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基因详情

输入 TK1151 或 OH-1004 基因 ID，查看对应参考版本的序列、功能注释与分析结果。
上下游长度，最大 10000 bp
示例 TkA01G624900 LXL04_000258

基因概览

TkA01G440800
当前版本: TK1151 染色体: Chr01 坐标: 110127654-110128721 链方向: - 类型: protein_coding

cDNA / CDS / 蛋白序列

可用序列下载 CDS FASTA 蛋白 FASTA cDNA FASTA

cDNA

下载 cDNA FASTA

1035 bp · TkA01G440800|TK1151|cDNA

ATGAAGCCCATTCTACCTCCGCCGCCCACCGCATCTGCTAATCGTCCACGACGTCGTCCTGACCTAACCCTACCCTTGCCCCAACGTCAACCCCAAATCGCCGTCCCCCTCCCTCTCCCACCCACTTCAGCCCCTAGACAGCAACCCTTCAACATATCGGAACTCGACCGTATGAACAGAATCGGCAGCGGTAGCGGCGGAACCGTCTATAAAGTACTCCACCGCCCTACCGGCCGACCGTTCGCCCTCAAAGTAATCTA...

CDS

下载 CDS FASTA

1035 bp · TkA01G440800|TK1151|CDS

ATGAAGCCCATTCTACCTCCGCCGCCCACCGCATCTGCTAATCGTCCACGACGTCGTCCTGACCTAACCCTACCCTTGCCCCAACGTCAACCCCAAATCGCCGTCCCCCTCCCTCTCCCACCCACTTCAGCCCCTAGACAGCAACCCTTCAACATATCGGAACTCGACCGTATGAACAGAATCGGCAGCGGTAGCGGCGGAACCGTCTATAAAGTACTCCACCGCCCTACCGGCCGACCGTTCGCCCTCAAAGTAATCTA...

蛋白

下载 蛋白 FASTA

344 aa · TkA01G440800|TK1151|PROTEIN

MKPILPPPPTASANRPRRRPDLTLPLPQRQPQIAVPLPLPPTSAPRQQPFNISELDRMNRIGSGSGGTVYKVLHRPTGRPFALKVIYGNHEDDVRRQICREIEILRDVDNLNIVKCHDMFDHGGEIQVLLEYMDGGSLEGTHISHEASLADLTRQVLSGIYYLHRRKIVHRDIKPSNLLINSKKQVKIADFGVSRILAQTMDPCNSSVGTIAYMSPERINTDLNHGKYDGFAGDIWSLGVSILEFYLGRFPFAVGRQGDW...

上下游序列下载

序列方向与下载说明

上游/下游最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

仅下载基因 CDS 下载蛋白序列

多版本 ID 对照

输入 IDTkA01G440800
TK1151 IDTkA01G440800
OH-1004 IDLXL04_002232
关系 / 置信度跨参考版本对应关系 / 复杂对应关系
蛋白一致性 (%)96.400
蛋白覆盖度 (%)TK1151 94.186 / OH-1004 92.798
覆盖度与证据说明

覆盖度为最高分比对片段的序列跨度占代表蛋白长度的比例。同源匹配不等同于功能验证。

版本TK1151 / GWHBCHF00000000
查看完整 ID 对照表
SNP / Indel 变异与样本携带情况CRA009020 · TK1151

展开后加载该基因的变异记录。

基因基本信息与功能注释

基因 IDTkA01G440800
位置Chr01:110127654-110128721 (-)
描述Similar to MKK5: Mitogen-activated protein kinase kinase 5
拟南芥 / 水稻参考基因与文献

下载当前基因文献

拟南芥

参考基因 ID可能功能对应论文 / DOI
At3g21220 丝裂原激活蛋白激酶激酶 ，可调节参与根生长和气孔反应的 MAPKKK20-MKK5-MPK6 级联中的脱落酸 反应，可能是通过蛋白质磷酸化激活 MAPK6 来实现的。
Cell death mediated by MAPK is associated with hydrogen peroxide production in Arabidopsis.2002 · DOI: 10.1074/jbc.m109495200
MAP kinase signalling cascade in Arabidopsis innate immunity.2002 · DOI: 10.1038/415977a
Stomatal development and patterning are regulated by environmentally responsive mitogen-activated protein kinases in Arabidopsis.2007 · DOI: 10.1105/tpc.106.048298
Ethylene signaling is required for the acceleration of cell death induced by the activation of AtMEK5 in Arabidopsis.2008 · DOI: 10.1038/cr.2008.29
Regulation of floral organ abscission in Arabidopsis thaliana.2008 · DOI: 10.1073/pnas.0805539105
A Pseudomonas syringae ADP-ribosyltransferase inhibits Arabidopsis mitogen-activated protein kinase kinases.2010 · DOI: 10.1105/tpc.110.075697
A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation.2012 · DOI: 10.1105/tpc.112.104695
Brassinosteroid-regulated GSK3/Shaggy-like kinases phosphorylate mitogen-activated protein (MAP) kinase kinases, which control stomata development in Arabidopsis thaliana.2013 · DOI: 10.1074/jbc.m112.384453
MKK5 regulates high light-induced gene expression of Cu/Zn superoxide dismutase 1 and 2 in Arabidopsis.2013 · DOI: 10.1093/pcp/pct072
Identification of BZR1-interacting proteins as potential components of the brassinosteroid signaling pathway in Arabidopsis through tandem affinity purification.2013 · DOI: 10.1074/mcp.m113.029256
AIK1, A Mitogen-Activated Protein Kinase, Modulates Abscisic Acid Responses through the MKK5-MPK6 Kinase Cascade.2017 · DOI: 10.1104/pp.16.01386
At1g51660 参与高敏感反应样细胞死亡期间过氧化氢生成的第二阶段。
MAP kinase signalling cascade in Arabidopsis innate immunity.2002 · DOI: 10.1038/415977a
Stomatal development and patterning are regulated by environmentally responsive mitogen-activated protein kinases in Arabidopsis.2007 · DOI: 10.1105/tpc.106.048298
Regulation of floral organ abscission in Arabidopsis thaliana.2008 · DOI: 10.1073/pnas.0805539105
Arabidopsis MKK4 mediates osmotic-stress response via its regulation of MPK3 activity.2011 · DOI: 10.1016/j.bbrc.2011.07.064
A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation.2012 · DOI: 10.1105/tpc.112.104695
Brassinosteroid-regulated GSK3/Shaggy-like kinases phosphorylate mitogen-activated protein (MAP) kinase kinases, which control stomata development in Arabidopsis thaliana.2013 · DOI: 10.1074/jbc.m112.384453
At1g73500 MKK9-MPK3/MPK6 模块磷酸化并激活 EIN3，从而促进乙烯信号传导中 EIN3 介导的转录。
Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling.2008 · DOI: 10.1038/nature06543
Activation of MAPK kinase 9 induces ethylene and camalexin biosynthesis and enhances sensitivity to salt stress in Arabidopsis.2008 · DOI: 10.1074/jbc.m801392200
An arabidopsis mitogen-activated protein kinase cascade, MKK9-MPK6, plays a role in leaf senescence.2009 · DOI: 10.1104/pp.108.133439
At1g18350 可能充当极性生长素运输的负调节剂。
Increased expression of MAP KINASE KINASE7 causes deficiency in polar auxin transport and leads to plant architectural abnormality in Arabidopsis.2006 · DOI: 10.1105/tpc.105.037846
Overexpression of Arabidopsis MAP kinase kinase 7 leads to activation of plant basal and systemic acquired resistance.2007 · DOI: 10.1111/j.1365-313x.2007.03294.x
At3g06230 促丝裂原活化蛋白激酶激酶8。 暂无已核实直接文献

水稻

当前来源表未检出该物种的同源命中。

功能注释来源
查看注释来源

功能注释来源：OH1004 · LXL04_002232 · GCA_047496595.1_OSU_TarKok_2.0。此处为经 ID 对照查得的 OH1004 注释；下方拟南芥/水稻同源表使用当前查询参考的独立蛋白比对。

GO 注释（OH1004 来源）
GO:0000165 MAPK cascade 生物过程
GO:0002229 defense response to oomycetes 生物过程
GO:0007165 signal transduction 生物过程
GO:0009611 response to wounding 生物过程
GO:0009620 response to fungus 生物过程
GO:0009626 plant-type hypersensitive response 生物过程
GO:0009651 response to salt stress 生物过程
GO:0009693 ethylene biosynthetic process 生物过程
GO:0009738 abscisic acid-activated signaling pathway 生物过程
GO:0009862 systemic acquired resistance, salicylic acid mediated signaling pathway 生物过程
GO:0009873 ethylene-activated signaling pathway 生物过程
GO:0009875 pollen-pistil interaction 生物过程
KEGG 基因交叉引用
ath:AT1G18350
ath:AT1G51660
ath:AT1G73500
ath:AT3G06230
ath:AT3G21220
以下为同源蛋白关联的 KEGG 基因编号，不代表本基因已获得通路功能验证。
打开注释模块

基因表达

查看该基因在不同研究、组织与处理条件下的表达量。表达结果按研究与计量单位分别展示。

查看该基因的表达量
数据来源与对应关系说明

表达数据来自公开转录组研究；参考版本、样本信息和表达单位见查询结果。跨参考版本的对应关系不唯一时，不自动选择表达记录；缺失值不视为表达量为零。

亚细胞定位 Top 5

以下为计算预测或同源注释，不能替代定位实验。

细胞核0.575
排名 1 · TkA01G440800 · TK1151
细胞质0.549
排名 2 · TkA01G440800 · TK1151
细胞膜0.088
排名 3 · TkA01G440800 · TK1151
内质网0.043
排名 4 · TkA01G440800 · TK1151
溶酶体／液泡0.036
排名 5 · TkA01G440800 · TK1151

LocPro · 直接预测 · 计算预测，非定位实验结果

进入亚细胞定位查询

预测功能结构域

结构域结果来自 Pfam-A/HMMER；位置为对应蛋白序列上的氨基酸坐标。

PF13095FTA236-95 aa
PF00069Pkinase57-310 aa
PF14531Kinase-like57-90 aa
PF07714PK_Tyr_Ser-Thr58-306 aa
PF01636APH60-148 aa
PF03109ABC161-108 aa
PF17667Pkinase_fungal66-115 aa
PF01163RIO189-192 aa
基因 ID结构域编号结构域名称起始 aa终止 aaE 值评分
TkA01G440800PF13095FTA236950.003317.8
TkA01G440800PF00069Pkinase573103.5e-65220.7
TkA01G440800PF14531Kinase-like57903.4e-0627.2
TkA01G440800PF07714PK_Tyr_Ser-Thr583065.2e-36125.0
TkA01G440800PF01636APH601480.004517.5
TkA01G440800PF03109ABC1611082.4e-0627.6
TkA01G440800PF17667Pkinase_fungal661150.0009518.7
TkA01G440800PF01163RIO1891920.1912.1
TkA01G440800PF12330Haspin_kinase1171970.01914.8
TkA01G440800PF03109ABC11291982.4e-0627.6
TkA01G440800PF14531Kinase-like1462533.4e-0627.2
TkA01G440800PF13095FTA21531810.003317.8
TkA01G440800PF17667Pkinase_fungal1542210.0009518.7
TkA01G440800PF01636APH1631860.004517.5

拟南芥 / 水稻蛋白同源

仅展示拟南芥和水稻；Swiss-Prot 为人工审校条目，TrEMBL 为补充序列候选。同源相似性不等同于实验验证。

下载当前结果

蛋白物种描述一致性数据库置信等级
Q8RXG3拟南芥sp|Q8RXG3|M2K5_ARATH Mitogen-activated protein kinase kinase 575.100%Swiss-Prot高置信
O80397拟南芥sp|O80397|M2K4_ARATH Mitogen-activated protein kinase kinase 467.800%Swiss-Prot高置信
Q9FX43拟南芥sp|Q9FX43|M2K9_ARATH Mitogen-activated protein kinase kinase 952.100%Swiss-Prot高置信
Q9LPQ3拟南芥sp|Q9LPQ3|M2K7_ARATH Mitogen-activated protein kinase kinase 750.000%Swiss-Prot高置信
Q9M8J5拟南芥sp|Q9M8J5|M2K8_ARATH Mitogen-activated protein kinase kinase 847.000%Swiss-Prot中等置信

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