LXL04_021464 | RubberDandelionOmics

基因概览

LXL04_021464

当前版本: OH-1004 染色体: Chr04 坐标: 130697153-130698103 链方向: + 类型: protein_coding

cDNA / CDS / 蛋白序列

可用序列下载 CDS FASTA 蛋白 FASTA cDNA FASTA

cDNA

951 bp · LXL04_021464|LXL04_021464|OH1004|cDNA

ATGGCCCTCGTTCGTGAACGACGTCAGCCAAAACTCGGCCTCCGATTACCGGAGATCTCCGATCGCCGCCCTCGTTTCCCCCTACCCCTCCCCCCCACCACCCTTCAACAATCGGCAACCACCCCCTCatccaccaccgccgccgaACTGGAGACCCTTCAAGTCCTGGGTCACGGCAACGGCGGTACCGTCTACAAAGTAGTACATAAGAAAACGTCTAACGTTTACGCGCTCAAGGTTGTACATGCCGACAGTGATCC...

CDS

下载 CDS FASTA

951 bp · LXL04_021464|LXL04_021464|OH1004|CDS

ATGGCCCTCGTTCGTGAACGACGTCAGCCAAAACTCGGCCTCCGATTACCGGAGATCTCCGATCGCCGCCCTCGTTTCCCCCTACCCCTCCCCCCCACCACCCTTCAACAATCGGCAACCACCCCCTCATCCACCACCGCCGCCGAACTGGAGACCCTTCAAGTCCTGGGTCACGGCAACGGCGGTACCGTCTACAAAGTAGTACATAAGAAAACGTCTAACGTTTACGCGCTCAAGGTTGTACATGCCGACAGTGATCC...

蛋白

下载蛋白 FASTA

316 aa · LXL04_021464|LXL04_021464|OH1004|PROTEIN

MALVRERRQPKLGLRLPEISDRRPRFPLPLPPTTLQQSATTPSSTTAAELETLQVLGHGNGGTVYKVVHKKTSNVYALKVVHADSDPMMRRQIFREMEILRRTDSPFVVHCHEIFEKPDGDIAILMEYMDAGTLDSLLKTGGTFTEKSLADIARQILNGLNYLHAHKIIHRDIKPANLLVNKNMEVKIADFGVSKIMCRTLDACNSYVGTCAYMSPERFDPDTHGANYNGYSGDIWSLGLTMLELYMGHFPLLPAGQKPD...

上下游序列下载

序列方向与下载说明

上游/下游最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

多版本 ID 对照

输入 ID	`LXL04_021464`
TK1151 ID	TkA05G398130
OH-1004 ID	LXL04_021464
关系 / 置信度	跨参考版本对应关系 / Strict
蛋白一致性 (%)	100.000
蛋白覆盖度 (%)	TK1151 100.000 / OH-1004 100.000 覆盖度与证据说明覆盖度为最高分比对片段的序列跨度占代表蛋白长度的比例。同源匹配不等同于功能验证。
版本	OH-1004 / GCA_047496595.1_OSU_TarKok_2.0

查看完整 ID 对照表

SNP / Indel 变异与样本携带情况CRA009020 · OH-1004

展开后加载该基因的变异记录。

基因基本信息与功能注释

基因 ID LXL04_021464

位置 Chr04:130697153-130698103 (+)

描述 Similar to MKK9: Mitogen-activated protein kinase kinase 9

拟南芥 / 水稻参考基因与文献

下载当前基因文献

拟南芥

参考基因 ID	可能功能	对应论文 / DOI
`At1g73500`	MKK9-MPK3/MPK6 模块磷酸化并激活 EIN3，从而促进乙烯信号传导中 EIN3 介导的转录。	Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling.2008 · DOI: 10.1038/nature06543 Activation of MAPK kinase 9 induces ethylene and camalexin biosynthesis and enhances sensitivity to salt stress in Arabidopsis.2008 · DOI: 10.1074/jbc.m801392200 An arabidopsis mitogen-activated protein kinase cascade, MKK9-MPK6, plays a role in leaf senescence.2009 · DOI: 10.1104/pp.108.133439
`At1g18350`	可能充当极性生长素运输的负调节剂。	Increased expression of MAP KINASE KINASE7 causes deficiency in polar auxin transport and leads to plant architectural abnormality in Arabidopsis.2006 · DOI: 10.1105/tpc.105.037846 Overexpression of Arabidopsis MAP kinase kinase 7 leads to activation of plant basal and systemic acquired resistance.2007 · DOI: 10.1111/j.1365-313x.2007.03294.x
`At3g06230`	促丝裂原活化蛋白激酶激酶8。	暂无已核实直接文献
`At3g21220`	丝裂原激活蛋白激酶激酶，可调节参与根生长和气孔反应的 MAPKKK20-MKK5-MPK6 级联中的脱落酸反应，可能是通过蛋白质磷酸化激活 MAPK6 来实现的。	Cell death mediated by MAPK is associated with hydrogen peroxide production in Arabidopsis.2002 · DOI: 10.1074/jbc.m109495200 MAP kinase signalling cascade in Arabidopsis innate immunity.2002 · DOI: 10.1038/415977a Stomatal development and patterning are regulated by environmentally responsive mitogen-activated protein kinases in Arabidopsis.2007 · DOI: 10.1105/tpc.106.048298 Ethylene signaling is required for the acceleration of cell death induced by the activation of AtMEK5 in Arabidopsis.2008 · DOI: 10.1038/cr.2008.29 Regulation of floral organ abscission in Arabidopsis thaliana.2008 · DOI: 10.1073/pnas.0805539105 A Pseudomonas syringae ADP-ribosyltransferase inhibits Arabidopsis mitogen-activated protein kinase kinases.2010 · DOI: 10.1105/tpc.110.075697 A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation.2012 · DOI: 10.1105/tpc.112.104695 Brassinosteroid-regulated GSK3/Shaggy-like kinases phosphorylate mitogen-activated protein (MAP) kinase kinases, which control stomata development in Arabidopsis thaliana.2013 · DOI: 10.1074/jbc.m112.384453 MKK5 regulates high light-induced gene expression of Cu/Zn superoxide dismutase 1 and 2 in Arabidopsis.2013 · DOI: 10.1093/pcp/pct072 Identification of BZR1-interacting proteins as potential components of the brassinosteroid signaling pathway in Arabidopsis through tandem affinity purification.2013 · DOI: 10.1074/mcp.m113.029256 AIK1, A Mitogen-Activated Protein Kinase, Modulates Abscisic Acid Responses through the MKK5-MPK6 Kinase Cascade.2017 · DOI: 10.1104/pp.16.01386
`At1g51660`	参与高敏感反应样细胞死亡期间过氧化氢生成的第二阶段。	MAP kinase signalling cascade in Arabidopsis innate immunity.2002 · DOI: 10.1038/415977a Stomatal development and patterning are regulated by environmentally responsive mitogen-activated protein kinases in Arabidopsis.2007 · DOI: 10.1105/tpc.106.048298 Regulation of floral organ abscission in Arabidopsis thaliana.2008 · DOI: 10.1073/pnas.0805539105 Arabidopsis MKK4 mediates osmotic-stress response via its regulation of MPK3 activity.2011 · DOI: 10.1016/j.bbrc.2011.07.064 A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation.2012 · DOI: 10.1105/tpc.112.104695 Brassinosteroid-regulated GSK3/Shaggy-like kinases phosphorylate mitogen-activated protein (MAP) kinase kinases, which control stomata development in Arabidopsis thaliana.2013 · DOI: 10.1074/jbc.m112.384453

水稻

当前来源表未检出该物种的同源命中。

功能注释来源

查看注释来源

功能注释来源：OH1004 · LXL04_021464 · GCA_047496595.1_OSU_TarKok_2.0。

GO 注释（OH1004 来源）

GO:0000165 MAPK cascade 生物过程

GO:0002229 defense response to oomycetes 生物过程

GO:0007165 signal transduction 生物过程

GO:0009611 response to wounding 生物过程

GO:0009620 response to fungus 生物过程

GO:0009626 plant-type hypersensitive response 生物过程

GO:0009651 response to salt stress 生物过程

GO:0009693 ethylene biosynthetic process 生物过程

GO:0009738 abscisic acid-activated signaling pathway 生物过程

GO:0009862 systemic acquired resistance, salicylic acid mediated signaling pathway 生物过程

GO:0009873 ethylene-activated signaling pathway 生物过程

GO:0009875 pollen-pistil interaction 生物过程

KEGG 基因交叉引用

ath:AT1G18350

ath:AT1G51660

ath:AT1G73500

ath:AT3G06230

ath:AT3G21220

以下为同源蛋白关联的 KEGG 基因编号，不代表本基因已获得通路功能验证。

打开注释模块

基因表达

查看该基因在不同研究、组织与处理条件下的表达量。表达结果按研究与计量单位分别展示。

查看该基因的表达量

数据来源与对应关系说明

表达数据来自公开转录组研究；参考版本、样本信息和表达单位见查询结果。跨参考版本的对应关系不唯一时，不自动选择表达记录；缺失值不视为表达量为零。

亚细胞定位 Top 5

以下为计算预测或同源注释，不能替代定位实验。

细胞质0.599

排名 1 · LXL04_021464 · OH-1004

细胞核0.540

排名 2 · LXL04_021464 · OH-1004

细胞膜0.074

排名 3 · LXL04_021464 · OH-1004

内质网0.054

排名 4 · LXL04_021464 · OH-1004

线粒体0.050

排名 5 · LXL04_021464 · OH-1004

LocPro · 直接预测 · 计算预测，非定位实验结果

进入亚细胞定位查询

预测功能结构域

结构域结果来自 Pfam-A/HMMER；位置为对应蛋白序列上的氨基酸坐标。

PF00069.32Pkinase51-310 aa

PF07714.24PK_Tyr_Ser-Thr51-305 aa

PF03109.23ABC1123-195 aa

基因 ID	结构域编号	结构域名称	起始 aa	终止 aa	E 值	评分
LXL04_021464	`PF00069.32`	Pkinase	51	310	4.9e-68	230.1
LXL04_021464	`PF07714.24`	PK_Tyr_Ser-Thr	51	305	1.1e-38	133.7
LXL04_021464	`PF03109.23`	ABC1	123	195	9.6e-06	25.6

拟南芥 / 水稻蛋白同源

仅展示拟南芥和水稻；Swiss-Prot 为人工审校条目，TrEMBL 为补充序列候选。同源相似性不等同于实验验证。

下载当前结果

蛋白	物种	描述	一致性	数据库	置信等级
`Q9FX43`	拟南芥	Mitogen-activated protein kinase kinase 9	66.561%	Swiss-Prot	强数据库同源证据
`Q9LPQ3`	拟南芥	Mitogen-activated protein kinase kinase 7	60.883%	Swiss-Prot	强数据库同源证据
`Q9M8J5`	拟南芥	Mitogen-activated protein kinase kinase 8	50.943%	Swiss-Prot	强数据库同源证据
`Q8RXG3`	拟南芥	Mitogen-activated protein kinase kinase 5	51.648%	Swiss-Prot	强数据库同源证据
`O80397`	拟南芥	Mitogen-activated protein kinase kinase 4	47.531%	Swiss-Prot	中等数据库同源证据

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