LXL04_002260 | RubberDandelionOmics

Gene overview

LXL04_002260

Reference: OH-1004 Chr: Chr01 Coordinates: 44772001-44777948 Strand: + Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

3162 bp · LXL04_002260|LXL04_002260|OH1004|cDNA

ATGCACGGCAATGGAGTTATCGGAATTCTCTCAGAGTCTACAAACAAGTGGGAACGAAGGGTTCCTTTAACGCCATCACACTGTGCTCGACTTTTGCACAGTGGCAAGGGTAAAGTGGAAGTGTCGCGCATTATTGTACAGCCATCAACAAAGCGAATTCATCATGATGCTCTTTATGAGGATGTTGGCTGTGAGATTTCTGAGGATTTATCTGATTGTGGTCTCATATTGGGAATCAAGCAACCAAAGTTGGAGATGAT...

CDS

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3162 bp · LXL04_002260|LXL04_002260|OH1004|CDS

ATGCACGGCAATGGAGTTATCGGAATTCTCTCAGAGTCTACAAACAAGTGGGAACGAAGGGTTCCTTTAACGCCATCACACTGTGCTCGACTTTTGCACAGTGGCAAGGGTAAAGTGGAAGTGTCGCGCATTATTGTACAGCCATCAACAAAGCGAATTCATCATGATGCTCTTTATGAGGATGTTGGCTGTGAGATTTCTGAGGATTTATCTGATTGTGGTCTCATATTGGGAATCAAGCAACCAAAGTTGGAGATGAT...

Protein

Download Protein FASTA

1053 aa · LXL04_002260|LXL04_002260|OH1004|PROTEIN

MHGNGVIGILSESTNKWERRVPLTPSHCARLLHSGKGKVEVSRIIVQPSTKRIHHDALYEDVGCEISEDLSDCGLILGIKQPKLEMILPDRAYAFFSHTHKAQIENMPLLDKILAEKASLFDYELIAGDKGKRLLAFGKFAGRAGLIDFLSGLGRRYLSLGYSTPFLSLGSSYMYPSLAAAKAAVVSVGEEIATTGLPSSISPLVFVFTGSGNVSLGAQEIFKLLPHTFVDPSKLPRLFDKGVDLCQPKRAFQVYGCVVT...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`LXL04_002260`
Source version	OH-1004 / GCA_047496595.1_OSU_TarKok_2.0

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SNP / Indel variants and carrier samplesCRA009020 · OH-1004

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Basic Information and Functional Annotation

Gene ID LXL04_002260

Location Chr01:44772001-44777948 (+)

Description Similar to LKR/SDH: Alpha-aminoadipic semialdehyde synthase

Arabidopsis / Rice Reference Genes and Papers

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Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At4g33150`	Bifunctional enzyme that catalyzes the first two steps in lysine degradation.	A T-DNA insertion knockout of the bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase gene elevates lysine levels in Arabidopsis seeds.2001 · DOI: 10.1104/pp.126.4.1539

Rice

No hit for this species in the current source table.

Functional annotation source

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Functional annotation source: OH1004 · LXL04_002260 · GCA_047496595.1_OSU_TarKok_2.0.

GO annotations (OH1004 source)

GO:0006091 generation of precursor metabolites and energy Biological Process

GO:0006554 lysine catabolic process Biological Process

GO:0019477 L-lysine catabolic process Biological Process

GO:0019878 L-lysine biosynthetic process via aminoadipic acid Biological Process

GO:0033512 L-lysine catabolic process to acetyl-CoA via L-saccharopine Biological Process

GO:0005737 cytoplasm Cellular Component

GO:0005739 mitochondrion Cellular Component

GO:0005829 cytosol Cellular Component

GO:0004753 saccharopine dehydrogenase activity Molecular Function

GO:0047130 saccharopine dehydrogenase (NADP+, L-lysine-forming) activity Molecular Function

GO:0047131 saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity Molecular Function

KEGG gene cross-reference

ath:AT4G33150

bta:520865

mmu:30956

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

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Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

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Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Cytoplasm0.691

Rank 1 · LXL04_002260 · OH-1004

Nucleus0.282

Rank 2 · LXL04_002260 · OH-1004

Mitochondrion0.111

Rank 3 · LXL04_002260 · OH-1004

Peroxisome0.080

Rank 4 · LXL04_002260 · OH-1004

Cell membrane0.050

Rank 5 · LXL04_002260 · OH-1004

LocPro · Direct prediction · Computational prediction, not experimental localization

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Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF05222.22AlaDh_PNT_N8-143 aa

PF04455.18Saccharop_dh_N464-531 aa

PF03435.25Sacchrp_dh_NADP574-708 aa

PF16653.11Sacchrp_dh_C713-1045 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
LXL04_002260	`PF05222.22`	AlaDh_PNT_N	8	143	5.1e-20	72.8
LXL04_002260	`PF04455.18`	Saccharop_dh_N	464	531	1.4e-19	71.1
LXL04_002260	`PF03435.25`	Sacchrp_dh_NADP	574	708	1.3e-17	65.0
LXL04_002260	`PF16653.11`	Sacchrp_dh_C	713	1045	1.4e-79	268.5

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

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Protein	Organism	Description	Identity	Database	Confidence
`Q9SMZ4`	Arabidopsis thaliana	Alpha-aminoadipic semialdehyde synthase	66.383%	Swiss-Prot	strong database homology

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