Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 186 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA01G107400
TK1151: TkA01G107400;TkA04G117700
OH-1004: LXL04_004818
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:147513556-147516452
+
go:0009651 response to salt stress biological_process
TkA01G103080
TK1151: TkA01G103080
OH-1004: LXL04_004831
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationSwiss-ProtPPICoexpression CM104799.1:148385406-148394311
-
go:0009651 response to salt stress biological_process
TkA01G102670
TK1151: TkA01G102670
OH-1004: LXL04_004835
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationSwiss-ProtCoexpression CM104799.1:148472388-148473999
-
go:0048364 root development biological_process
TkA01G102400
TK1151: TkA01G102400
OH-1004: LXL04_004842
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:148544407-148545591
+
go:0009651 response to salt stress biological_process
TkA01G098920
TK1151: TkA01G098920
OH-1004: LXL04_004889
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:149615699-149618759
-
go:0043157 response to cation stress biological_process
TkA01G098140
TK1151: TkA01G098140
OH-1004: LXL04_004907
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:149962337-149965092
+
go:0009651 response to salt stress biological_process
TkA01G098070
TK1151: TkA01G098070;TkA02G548850;TkA08G365220
OH-1004: LXL04_004910
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:150005651-150009012
+
go:0009651 response to salt stress biological_process
TkAUNG023970
TK1151: TkAUNG023970;TkA01G097950;TkA03G057590;TkA03G084740;TkA03G084970
OH-1004: LXL04_004912
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:150040995-150042311
+
go:0010015 root morphogenesis biological_process
TkA01G096770
TK1151: TkA01G096770;TkA01G096950
OH-1004: LXL04_004922
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:150213195-150216277
-
go:0009611 response to wounding biological_process
LXL04_004937
TK1151: -
OH-1004: LXL04_004937
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationSwiss-ProtPPICoexpression CM104799.1:150590431-150593266
+
go:0048829 root cap development biological_process

TkA01G107400

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G107400;TkA04G117700
LocationCM104799.1:147513556-147516452 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA01G103080

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G103080
LocationCM104799.1:148385406-148394311 -
EvidenceGOExpressionLocalizationSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA01G102670

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G102670
LocationCM104799.1:148472388-148473999 -
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0048364 root development biological_process

TkA01G102400

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G102400
LocationCM104799.1:148544407-148545591 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA01G098920

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G098920
LocationCM104799.1:149615699-149618759 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0043157 response to cation stress biological_process

TkA01G098140

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G098140
LocationCM104799.1:149962337-149965092 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA01G098070

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G098070;TkA02G548850;TkA08G365220
LocationCM104799.1:150005651-150009012 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkAUNG023970

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkAUNG023970;TkA01G097950;TkA03G057590;TkA03G084740;TkA03G084970
LocationCM104799.1:150040995-150042311 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010015 root morphogenesis biological_process

TkA01G096770

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G096770;TkA01G096950
LocationCM104799.1:150213195-150216277 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

LXL04_004937

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source ID-
LocationCM104799.1:150590431-150593266 +
EvidenceGOExpressionLocalizationSwiss-ProtPPICoexpression
Key evidencego:0048829 root cap development biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.