Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 184 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA01G132610
TK1151: TkA01G132610;TkA06G140920
OH-1004: LXL04_004581
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:140980457-140981419
+
go:0071472 cellular response to salt stress biological_process
TkA01G131840
TK1151: TkA01G131840
OH-1004: LXL04_004593
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:141156022-141156624
+
go:0009611 response to wounding biological_process
LXL04_004616
TK1151: -
OH-1004: LXL04_004616
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:141645677-141647931
+
go:0010494 cytoplasmic stress granule cellular_component
TkA01G128770
TK1151: TkA01G128770
OH-1004: LXL04_004646
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:142355336-142358875
+
go:0048364 root development biological_process
TkA01G128710
TK1151: TkA01G128710
OH-1004: LXL04_004648
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:142373431-142376685
+
go:0010082 regulation of root meristem growth biological_process
LXL04_004650
TK1151: -
OH-1004: LXL04_004650
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:142409911-142411880
-
go:0048527 lateral root development biological_process
TkA01G128550
TK1151: TkA01G128550
OH-1004: LXL04_004655
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:142488041-142499980
-
go:0010086 embryonic root morphogenesis biological_process
TkAUNG001010
TK1151: TkAUNG001010;TkA01G127600;TkA08G185620
OH-1004: LXL04_004662
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:142664735-142666222
-
go:0009611 response to wounding biological_process
TkA01G122430
TK1151: TkA01G122430
OH-1004: LXL04_004689
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPI CM104799.1:143560275-143561730
+
go:0048829 root cap development biological_process
TkA01G119880
TK1151: TkA01G119880
OH-1004: LXL04_004708
Latex/root related candidates
Latex/root associated candidates
Low
score 2
GOExpressionLocalizationPfamSwiss-Prot CM104799.1:144276271-144276879
+
go:2000280 regulation of root development biological_process

TkA01G132610

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G132610;TkA06G140920
LocationCM104799.1:140980457-140981419 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0071472 cellular response to salt stress biological_process

TkA01G131840

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G131840
LocationCM104799.1:141156022-141156624 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

LXL04_004616

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source ID-
LocationCM104799.1:141645677-141647931 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010494 cytoplasmic stress granule cellular_component

TkA01G128770

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G128770
LocationCM104799.1:142355336-142358875 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0048364 root development biological_process

TkA01G128710

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G128710
LocationCM104799.1:142373431-142376685 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010082 regulation of root meristem growth biological_process

LXL04_004650

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source ID-
LocationCM104799.1:142409911-142411880 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0048527 lateral root development biological_process

TkA01G128550

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G128550
LocationCM104799.1:142488041-142499980 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010086 embryonic root morphogenesis biological_process

TkAUNG001010

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkAUNG001010;TkA01G127600;TkA08G185620
LocationCM104799.1:142664735-142666222 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkA01G122430

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G122430
LocationCM104799.1:143560275-143561730 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPI
Key evidencego:0048829 root cap development biological_process

TkA01G119880

Latex/root related candidatesLatex/root associated candidatesLow · score 2
Source IDTkA01G119880
LocationCM104799.1:144276271-144276879 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidencego:2000280 regulation of root development biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.