巴西橡胶树 · HRBP
序列 IDLC057267
步骤CPT/CPTL · CPTL
证据HRBP作为HRT1橡胶粒子复合体辅助亚基被报道。
边界Complex-support evidence, not a stand-alone catalytic claim.
橡胶生物合成专题
围绕 MVA/MEP、IPP/DMAPP、异戊二烯供体、CPT/CPTL、REF/SRPP、乳胶/根相关和萜类代谢，集中展示候选基因、证据等级、跨模块支持与下载入口。
本专题基于当前 GFF/GO/KEGG/同源注释预计算候选集合，并联动表达、蛋白组、亚细胞定位、Pfam、Swiss-Prot、PPI、共表达和 TFBS 等证据。所有结果为候选证据，不等同于实验证实的橡胶合成调控机制。
当前数据库收录 5523 条候选记录、4979 个候选基因和 8 个通路步骤；主显示以 TK1151 参考为中心，OH-1004/LXL04 参考仍可直接查询和跳转。
跨物种研究参考
此处的 22 条参考基因与橡胶草自身候选记录分开统计。它们来自巴西橡胶树、银胶菊、近缘蒲公英和杜仲的已发表实验、组学或序列资源；同源性或外源功能不等同于橡胶草中的直接验证。
1. 选择参照物种点击下方物种卡或使用筛选框，聚焦同一物种的参考基因和材料背景。
2. 查看证据类型优先查看“证据与边界”列：直接实验、组学关联和序列资源的可解释范围不同。
3. 核查原始来源每条记录的 DOI、论文或公共数据库入口均可点击；可下载当前筛选结果用于进一步比对。
杜仲记录仅作为反式聚异戊二烯（杜仲胶）对照，不计入天然顺式橡胶候选和通路卡片数量。
4巴西橡胶树点击查看 · 2 个来源 · cis-1,4-polyisoprene9银胶菊点击查看 · 4 个来源 · cis-1,4-polyisoprene8短角蒲公英点击查看 · 3 个来源 · cis-1,4-polyisoprene1杜仲点击查看 · 1 个来源 · trans-1,4-polyisoprene
| 物种与材料 | 参考基因/序列 ID | 通路步骤 | 证据与边界 | 来源 |
|---|---|---|---|---|
| 巴西橡胶树Hevea brasiliensiscis-1,4-polyisopreneRubber particles | HRBPLC057267CPTL | CPT/CPTLHRT1复合体辅助亚基 | A_direct_experiment HRBP作为HRT1橡胶粒子复合体辅助亚基被报道。 Complex-support evidence, not a stand-alone catalytic claim. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
| 巴西橡胶树Hevea brasiliensiscis-1,4-polyisopreneRubber particles | HRT1BAB71776.2;AB061234.3CPT | CPT/CPTL橡胶粒子上的顺式异戊二烯基转移酶 | A_direct_experiment HRT1在去污剂清洗的橡胶粒子上显示体外橡胶转移酶活性，HRT1-REF-HRBP复合体提高活性。 Direct evidence in Hevea rubber particles; not direct validation in rubber dandelion. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
| 银胶菊Parthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCBPMF688938;ATD87120CPTL | CPT/CPTL银胶菊CPT复合体辅助亚基 | A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Helper-subunit evidence must retain the assay context. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| 银胶菊Parthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCPT1MF688933;ATD87115CPT | CPT/CPTL与PaCBP形成顺式异戊二烯基转移酶复合物 | A_direct_experiment PaCPT1与PaCBP在异源和体外体系中形成有活性的顺式异戊二烯基转移酶复合物。 Assay-dependent external evidence; not in-plant rubber-yield proof. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| 银胶菊Parthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCPT2MF688936;ATD87118CPT | CPT/CPTL与PaCBP形成顺式异戊二烯基转移酶复合物 | A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Do not equate short-chain in-vitro activity with in-plant rubber yield. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| 银胶菊Parthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCPT3MF688934;ATD87116CPT | CPT/CPTL与PaCBP形成顺式异戊二烯基转移酶复合物 | A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Do not equate short-chain in-vitro activity with in-plant rubber yield. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| 短角蒲公英Taraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assays | TbCPT1JQ991925.1CPT | CPT/CPTL乳管特异顺式异戊二烯基转移酶 | A_direct_experiment TbCPT1为近缘蒲公英乳管特异顺式橡胶合成直接实验参考。 External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. | 10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum |
| 短角蒲公英Taraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assays | TbCPT2JQ991926.1CPT | CPT/CPTL乳管特异顺式异戊二烯基转移酶 | A_direct_experiment TbCPT2为近缘蒲公英乳管特异顺式橡胶合成直接实验参考。 External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. | 10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum |
| 短角蒲公英Taraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assays | TbCPT3JQ991927.1CPT | CPT/CPTL乳管特异顺式异戊二烯基转移酶 | A_direct_experiment TbCPT3为近缘蒲公英乳管特异顺式橡胶合成直接实验参考。 External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. | 10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum |
| 短角蒲公英Taraxacum brevicorniculatumcis-1,4-polyisopreneRubber-particle extraction and heterologous assays | TbSRPP1JQ991928.1SRPP | REF/SRPP 橡胶颗粒小橡胶粒子蛋白 | A_direct_experiment TbSRPP1为橡胶颗粒形成相关的直接实验参考。 External particle-protein evidence, not direct validation in T. kok-saghyz. | 10.1111/tpj.13829Small rubber particle proteins from Taraxacum brevicorniculatum are associated with rubber particle formation |
| 杜仲Eucommia ulmoidestrans-1,4-polyisopreneTransgenic roots | EuIPIAB041629.2IDI | 异戊二烯供体杜仲胶前体供给参考 | A_direct_genetic_experiment EuIPI过表达与反式聚异戊二烯积累增加相关。 Trans-polyisoprene comparator only; excluded from natural cis-rubber 候选 conclusions. | 10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation |
| 银胶菊Parthenium argentatumcis-1,4-polyisopreneAOS RNAi and overexpression plants | AOS1X78166.2CYP74 | 乳胶/根相关影响橡胶含量与橡胶转移酶活性的调控候选 | A_direct_genetic_experiment AOS下调与橡胶含量和橡胶转移酶活性升高相关。 RNAi specificity limitation remains; do not infer a single-gene universal mechanism. | 10.3389/fpls.2019.00760Silencing of allene oxide synthase in guayule increases rubber content and rubber transferase activity |
| 巴西橡胶树Hevea brasiliensiscis-1,4-polyisopreneLatex and recombinant enzyme | HRT2Q8W3U4;AB064661.2CPT | CPT/CPTL乳胶表达的顺式异戊二烯基转移酶参考 | A_enzyme_experiment HRT2为顺式异戊二烯基转移酶和乳胶表达参考。 Do not claim direct reconstitution of 高置信-molecular-weight natural rubber by HRT2 alone. | 10.1046/j.1432-1033.2003.03863.xMolecular cloning expression and characterization of cDNA encoding cis-prenyltransferases from Hevea brasiliensis |
| 巴西橡胶树Hevea brasiliensiscis-1,4-polyisopreneRubber particles | REFREF complex memberREF | REF/SRPP 橡胶颗粒橡胶粒子复合体成员 | A_complex_evidence HRT1 and HRBP/REF particle-complex evidence; REF is not displayed as a stand-alone catalytic proof. Not a stand-alone catalytic proof. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
| 银胶菊Parthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions | PaCBPPaTc_149493CPTL | CPT/CPTL干旱组学中的CBP转录本参考 | B_omics_association PaCBP在田间水分处理茎皮转录组中被报道。 Association only; transcript abundance is not direct proof of rubber yield. | 10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions |
| 银胶菊Parthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions | PaCPT1PaTc_044561CPT | CPT/CPTL干旱组学中的CPT1转录本参考 | B_omics_association PaCPT1在田间水分处理茎皮转录组中被报道。 Association only; transcript abundance is not direct proof of rubber yield. | 10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions |
| 银胶菊Parthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions | PaSRPP1PaTc_109994SRPP | REF/SRPP 橡胶颗粒干旱组学中的SRPP1转录本参考 | B_omics_association 表达关联不能直接作为橡胶产量因果证据。 转录本丰度不是橡胶产量的直接证明。 | 10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions |
| 银胶菊Parthenium argentatumcis-1,4-polyisopreneSRPP1 promoter reporter assay | PaSRPP1 promoterPV754023.1SRPP | REF/SRPP 橡胶颗粒SRPP1启动子调控参考 | A_promoter_experiment Promoter sequence is regulatory reference evidence, not a complete gene-model crosswalk. Promoter record is not a complete SRPP1 gene model. | 10.1186/s13104-025-07448-0Functional characterization of the guayule SRPP1 promoter |
| 短角蒲公英Taraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbRTAKP763637.1RTA | 乳胶/根相关橡胶转移酶激活因子参考 | B_sequence_resource 序列记录支持精确 ID 查询和后续同源比对，但不能单独证明功能。 单条序列记录本身不是功能证明。 | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
| 短角蒲公英Taraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbFDPS1KJ911908.1FDPS | 异戊二烯供体异戊二烯供体合成参考 | B_sequence_resource 序列记录支持精确 ID 查询和后续同源比对，但不能单独证明功能。 单条序列记录本身不是功能证明。 | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
| 短角蒲公英Taraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbFDPS2KJ911910.1FDPS | 异戊二烯供体异戊二烯供体合成参考 | B_sequence_resource 序列记录支持精确 ID 查询和后续同源比对，但不能单独证明功能。 单条序列记录本身不是功能证明。 | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
| 短角蒲公英Taraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbREFMF471639.1REF | REF/SRPP 橡胶颗粒橡胶粒子蛋白参考 | B_sequence_resource 序列记录支持精确 ID 查询和后续同源比对，但不能单独证明功能。 单条序列记录本身不是功能证明。 | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
巴西橡胶树 · HRBP
巴西橡胶树 · HRT1
银胶菊 · PaCBP
银胶菊 · PaCPT1
银胶菊 · PaCPT2
银胶菊 · PaCPT3
短角蒲公英 · TbCPT1
短角蒲公英 · TbCPT2
短角蒲公英 · TbCPT3
短角蒲公英 · TbSRPP1
杜仲 · EuIPI
银胶菊 · AOS1
巴西橡胶树 · HRT2
巴西橡胶树 · REF
银胶菊 · PaCBP
银胶菊 · PaCPT1
银胶菊 · PaSRPP1
银胶菊 · PaSRPP1 promoter
短角蒲公英 · TbRTA
短角蒲公英 · TbFDPS1
短角蒲公英 · TbFDPS2
短角蒲公英 · TbREF
通路导航与候选分布
MVA · MVA 甲羟戊酸途径
47
High 40 · Medium 3 · Low 4
MEP · MEP 非甲羟戊酸途径
59
High 23 · Medium 0 · Low 36
IPP/DMAPP/FPP · 异戊二烯供体
271
High 141 · Medium 83 · Low 47
CPT/CPTL · 顺式异戊二烯转移酶
5
High 0 · Medium 0 · Low 5
REF/SRPP · 橡胶颗粒相关蛋白
7
High 0 · Medium 0 · Low 7
Rubber · 橡胶生物合成
288
High 1 · Medium 287 · Low 0
Terpenoid · 萜类代谢
380
High 72 · Medium 107 · Low 201
Latex/root · 乳胶/根相关候选
4466
High 231 · Medium 1284 · Low 2951
候选基因表
当前筛选共 271 条候选，每页显示 10 条；当前为第 1/28 页。下载按钮导出当前筛选条件下最多 2000 条记录。点击上方通路卡或统计卡可快速筛选，证据摘要可通过基因详情和关联模块继续核查。
| 基因 ID | 通路/步骤 | 等级 | 证据层 | 位置 | 关键证据 | 操作 |
|---|---|---|---|---|---|---|
TkA03G462260TK1151: TkA03G462260 OH-1004: LXL04_009683 |
MVA/MEP 与异戊二烯 异戊二烯供体 |
高置信 分数 38 |
功能注释GO表达定位PfamSwiss-ProtPPI共表达 | CM104800.1:131179279-131183781 + |
GO:0006720 | |
LXL04_016664TK1151: - OH-1004: LXL04_016664 |
MVA/MEP 与异戊二烯 异戊二烯供体 |
高置信 分数 38 |
功能注释GO表达定位PfamSwiss-ProtPPI共表达 | CM104801.1:130385702-130391884 + |
GO:0006720 | |
TkA06G134330TK1151: TkA06G134330 OH-1004: LXL04_024531 |
MVA/MEP 与异戊二烯 异戊二烯供体 |
高置信 分数 36 |
功能注释GO表达定位PfamSwiss-ProtPPI共表达 | CM104803.1:93159005-93160081 - |
GO:0006720 | |
TkA06G097970TK1151: TkA06G097970 OH-1004: LXL04_024888 |
MVA/MEP 与异戊二烯 异戊二烯供体 |
高置信 分数 36 |
功能注释GO表达定位PfamSwiss-ProtPPI共表达 | CM104803.1:101545925-101547031 + |
GO:0006720 | |
TkA07G403060TK1151: TkA07G403060 OH-1004: LXL04_030439 |
MVA/MEP 与异戊二烯 异戊二烯供体 |
高置信 分数 36 |
功能注释GO表达定位PfamSwiss-ProtPPI共表达 | CM104804.1:116024808-116025848 - |
GO:0006720 | |
LXL04_032929TK1151: - OH-1004: LXL04_032929 |
MVA/MEP 与异戊二烯 异戊二烯供体 |
高置信 分数 36 |
功能注释GO表达定位Swiss-Prot | CM104805.1:31835394-31835726 - |
GO:0006720 | |
LXL04_039196TK1151: - OH-1004: LXL04_039196 |
MVA/MEP 与异戊二烯 异戊二烯供体 |
高置信 分数 36 |
功能注释GO表达定位Swiss-Prot | CM104807.1:62056370-62056955 - |
GO:0008299 | |
TkA02G159610TK1151: TkA02G159610;TkA02G159720 OH-1004: LXL04_016299 |
MVA/MEP 与异戊二烯 异戊二烯供体 |
高置信 分数 30 |
功能注释GO表达定位Swiss-Prot共表达 | CM104801.1:117805721-117806576 + |
GO:0008299 | |
TkA01G191830TK1151: TkA01G191830 OH-1004: LXL04_004171 |
MVA/MEP 与异戊二烯 异戊二烯供体 |
高置信 分数 22 |
功能注释GO表达定位PfamSwiss-ProtPPI共表达 | CM104799.1:127302658-127304505 + |
go:0004311 geranylgeranyl diphosphate synthase activity 分子功能 | |
TkA01G499770TK1151: TkA01G499770 OH-1004: LXL04_001903 |
MVA/MEP 与异戊二烯 异戊二烯供体 |
高置信 分数 16 |
GO表达定位PfamSwiss-ProtPPI共表达 | CM104799.1:36531195-36533379 - |
GO:0008299 |
证据边界
当前结果来自注释、GO/KEGG、同源、预测定位、结构域、表达/蛋白组和网络数据库的整合候选证据。High/Medium/Low 表示数据库证据密度和一致性，不代表已经完成湿实验验证；乳胶/根相关集合是候选背景，不应直接解读为橡胶生物合成酶。