Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

300 candidates match the current filter; 10 are shown per page (page 22 of 30). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA07G372950
TK1151: TkA07G372950
OH-1004: LXL04_030050
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:106413298-106414062
+
GO:0016114
LXL04_030052
TK1151: -
OH-1004: LXL04_030052
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:106440595-106442744
+
GO:0016114
TkA07G403060
TK1151: TkA07G403060
OH-1004: LXL04_030439
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:116024808-116025848
-
GO:0008299
TkA07G420160
TK1151: TkA07G420160
OH-1004: LXL04_030637
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:119967993-119969304
+
GO:0008299
TkA07G423210
TK1151: TkA07G423210;TkA08G104360
OH-1004: LXL04_030686
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:120783935-120785960
-
GO:0016740
TkA07G425430
TK1151: TkA07G425430
OH-1004: LXL04_030713
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:121251815-121254315
+
GO:0008299
LXL04_030753
TK1151: -
OH-1004: LXL04_030753
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:122082899-122083495
+
GO:0016114
TkA02G598320
TK1151: TkA02G598320;TkA03G537310;TkA07G428840
OH-1004: LXL04_030754
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:122085141-122089922
+
GO:0016114
LXL04_031032
TK1151: -
OH-1004: LXL04_031032
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:126968488-126969999
+
GO:0016740
TkA08G106070
TK1151: TkA08G106070
OH-1004: LXL04_031429
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:5820326-5823454
-
GO:0008299

TkA07G372950

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA07G372950
LocationCM104804.1:106413298-106414062 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

LXL04_030052

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104804.1:106440595-106442744 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA07G403060

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA07G403060
LocationCM104804.1:116024808-116025848 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA07G420160

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA07G420160
LocationCM104804.1:119967993-119969304 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA07G423210

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA07G423210;TkA08G104360
LocationCM104804.1:120783935-120785960 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA07G425430

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA07G425430
LocationCM104804.1:121251815-121254315 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

LXL04_030753

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104804.1:122082899-122083495 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA02G598320

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G598320;TkA03G537310;TkA07G428840
LocationCM104804.1:122085141-122089922 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

LXL04_031032

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104804.1:126968488-126969999 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA08G106070

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA08G106070
LocationCM104805.1:5820326-5823454 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.