Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 107 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
LXL04_033675
TK1151: -
OH-1004: LXL04_033675
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:52686546-52687328
+
GO:0016114
TkA08G297840
TK1151: TkA08G297840;TkA08G298110;TkA08G298800
OH-1004: LXL04_033676
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:52736712-52740252
+
GO:0016114
TkA02G044500
TK1151: TkA02G044500;TkA02G420680;TkA08G186450;TkA08G188290
OH-1004: LXL04_033693
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:53482628-53484208
+
GO:0016740
LXL04_033810
TK1151: -
OH-1004: LXL04_033810
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104805.1:58972906-58973696
-
go:0006970 response to osmotic stress biological_process
TkA01G606560
TK1151: TkA01G606560
OH-1004: LXL04_033849
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104805.1:60877345-60878149
-
GO:0016740
TkA01G542510
TK1151: TkA01G542510;TkA05G071810;TkA08G312800
OH-1004: LXL04_033892
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-Prot CM104805.1:63607614-63608216
+
GO:0016740
LXL04_033945
TK1151: -
OH-1004: LXL04_033945
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:67660599-67661005
+
GO:0016114
LXL04_033947
TK1151: -
OH-1004: LXL04_033947
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:67678877-67679283
+
GO:0016114
LXL04_034177
TK1151: -
OH-1004: LXL04_034177
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPI CM104805.1:87438763-87439404
-
go:0010311 lateral root formation biological_process
TkA02G397010
TK1151: TkA02G397010;TkA02G397070;TkA03G577920;TkA05G053790;TkA05G054080
OH-1004: LXL04_034492
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:102913696-102917110
-
go:0010334 sesquiterpene synthase activity molecular_function

LXL04_033675

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104805.1:52686546-52687328 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA08G297840

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA08G297840;TkA08G298110;TkA08G298800
LocationCM104805.1:52736712-52740252 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA02G044500

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G044500;TkA02G420680;TkA08G186450;TkA08G188290
LocationCM104805.1:53482628-53484208 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

LXL04_033810

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source ID-
LocationCM104805.1:58972906-58973696 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA01G606560

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G606560
LocationCM104805.1:60877345-60878149 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA01G542510

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G542510;TkA05G071810;TkA08G312800
LocationCM104805.1:63607614-63608216 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidenceGO:0016740

LXL04_033945

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104805.1:67660599-67661005 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

LXL04_033947

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104805.1:67678877-67679283 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

LXL04_034177

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source ID-
LocationCM104805.1:87438763-87439404 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPI
Key evidencego:0010311 lateral root formation biological_process

TkA02G397010

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA02G397010;TkA02G397070;TkA03G577920;TkA05G053790;TkA05G054080
LocationCM104805.1:102913696-102917110 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010334 sesquiterpene synthase activity molecular_function

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.