homeostasis by mediating Zn exclusion from the shoot under Fe deficiency and Zn oversupply.2006 · DOI: 10.1111/j.1365-313x.2006.02746.x
`At3g61940`	Involved in sequestration of excess zinc in the cytoplasm into vacuoles to maintain zinc homeostasis.	No verified direct reference in this release

Rice

Reference gene ID	Possible function	Papers / DOI
`Os05g0128400`	Involved in sequestration of excess zinc in the cytoplasm into vacuoles to maintain zinc homeostasis.	No verified direct reference in this release

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_017850 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0006829 zinc ion transport Biological Process

GO:0006882 intracellular zinc ion homeostasis Biological Process

GO:0010038 response to metal ion Biological Process

GO:0010043 response to zinc ion Biological Process

GO:0010312 detoxification of zinc ion Biological Process

GO:0030001 metal ion transport Biological Process

GO:0071577 zinc ion transmembrane transport Biological Process

GO:0000325 plant-type vacuole Cellular Component

GO:0005737 cytoplasm Cellular Component

GO:0005773 vacuole Cellular Component

GO:0005774 vacuolar membrane Cellular Component

GO:0005789 endoplasmic reticulum membrane Cellular Component

KEGG gene cross-reference

ath:AT2G29410

ath:AT2G46800

ath:AT3G58810

ath:AT3G61940

dosa:Os05g0128400

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

Open Annotation Module

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Lysosome / Vacuole0.393

Rank 1 · TkA08G045300 · TK1151

Golgi apparatus0.221

Rank 2 · TkA08G045300 · TK1151

Cytoplasm0.219

Rank 3 · TkA08G045300 · TK1151

Cell membrane0.182

Rank 4 · TkA08G045300 · TK1151

Endoplasmic reticulum0.178

Rank 5 · TkA08G045300 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF01545Cation_efflux55-282 aa

PF14654Epiglycanin_C151-199 aa

PF04592SelP_N174-204 aa

PF10986ZrgA176-196 aa

PF14654Epiglycanin_C252-273 aa

PF16916ZT_dimer286-345 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA08G045300	`PF01545`	Cation_efflux	55	282	1.6e-37	130.0
TkA08G045300	`PF14654`	Epiglycanin_C	151	199	0.041	14.8
TkA08G045300	`PF04592`	SelP_N	174	204	5.7	7.0
TkA08G045300	`PF10986`	ZrgA	176	196	0.5	11.1
TkA08G045300	`PF14654`	Epiglycanin_C	252	273	0.041	14.8
TkA08G045300	`PF16916`	ZT_dimer	286	345	2.8e-07	31.1

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

Protein	Organism	Description	Identity	Database	Confidence
`Q6DBM8`	Arabidopsis thaliana	sp\|Q6DBM8\|MTPB_ARATH Metal tolerance protein B	54.900%	Swiss-Prot	High
`Q9ZT63`	Arabidopsis thaliana	sp\|Q9ZT63\|MTP1_ARATH Metal tolerance protein 1	45.800%	Swiss-Prot	Medium
`Q9LXS1`	Arabidopsis thaliana	sp\|Q9LXS1\|MTPA2_ARATH Metal tolerance protein A2	46.100%	Swiss-Prot	Medium
`Q9M271`	Arabidopsis thaliana	sp\|Q9M271\|MTPA1_ARATH Metal tolerance protein A1	46.400%	Swiss-Prot	Medium
`Q688R1`	Oryza sativa subsp. japonica	sp\|Q688R1\|MTP1_ORYSJ Metal tolerance protein 1	44.100%	Swiss-Prot	Medium

JBrowse

View in Genome Browser

Gene Card