基因注释

展示当前基因的功能描述、GO/KEGG 注释及分物种同源证据。命中结果按查询版本、序列来源和比对证据分层显示。

示例 TkA01G624900 LXL04_000258 文献示例 LXL04_039733 TkAUNG001940

查询结果

基因 ID	`LXL04_003014`
当前查询版本	OH1004
位置	Chr01:64987114-64995744 (+)
描述	Similar to PAD4: Lipase-like PAD4 (Arabidopsis thaliana OX%3D3702)
注释来源组装	GCA_047496595.1_OSU_TarKok_2.0

功能注释来源：OH1004 · LXL04_003014 · GCA_047496595.1_OSU_TarKok_2.0。

当前查询返回来自 OH1004 注释条目的 39 条 GO 注释和 3 条 KEGG 基因交叉引用；只下载当前查询结果，不据此推断 KEGG 通路成员。

拟南芥 / 水稻参考基因与文献

文献对应拟南芥或水稻参考基因；橡胶草的功能关联来自当前参考组装的蛋白序列比对。

下载当前基因文献

拟南芥

参考基因 ID	可能功能	对应论文 / DOI
`At3g52430`	可能需要 MPK4 下游的脂肪酶来积累植物防御增强分子水杨酸，从而有助于植物针对侵入性生物营养病原体的先天免疫，并有助于识别微生物相关分子模式后的防御机制。	Arabidopsis thaliana PAD4 encodes a lipase-like gene that is important for salicylic acid signaling.1999 · DOI: 10.1073/pnas.96.23.13583 Arabidopsis thaliana EDS4 contributes to salicylic acid (SA)-dependent expression of defense responses: evidence for inhibition of jasmonic acid signaling by SA.2000 · DOI: 10.1094/mpmi.2000.13.5.503 Fumonisin B1-induced cell death in arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways.2000 · DOI: 10.1105/tpc.12.10.1823 Direct interaction between the Arabidopsis disease resistance signaling proteins, EDS1 and PAD4.2001 · DOI: 10.1093/emboj/20.19.5400 The disease resistance signaling components EDS1 and PAD4 are essential regulators of the cell death pathway controlled by LSD1 in Arabidopsis.2001 · DOI: 10.1105/tpc.010085 EDS5, an essential component of salicylic acid-dependent signaling for disease resistance in Arabidopsis, is a member of the MATE transporter family.2002 · DOI: 10.1105/tpc.010376 Arabidopsis RPP4 is a member of the RPP5 multigene family of TIR-NB-LRR genes and confers downy mildew resistance through multiple signalling components.2002 · DOI: 10.1046/j.0960-7412.2001.01229.x Genetic evidence that expression of NahG modifies defence pathways independent of salicylic acid biosynthesis in the Arabidopsis-Pseudomonas syringae pv. tomato interaction.2003 · DOI: 10.1046/j.1365-313x.2003.01881.x LESION SIMULATING DISEASE 1 is required for acclimation to conditions that promote excess excitation energy.2004 · DOI: 10.1104/pp.104.043646 A key role for ALD1 in activation of local and systemic defenses in Arabidopsis.2004 · DOI: 10.1111/j.1365-313x.2004.02200.x The atypical resistance gene, RPW8, recruits components of basal defence for powdery mildew resistance in Arabidopsis.2005 · DOI: 10.1111/j.1365-313x.2005.02356.x Arabidopsis SENESCENCE-ASSOCIATED GENE101 stabilizes and signals within an ENHANCED DISEASE SUSCEPTIBILITY1 complex in plant innate immunity.2005 · DOI: 10.1105/tpc.105.033910 Premature leaf senescence modulated by the Arabidopsis PHYTOALEXIN DEFICIENT4 gene is associated with defense against the phloem-feeding green peach aphid.2005 · DOI: 10.1104/pp.105.070433 Genetic analysis of developmentally regulated resistance to downy mildew (Hyaloperonospora parasitica) in Arabidopsis thaliana.2005 · DOI: 10.1094/mpmi-18-1226 Arabidopsis MAP kinase 4 regulates salicylic acid- and jasmonic acid/ethylene-dependent responses via EDS1 and PAD4.2006 · DOI: 10.1111/j.1365-313x.2006.02806.x Plastidial fatty acid levels regulate resistance gene-dependent defense signaling in Arabidopsis.2007 · DOI: 10.1073/pnas.0609259104 Phloem-based resistance to green peach aphid is controlled by Arabidopsis PHYTOALEXIN DEFICIENT4 without its signaling partner ENHANCED DISEASE SUSCEPTIBILITY1.2007 · DOI: 10.1111/j.1365-313x.2007.03241.x Lysigenous aerenchyma formation in Arabidopsis is controlled by LESION SIMULATING DISEASE1.2007 · DOI: 10.1105/tpc.106.048843 Arabidopsis proteins important for modulating defense responses to Pseudomonas syringae that secrete HopW1-1.2008 · DOI: 10.1111/j.1365-313x.2008.03439.x PAD4-dependent antibiosis contributes to the ssi2-conferred hyper-resistance to the green peach aphid.2010 · DOI: 10.1094/mpmi-23-5-0618 Different roles of Enhanced Disease Susceptibility1 (EDS1) bound to and dissociated from Phytoalexin Deficient4 (PAD4) in Arabidopsis immunity.2011 · DOI: 10.1111/j.1469-8137.2011.03675.x SAG101 forms a ternary complex with EDS1 and PAD4 and is required for resistance signaling against turnip crinkle virus.2011 · DOI: 10.1371/journal.ppat.1002318 Discrimination of Arabidopsis PAD4 activities in defense against green peach aphid and pathogens.2012 · DOI: 10.1104/pp.112.193417 Natural variation in small molecule-induced TIR-NB-LRR signaling induces root growth arrest via EDS1- and PAD4-complexed R protein VICTR in Arabidopsis.2012 · DOI: 10.1105/tpc.112.107235 Lesion simulating disease1, enhanced disease susceptibility1, and phytoalexin deficient4 conditionally regulate cellular signaling homeostasis, photosynthesis, water use efficiency, and seed yield in Arabidopsis.2013 · DOI: 10.1104/pp.112.208116 Isolation of Arabidopsis mutants with enhanced disease susceptibility by direct screening.1996 · DOI: 10.1093/genetics/143.2.973 Phytoalexin-deficient mutants of Arabidopsis reveal that PAD4 encodes a regulatory factor and that four PAD genes contribute to downy mildew resistance.1997 · DOI: 10.1093/genetics/146.1.381 PAD4 functions upstream from salicylic acid to control defense responses in Arabidopsis.1998 · DOI: 10.1105/tpc.10.6.1021 Correlation of defense gene induction defects with powdery mildew susceptibility in Arabidopsis enhanced disease susceptibility mutants.1998 · DOI: 10.1046/j.1365-313x.1998.00319.x
`At3g48080`	作为 EDS1 的第二个功能性拷贝。	暂无已核实直接文献
`UniProt: Q9XF23`	TIR-NB-LRR抗性蛋白特异介导的基础抗性和效应器触发免疫的正调控因子。	暂无已核实直接文献
`At3g48090`	是由 TIR-NB-LRR (TNL) 抗性蛋白特异介导的基础抗性和效应触发免疫的正调节因子。	EDS1, an essential component of R gene-mediated disease resistance in Arabidopsis has homology to eukaryotic lipases.1999 · DOI: 10.1073/pnas.96.6.3292 Direct interaction between the Arabidopsis disease resistance signaling proteins, EDS1 and PAD4.2001 · DOI: 10.1093/emboj/20.19.5400 Arabidopsis SENESCENCE-ASSOCIATED GENE101 stabilizes and signals within an ENHANCED DISEASE SUSCEPTIBILITY1 complex in plant innate immunity.2005 · DOI: 10.1105/tpc.105.033910 Balanced nuclear and cytoplasmic activities of EDS1 are required for a complete plant innate immune response.2010 · DOI: 10.1371/journal.ppat.1000970 Different roles of Enhanced Disease Susceptibility1 (EDS1) bound to and dissociated from Phytoalexin Deficient4 (PAD4) in Arabidopsis immunity.2011 · DOI: 10.1111/j.1469-8137.2011.03675.x Pathogen effectors target Arabidopsis EDS1 and alter its interactions with immune regulators.2011 · DOI: 10.1126/science.1211592 EDS1 contributes to nonhost resistance of Arabidopsis thaliana against Erwinia amylovora.2012 · DOI: 10.1094/mpmi-05-11-0111 Contrasting Roles of the Apoplastic Aspartyl Protease APOPLASTIC, ENHANCED DISEASE SUSCEPTIBILITY1-DEPENDENT1 and LEGUME LECTIN-LIKE PROTEIN1 in Arabidopsis Systemic Acquired Resistance.2014 · DOI: 10.1104/pp.114.239665
`At5g14930`	酰基水解酶触发叶片衰老。	Different roles of Enhanced Disease Susceptibility1 (EDS1) bound to and dissociated from Phytoalexin Deficient4 (PAD4) in Arabidopsis immunity.2011 · DOI: 10.1111/j.1469-8137.2011.03675.x SAG101 forms a ternary complex with EDS1 and PAD4 and is required for resistance signaling against turnip crinkle virus.2011 · DOI: 10.1371/journal.ppat.1002318

水稻

当前来源表未检出该物种的同源命中。

GO / KEGG

以下 GO/KEGG 注释源自上述 OH1004 注释条目，保留原始同源转移证据及覆盖度；其来源物种范围与拟南芥/水稻直接比对表不同。

类型	ID	名称	命名空间	证据	来源
GO	GO:0000304	response to singlet oxygen	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=5; 一致性=27.439; 覆盖度=49.398; E 值=6.81e-39; UniProt GO evidence=IGI:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0001666	response to hypoxia	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0002213	defense response to insect	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0006629	lipid metabolic process	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=3; 一致性=26.199; 覆盖度=58.635; E 值=4.53e-42; UniProt GO evidence=IEA:InterPro	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0006952	defense response	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=4; 一致性=26.978; 覆盖度=49.498; E 值=3.41e-39; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0009617	response to bacterium	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IDA:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0009625	response to insect	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IDA:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0009626	plant-type hypersensitive response	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0009627	systemic acquired resistance	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IEP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0009751	response to salicylic acid	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IDA:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0009862	systemic acquired resistance, salicylic acid mediated signaling pathway	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0009873	ethylene-activated signaling pathway	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0010105	negative regulation of ethylene-activated signaling pathway	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IGI:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0010150	leaf senescence	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0010225	response to UV-C	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0010310	regulation of hydrogen peroxide metabolic process	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0010618	aerenchyma formation	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0016042	lipid catabolic process	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0031348	negative regulation of defense response	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0042742	defense response to bacterium	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0050829	defense response to Gram-negative bacterium	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0051707	response to other organism	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IEP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0060866	leaf abscission	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0071327	cellular response to trehalose stimulus	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IDA:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0080142	regulation of salicylic acid biosynthetic process	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0080151	positive regulation of salicylic acid mediated signaling pathway	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IGI:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:1900367	positive regulation of defense response to insect	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:1900426	positive regulation of defense response to bacterium	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:1901183	positive regulation of camalexin biosynthetic process	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:2000022	regulation of jasmonic acid mediated signaling pathway	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IGI:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:2000031	regulation of salicylic acid mediated signaling pathway	生物过程	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0005634	nucleus	细胞组分	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IDA:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0005737	cytoplasm	细胞组分	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IDA:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0005829	cytosol	细胞组分	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IDA:ComplexPortal	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0009507	chloroplast	细胞组分	Swiss-Prot reviewed 同源转移; 命中排序=5; 一致性=27.439; 覆盖度=49.398; E 值=6.81e-39; UniProt GO evidence=IDA:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0016298	lipase activity	分子功能	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=ISS:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0016740	transferase activity	分子功能	Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0016787	hydrolase activity	分子功能	Swiss-Prot reviewed 同源转移; 命中排序=3; 一致性=26.199; 覆盖度=58.635; E 值=4.53e-42; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release
GO	GO:0042803	protein homodimerization activity	分子功能	Swiss-Prot reviewed 同源转移; 命中排序=5; 一致性=27.439; 覆盖度=49.398; E 值=6.81e-39; UniProt GO evidence=IDA:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release
KEGG	ath:AT3G48080	KEGG gene cross-reference from reviewed UniProt hit; pathway name pending		Swiss-Prot reviewed 同源转移; 命中排序=3; 一致性=26.199; 覆盖度=58.635; E 值=4.53e-42	UniProtKB/Swiss-Prot DAT 2026 current_release
KEGG	ath:AT3G48090	KEGG gene cross-reference from reviewed UniProt hit; pathway name pending		Swiss-Prot reviewed 同源转移; 命中排序=5; 一致性=27.439; 覆盖度=49.398; E 值=6.81e-39	UniProtKB/Swiss-Prot DAT 2026 current_release
KEGG	ath:AT3G52430	KEGG gene cross-reference from reviewed UniProt hit; pathway name pending		Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=42.416; 覆盖度=39.056; E 值=3.26e-84	UniProtKB/Swiss-Prot DAT 2026 current_release