TkA04G401470 | RubberDandelionOmics

Gene overview

TkA04G401470

Reference: TK1151 Chr: Chr04 Coordinates: 100950900-100952033 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

1134 bp · TkA04G401470|TK1151|cDNA

ATGGGGTGGACTAGAGGCCCTGTTCTTGGCCGTGGCTCCTCCGCCACCGTCTCATCCGCCACCTCCACCTCCGGCGACGTTTTTGCCGTCAAGTCTATGGAGTTTTCCAAAGCAGAGAGCTTGCGAAAGGAACAACGTTTTTTGTCCGTTTTGAGTAGTCCTTATGTCGTGAGTTACAGAGGGTGTGATGTTAGTAAAGAAGATAACAAGATGGTGTACAATGTTCTGATGGAGTGTATGCCTTTTGGTTCGATTGTTGA...

CDS

Download CDS FASTA

1134 bp · TkA04G401470|TK1151|CDS

ATGGGGTGGACTAGAGGCCCTGTTCTTGGCCGTGGCTCCTCCGCCACCGTCTCATCCGCCACCTCCACCTCCGGCGACGTTTTTGCCGTCAAGTCTATGGAGTTTTCCAAAGCAGAGAGCTTGCGAAAGGAACAACGTTTTTTGTCCGTTTTGAGTAGTCCTTATGTCGTGAGTTACAGAGGGTGTGATGTTAGTAAAGAAGATAACAAGATGGTGTACAATGTTCTGATGGAGTGTATGCCTTTTGGTTCGATTGTTGA...

Protein

Download Protein FASTA

377 aa · TkA04G401470|TK1151|PROTEIN

MGWTRGPVLGRGSSATVSSATSTSGDVFAVKSMEFSKAESLRKEQRFLSVLSSPYVVSYRGCDVSKEDNKMVYNVLMECMPFGSIVDVVNGRNGGGLKSSEIGRYTREIVRGVEYLHSRGVVHCDIKGRNVLIDESGAKIGDFGCAKWVDEVAPISGTPMFMAPEVARGEEQGFPADVWAVGCTVIEMATGGSPWVNVNDAVSVLYRIAFSGEIPEIPEEFSDKGKDFIKKCLIRDPRERWTAKQLLNHPYLQQFDDNSN...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA04G401470`
TK1151 ID	TkA04G401470
OH-1004 ID	LXL04_038177
Relationship / confidence	Multi Source To Oh1004 / Complex relationship
Protein identity (%)	100.000
Protein coverage (%)	TK1151 100.000 / OH-1004 100.000 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

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SNP / Indel variants and carrier samplesCRA009020 · TK1151

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Basic Information and Functional Annotation

Gene ID TkA04G401470

Location Chr04:100950900-100952033 (-)

Description Similar to MAPKKK18: Mitogen-activated protein kinase kinase kinase 18

Arabidopsis / Rice Reference Genes and Papers

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Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At1g05100`	Component of the abscisic acid (ABA) signaling pathway that acts as ABA signal transducer in the context of abiotic stresses.	An abscisic acid inducible Arabidopsis MAPKKK, MAPKKK18 regulates leaf senescence via its kinase activity.2015 · DOI: 10.1007/s11103-015-0295-0 Arabidopsis ABA-Activated Kinase MAPKKK18 is Regulated by Protein Phosphatase 2C ABI1 and the Ubiquitin-Proteasome Pathway.2015 · DOI: 10.1093/pcp/pcv146
`At2g32510`	Component of the abscisic acid (ABA) signaling pathway that may act as ABA signal transducer in the context of abiotic stresses.	No verified direct reference in this release
`At3g50310`	Mitogen-activated protein kinase kinase (MAPKK) that phosphorylates both MKK3 and MPK18 and regulate two separate signaling pathways involved in root microtubule functions.	Arabidopsis MKKK20 is involved in osmotic stress response via regulation of MPK6 activity.2012 · DOI: 10.1007/s00299-011-1157-0 AIK1, A Mitogen-Activated Protein Kinase, Modulates Abscisic Acid Responses through the MKK5-MPK6 Kinase Cascade.2017 · DOI: 10.1104/pp.16.01386 The Arabidopsis Mitogen-Activated Protein Kinase Kinase Kinase 20 (MKKK20) Acts Upstream of MKK3 and MPK18 in Two Separate Signaling Pathways Involved in Root Microtubule Functions.2017 · DOI: 10.3389/fpls.2017.01352
`At1g54960`	Involved in cortical microtubules organization and stabilization by regulating the phosphorylation state of microtubule- associated proteins such as MAP65-1.	Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization.2010 · DOI: 10.1105/tpc.109.071746

Rice

No hit for this species in the current source table.

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_038177 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0000302 response to reactive oxygen species Biological Process

GO:0006468 protein phosphorylation Biological Process

GO:0006970 response to osmotic stress Biological Process

GO:0007165 signal transduction Biological Process

GO:0009409 response to cold Biological Process

GO:0009414 response to water deprivation Biological Process

GO:0009651 response to salt stress Biological Process

GO:0009653 anatomical structure morphogenesis Biological Process

GO:0009737 response to abscisic acid Biological Process

GO:0009738 abscisic acid-activated signaling pathway Biological Process

GO:0009789 positive regulation of abscisic acid-activated signaling pathway Biological Process

GO:0010029 regulation of seed germination Biological Process

KEGG gene cross-reference

ath:AT1G05100

ath:AT1G54960

ath:AT2G32510

ath:AT3G50310

ddi:DDB_G0283265

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

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Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Nucleus0.756

Rank 1 · TkA04G401470 · TK1151

Cytoplasm0.303

Rank 2 · TkA04G401470 · TK1151

Cell membrane0.060

Rank 3 · TkA04G401470 · TK1151

Endoplasmic reticulum0.038

Rank 4 · TkA04G401470 · TK1151

Plastid0.026

Rank 5 · TkA04G401470 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

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Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF00069Pkinase5-252 aa

PF07714PK_Tyr_Ser-Thr8-248 aa

PF19250DUF58989-48 aa

PF01636APH10-53 aa

PF15252DUF458914-56 aa

PF14531Kinase-like106-199 aa

PF01636APH118-148 aa

PF19250DUF5898240-257 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA04G401470	`PF00069`	Pkinase	5	252	2.5e-54	185.2
TkA04G401470	`PF07714`	PK_Tyr_Ser-Thr	8	248	2.8e-30	106.2
TkA04G401470	`PF19250`	DUF5898	9	48	0.27	11.9
TkA04G401470	`PF01636`	APH	10	53	0.0073	16.8
TkA04G401470	`PF15252`	DUF4589	14	56	0.11	13.2
TkA04G401470	`PF14531`	Kinase-like	106	199	0.00078	19.5
TkA04G401470	`PF01636`	APH	118	148	0.0073	16.8
TkA04G401470	`PF19250`	DUF5898	240	257	0.27	11.9
TkA04G401470	`PF23974`	DUF7300	321	345	0.12	13.0

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

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Protein	Organism	Description	Identity	Database	Confidence
`Q9ZVP5`	Arabidopsis thaliana	sp\|Q9ZVP5\|M3K18_ARATH Mitogen-activated protein kinase kinase kinase 18	51.500%	Swiss-Prot	High
`O80888`	Arabidopsis thaliana	sp\|O80888\|M3K17_ARATH Mitogen-activated protein kinase kinase kinase 17	51.700%	Swiss-Prot	High
`Q9SND6`	Arabidopsis thaliana	sp\|Q9SND6\|M3K20_ARATH Mitogen-activated protein kinase kinase kinase 20	37.900%	Swiss-Prot	Medium
`Q9FZ36`	Arabidopsis thaliana	sp\|Q9FZ36\|M3K2_ARATH Mitogen-activated protein kinase kinase kinase 2	36.300%	Swiss-Prot	Medium

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