TkA01G371910 | RubberDandelionOmics

Gene overview

TkA01G371910

Reference: TK1151 Chr: Chr01 Coordinates: 92742622-92744691 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

711 bp · TkA01G371910|TK1151|cDNA

ATGCGTTGTCCGTGTGTGATATGTGTGAATAGGTTGTTTGAAACACCGGTTACGGAGGTGGCAGTGAAGAAGTTTCTTGATCAGGATTTTTCAGGTGCTGCATTAGCAGAGTTCAAGAGAGAAGTGAGGATTATGCAGAGATTAAGGCATCCAAATGTAGTGCTATTTATGGGAGCTGTTACTCGCCCTCCAACTCTTTCAATCATCACAGAGTTTCTCCCCAGAGGAAGTTTATACAGGATAATTCATCGTCCACATTG...

CDS

Download CDS FASTA

711 bp · TkA01G371910|TK1151|CDS

ATGCGTTGTCCGTGTGTGATATGTGTGAATAGGTTGTTTGAAACACCGGTTACGGAGGTGGCAGTGAAGAAGTTTCTTGATCAGGATTTTTCAGGTGCTGCATTAGCAGAGTTCAAGAGAGAAGTGAGGATTATGCAGAGATTAAGGCATCCAAATGTAGTGCTATTTATGGGAGCTGTTACTCGCCCTCCAACTCTTTCAATCATCACAGAGTTTCTCCCCAGAGGAAGTTTATACAGGATAATTCATCGTCCACATTG...

Protein

Download Protein FASTA

236 aa · TkA01G371910|TK1151|PROTEIN

MRCPCVICVNRLFETPVTEVAVKKFLDQDFSGAALAEFKREVRIMQRLRHPNVVLFMGAVTRPPTLSIITEFLPRGSLYRIIHRPHCQIDEKQRIKIALDVAKGMNCLHTSIPTIVHRDLKSPNLLVDEDWNVKVCDFGLSCLKHNTFLSSKSTAGTPEWMAPEVLRNENSNENDSMRNEGLNIFLHLLRDSISNRASCVRVGTLGFLRDWFPCEDKDWLRGLICANGGCNLPGGI

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA01G371910`
TK1151 ID	TkA01G371910
OH-1004 ID	LXL04_010569
Relationship / confidence	Rbh Below Probable Coverage Or Synteny Threshold / Review
Protein identity (%)	89.600
Protein coverage (%)	TK1151 99.576 / OH-1004 82.278 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

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SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene ID TkA01G371910

Location Chr01:92742622-92744691 (-)

Description Similar to EDR1: Serine/threonine-protein kinase EDR1

Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At1g08720`	MAPKKK serine/threonine-protein kinase involved in the regulation of a MAP kinase cascade (probably including MPK3 and MPK6) that negatively regulates salicylic acid- (SA-) dependent defense responses, abscisic acid (ABA) signaling, and ethylene-induced senescence.	Negative regulation of defense responses in plants by a conserved MAPKK kinase.2001 · DOI: 10.1073/pnas.98.1.373 Overexpression of a kinase-deficient form of the EDR1 gene enhances powdery mildew resistance and ethylene-induced senescence in Arabidopsis.2002 · DOI: 10.1046/j.1365-313x.2002.01482.x Regulation of plant disease resistance, stress responses, cell death, and ethylene signaling in Arabidopsis by the EDR1 protein kinase.2005 · DOI: 10.1104/pp.105.060400 Costs and benefits of priming for defense in Arabidopsis.2006 · DOI: 10.1073/pnas.0510213103 Powdery mildew resistance conferred by loss of the ENHANCED DISEASE RESISTANCE1 protein kinase is suppressed by a missense mutation in KEEP ON GOING, a regulator of abscisic acid signaling.2008 · DOI: 10.1104/pp.108.127605 Mitogen-activated protein kinases 3 and 6 are required for full priming of stress responses in Arabidopsis thaliana.2009 · DOI: 10.1105/tpc.108.062158 The KEEP ON GOING protein of Arabidopsis recruits the ENHANCED DISEASE RESISTANCE1 protein to trans-Golgi network/early endosome vesicles.2011 · DOI: 10.1104/pp.110.171785 Arabidopsis ENHANCED DISEASE RESISTANCE 1 is required for pathogen-induced expression of plant defensins in nonhost resistance, and acts through interference of MYC2-mediated repressor function.2011 · DOI: 10.1111/j.1365-313x.2011.04651.x Negative regulation of defence signalling pathways by the EDR1 protein kinase.2011 · DOI: 10.1111/j.1364-3703.2011.00708.x An Arabidopsis mutant with enhanced resistance to powdery mildew.1998 · DOI: 10.1105/tpc.10.6.947
`At1g73660`	Acts as a negative regulator of salt tolerance.	The genetic locus At1g73660 encodes a putative MAPKKK and negatively regulates salt tolerance in Arabidopsis.2008 · DOI: 10.1007/s11103-008-9306-8 SIS8, a putative mitogen-activated protein kinase kinase kinase, regulates sugar-resistant seedling development in Arabidopsis.2014 · DOI: 10.1111/tpj.12404
`At5g03730`	Acts as a negative regulator in the ethylene response pathway.	CTR1 phosphorylates the central regulator EIN2 to control ethylene hormone signaling from the ER membrane to the nucleus in Arabidopsis.2012 · DOI: 10.1073/pnas.1214848109 Unsaturation of very-long-chain ceramides protects plant from hypoxia-induced damages by modulating ethylene signaling in Arabidopsis.2015 · DOI: 10.1371/journal.pgen.1005143 CTR1, a negative regulator of the ethylene response pathway in Arabidopsis, encodes a member of the raf family of protein kinases.1993 · DOI: 10.1016/0092-8674(93)90119-b

Rice

No hit for this species in the current source table.

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_010569 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0000165 MAPK cascade Biological Process

GO:0001666 response to hypoxia Biological Process

GO:0002229 defense response to oomycetes Biological Process

GO:0007165 signal transduction Biological Process

GO:0009414 response to water deprivation Biological Process

GO:0009617 response to bacterium Biological Process

GO:0009620 response to fungus Biological Process

GO:0009651 response to salt stress Biological Process

GO:0009686 gibberellin biosynthetic process Biological Process

GO:0009723 response to ethylene Biological Process

GO:0009738 abscisic acid-activated signaling pathway Biological Process

GO:0009744 response to sucrose Biological Process

KEGG gene cross-reference

ath:AT1G08720

ath:AT1G73660

ath:AT5G03730

ddi:DDB_G0281557

ddi:DDB_G0289791

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

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Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Cytoplasm0.476

Rank 1 · TkA01G371910 · TK1151

Nucleus0.258

Rank 2 · TkA01G371910 · TK1151

Cell membrane0.211

Rank 3 · TkA01G371910 · TK1151

Mitochondrion0.111

Rank 4 · TkA01G371910 · TK1151

Endoplasmic reticulum0.109

Rank 5 · TkA01G371910 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF07714PK_Tyr_Ser-Thr17-172 aa

PF00069Pkinase18-171 aa

PF01636APH30-50 aa

PF17667Pkinase_fungal100-170 aa

PF03109ABC1112-142 aa

PF01636APH113-143 aa

PF12330Haspin_kinase117-146 aa

PF20425Neurobeachin174-219 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA01G371910	`PF07714`	PK_Tyr_Ser-Thr	17	172	5.3e-35	121.7
TkA01G371910	`PF00069`	Pkinase	18	171	2.8e-34	119.4
TkA01G371910	`PF01636`	APH	30	50	0.0016	19.0
TkA01G371910	`PF17667`	Pkinase_fungal	100	170	0.19	11.1
TkA01G371910	`PF03109`	ABC1	112	142	0.34	10.7
TkA01G371910	`PF01636`	APH	113	143	0.0016	19.0
TkA01G371910	`PF12330`	Haspin_kinase	117	146	0.024	14.4
TkA01G371910	`PF20425`	Neurobeachin	174	219	2.3e-15	57.2

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

Protein	Organism	Description	Identity	Database	Confidence
`Q9FPR3`	Arabidopsis thaliana	sp\|Q9FPR3\|EDR1_ARATH Serine/threonine-protein kinase EDR1	74.300%	Swiss-Prot	High
`Q9C9U5`	Arabidopsis thaliana	sp\|Q9C9U5\|SIS8_ARATH Probable serine/threonine-protein kinase SIS8	65.400%	Swiss-Prot	High
`Q05609`	Arabidopsis thaliana	sp\|Q05609\|CTR1_ARATH Serine/threonine-protein kinase CTR1	59.100%	Swiss-Prot	High

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