TkA07G144630 | RubberDandelionOmics

Gene overview

TkA07G144630

Reference: TK1151 Chr: Chr07 Coordinates: 37355949-37359731 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

2836 bp · TkA07G144630|TK1151|cDNA

AAAAGAGTTAGAAATGTATATTTTGAAATTCGTAGCCGTTATCCCTTTTGACACCCACAAGGCCACAACAATGTTCCAACATCCTCCTTTCTTGTTCACTTACTCCCGCCACTTCCTACGCCGCCGCCACGCCGGCCACCACCTATCAACACCGCCTATTCGTCACCGTTTCCTCTCAACTATCACACACACGCTTTCACACCCTATCTATACCATATGGGCCGCCAACACTGGTCTTGGCAAAACCCTCGTTTCCACCG...

CDS

Download CDS FASTA

1326 bp · TkA07G144630|TK1151|CDS

ATGTATATTTTGAAATTCGTAGCCGTTATCCCTTTTGACACCCACAAGGCCACAACAATGTTCCAACATCCTCCTTTCTTGTTCACTTACTCCCGCCACTTCCTACGCCGCCGCCACGCCGGCCACCACCTATCAACACCGCCTATTCGTCACCGTTTCCTCTCAACTATCACACACACGCTTTCACACCCTATCTATACCATATGGGCCGCCAACACTGGTCTTGGCAAAACCCTCGTTTCCACCGGCCTCGCCGCCTC...

Protein

Download Protein FASTA

441 aa · TkA07G144630|TK1151|PROTEIN

MYILKFVAVIPFDTHKATTMFQHPPFLFTYSRHFLRRRHAGHHLSTPPIRHRFLSTITHTLSHPIYTIWAANTGLGKTLVSTGLAASSLHSSSPSPSKLVYIKPLQTGFPLDSDSAFIYRKVPQILLHRNPQSTLLASNQTLNVSVPAAKLKFGNNFSEEGQSSKNGFEASGYYEERKLGIGEEVQPELICKTMYAWKEAISPHLAAEREGSNVEDSDVLVMLKKCLETGIGSKGDERTTVLCLVETAGGVASPGSTGSL...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA07G144630`
TK1151 ID	TkA07G144630
OH-1004 ID	LXL04_028340
Relationship / confidence	Sequence Supported Annotation Or Model Conflict / Review
Protein identity (%)	98.800
Protein coverage (%)	TK1151 95.465 / OH-1004 48.897 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

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SNP / Indel variants and carrier samplesCRA009020 · TK1151

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Basic Information and Functional Annotation

Gene ID TkA07G144630

Location Chr07:37355949-37359731 (-)

Description Similar to BIO3-BIO1: Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial

Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At5g57590`	Bifunctional enzyme that catalyzes two different reactions involved in the biotin biosynthesis.	The role of biotin in regulating 3-methylcrotonyl-coenzyme a carboxylase expression in Arabidopsis.2003 · DOI: 10.1104/pp.013243 Arrested Embryos from the bio1 Auxotroph of Arabidopsis thaliana Contain Reduced Levels of Biotin.1990 · DOI: 10.1104/pp.93.3.1162 A bifunctional locus (BIO3-BIO1) required for biotin biosynthesis in Arabidopsis.2008 · DOI: 10.1104/pp.107.107409 Biochemical and structural characterization of the Arabidopsis bifunctional enzyme dethiobiotin synthetase-diaminopelargonic acid aminotransferase: evidence for substrate channeling in biotin synthesis.2012 · DOI: 10.1105/tpc.112.097675 SUCROSE TRANSPORTER 5 supplies Arabidopsis embryos with biotin and affects triacylglycerol accumulation.2013 · DOI: 10.1111/tpj.12037 An embryo-lethal mutant of Arabidopsis thaliana is a biotin auxotroph.1989 · DOI: 10.1016/s0012-1606(89)80047-8 Complementation of an Arabidopsis thaliana biotin auxotroph with an Escherichia coli biotin biosynthetic gene.1996 · DOI: 10.1007/bf02172516

Rice

Reference gene ID	Possible function	Papers / DOI
`Os08g0245400`	Bifunctional enzyme that catalyzes two different reactions involved in the biotin biosynthesis.	No verified direct reference in this release

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_028340 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0009102 biotin biosynthetic process Biological Process

GO:0005737 cytoplasm Cellular Component

GO:0005739 mitochondrion Cellular Component

GO:0005759 mitochondrial matrix Cellular Component

GO:0000287 magnesium ion binding Molecular Function

GO:0004015 adenosylmethionine-8-amino-7-oxononanoate transaminase activity Molecular Function

GO:0004141 dethiobiotin synthase activity Molecular Function

GO:0005524 ATP binding Molecular Function

GO:0030170 pyridoxal phosphate binding Molecular Function

GO:0042803 protein homodimerization activity Molecular Function

KEGG gene cross-reference

ani:ANIA_06644

ath:AT5G57590

dosa:Os08g0245400

hin:HI_1554

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

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Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Mitochondrion0.729

Rank 1 · TkA07G144630 · TK1151

Cytoplasm0.133

Rank 2 · TkA07G144630 · TK1151

Plastid0.110

Rank 3 · TkA07G144630 · TK1151

Nucleus0.092

Rank 4 · TkA07G144630 · TK1151

Peroxisome0.047

Rank 5 · TkA07G144630 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF00270DEAD67-105 aa

PF13500AAA_2668-125 aa

PF13500AAA_26189-334 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA07G144630	`PF00270`	DEAD	67	105	0.38	11.2
TkA07G144630	`PF13500`	AAA_26	68	125	6.1e-14	53.0
TkA07G144630	`PF13500`	AAA_26	189	334	6.1e-14	53.0

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

Protein	Organism	Description	Identity	Database	Confidence
`B0F481`	Arabidopsis thaliana	sp\|B0F481\|BIODA_ARATH Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial	56.400%	Swiss-Prot	High
`Q6ZKV8`	Oryza sativa subsp. japonica	sp\|Q6ZKV8\|BIODA_ORYSJ Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial	52.700%	Swiss-Prot	High

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