species_code scientific_name polymer_class reference_gene source_gene_ids family pathway_step evidence_level claim evidence_boundary source_title doi pmid accession source_url material_context HB Hevea brasiliensis cis-1,4-polyisoprene HRBP LC057267 CPTL cpt_cptl A_direct_experiment HRBP作为HRT1橡胶粒子复合体辅助亚基被报道。 Complex-support evidence, not a stand-alone catalytic claim. Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis 10.7554/eLife.19022 27790974 BAB71776.2;AB061234.3;LC057267 https://doi.org/10.7554/eLife.19022 Rubber particles HB Hevea brasiliensis cis-1,4-polyisoprene HRT1 BAB71776.2;AB061234.3 CPT cpt_cptl A_direct_experiment HRT1在去污剂清洗的橡胶粒子上显示体外橡胶转移酶活性，HRT1-REF-HRBP复合体提高活性。 Direct evidence in Hevea rubber particles; not direct validation in rubber dandelion. Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis 10.7554/eLife.19022 27790974 BAB71776.2;AB061234.3;LC057267 https://doi.org/10.7554/eLife.19022 Rubber particles PA Parthenium argentatum cis-1,4-polyisoprene PaCBP MF688938;ATD87120 CPTL cpt_cptl A_direct_experiment Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule 10.3389/fpls.2019.00165 MF688933;MF688934;MF688936;MF688938;SRP107961 https://pmc.ncbi.nlm.nih.gov/articles/PMC6397875/ PI478663 and heterologous systems PA Parthenium argentatum cis-1,4-polyisoprene PaCPT1 MF688933;ATD87115 CPT cpt_cptl A_direct_experiment PaCPT1与PaCBP在异源和体外体系中形成有活性的顺式异戊二烯基转移酶复合物。 Assay-dependent external evidence; not in-plant rubber-yield proof. Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule 10.3389/fpls.2019.00165 MF688933;MF688934;MF688936;MF688938;SRP107961 https://pmc.ncbi.nlm.nih.gov/articles/PMC6397875/ PI478663 and heterologous systems PA Parthenium argentatum cis-1,4-polyisoprene PaCPT2 MF688936;ATD87118 CPT cpt_cptl A_direct_experiment Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule 10.3389/fpls.2019.00165 MF688933;MF688934;MF688936;MF688938;SRP107961 https://pmc.ncbi.nlm.nih.gov/articles/PMC6397875/ PI478663 and heterologous systems PA Parthenium argentatum cis-1,4-polyisoprene PaCPT3 MF688934;ATD87116 CPT cpt_cptl A_direct_experiment Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule 10.3389/fpls.2019.00165 MF688933;MF688934;MF688936;MF688938;SRP107961 https://pmc.ncbi.nlm.nih.gov/articles/PMC6397875/ PI478663 and heterologous systems TB Taraxacum brevicorniculatum cis-1,4-polyisoprene TbCPT1 JQ991925.1 CPT cpt_cptl A_direct_experiment TbCPT1为近缘蒲公英乳管特异顺式橡胶合成直接实验参考。 External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum 10.1104/pp.111.187880 22238421 JQ991925.1;JQ991926.1;JQ991927.1 https://doi.org/10.1104/pp.111.187880 RNAi laticifers with polymer and particle assays TB Taraxacum brevicorniculatum cis-1,4-polyisoprene TbCPT2 JQ991926.1 CPT cpt_cptl A_direct_experiment TbCPT2为近缘蒲公英乳管特异顺式橡胶合成直接实验参考。 External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum 10.1104/pp.111.187880 22238421 JQ991925.1;JQ991926.1;JQ991927.1 https://doi.org/10.1104/pp.111.187880 RNAi laticifers with polymer and particle assays TB Taraxacum brevicorniculatum cis-1,4-polyisoprene TbCPT3 JQ991927.1 CPT cpt_cptl A_direct_experiment TbCPT3为近缘蒲公英乳管特异顺式橡胶合成直接实验参考。 External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum 10.1104/pp.111.187880 22238421 JQ991925.1;JQ991926.1;JQ991927.1 https://doi.org/10.1104/pp.111.187880 RNAi laticifers with polymer and particle assays TB Taraxacum brevicorniculatum cis-1,4-polyisoprene TbSRPP1 JQ991928.1 SRPP rubber_particle A_direct_experiment TbSRPP1为橡胶颗粒形成相关的直接实验参考。 External particle-protein evidence, not direct validation in T. kok-saghyz. Small rubber particle proteins from Taraxacum brevicorniculatum are associated with rubber particle formation 10.1111/tpj.13829 JQ991928.1;JQ991929.1;JQ991930.1;JQ991931.1;JQ991932.1 https://doi.org/10.1111/tpj.13829 Rubber-particle extraction and heterologous assays EU Eucommia ulmoides trans-1,4-polyisoprene EuIPI AB041629.2 IDI prenyl_donor A_direct_genetic_experiment EuIPI过表达与反式聚异戊二烯积累增加相关。 Trans-polyisoprene comparator only; excluded from natural cis-rubber 候选 conclusions. Overexpression of EuIPI increases trans-polyisoprene accumulation 10.1186/1472-6750-12-78 23110380 AB041629.2 https://doi.org/10.1186/1472-6750-12-78 Transgenic roots PA Parthenium argentatum cis-1,4-polyisoprene AOS1 X78166.2 CYP74 latex_root A_direct_genetic_experiment AOS下调与橡胶含量和橡胶转移酶活性升高相关。 RNAi specificity limitation remains; do not infer a single-gene universal mechanism. Silencing of allene oxide synthase in guayule increases rubber content and rubber transferase activity 10.3389/fpls.2019.00760 X78166.2 https://pmc.ncbi.nlm.nih.gov/articles/PMC6607968/ AOS RNAi and overexpression plants HB Hevea brasiliensis cis-1,4-polyisoprene HRT2 Q8W3U4;AB064661.2 CPT cpt_cptl A_enzyme_experiment HRT2为顺式异戊二烯基转移酶和乳胶表达参考。 Do not claim direct reconstitution of 高置信-molecular-weight natural rubber by HRT2 alone. Molecular cloning expression and characterization of cDNA encoding cis-prenyltransferases from Hevea brasiliensis 10.1046/j.1432-1033.2003.03863.x 14622254 AB061234.3;AB064661.2 https://doi.org/10.1046/j.1432-1033.2003.03863.x Latex and recombinant enzyme HB Hevea brasiliensis cis-1,4-polyisoprene REF REF complex member REF rubber_particle A_complex_evidence Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis 10.7554/eLife.19022 27790974 BAB71776.2;AB061234.3;LC057267 https://doi.org/10.7554/eLife.19022 Rubber particles PA Parthenium argentatum cis-1,4-polyisoprene PaCBP PaTc_149493 CPTL cpt_cptl B_omics_association PaCBP在田间水分处理茎皮转录组中被报道。 Association only; transcript abundance is not direct proof of rubber yield. Transcriptomic analysis of guayule bark under contrasting irrigation conditions 10.1038/s41598-021-01026-7 PRJNA400611 https://pmc.ncbi.nlm.nih.gov/articles/PMC8566568/ AZ-3 field bark under well-watered and drought conditions PA Parthenium argentatum cis-1,4-polyisoprene PaCPT1 PaTc_044561 CPT cpt_cptl B_omics_association PaCPT1在田间水分处理茎皮转录组中被报道。 Association only; transcript abundance is not direct proof of rubber yield. Transcriptomic analysis of guayule bark under contrasting irrigation conditions 10.1038/s41598-021-01026-7 PRJNA400611 https://pmc.ncbi.nlm.nih.gov/articles/PMC8566568/ AZ-3 field bark under well-watered and drought conditions PA Parthenium argentatum cis-1,4-polyisoprene PaSRPP1 PaTc_109994 SRPP rubber_particle B_omics_association Transcriptomic analysis of guayule bark under contrasting irrigation conditions 10.1038/s41598-021-01026-7 PRJNA400611 https://pmc.ncbi.nlm.nih.gov/articles/PMC8566568/ AZ-3 field bark under well-watered and drought conditions PA Parthenium argentatum cis-1,4-polyisoprene PaSRPP1 promoter PV754023.1 SRPP rubber_particle A_promoter_experiment Functional characterization of the guayule SRPP1 promoter 10.1186/s13104-025-07448-0 PV754023.1 https://pmc.ncbi.nlm.nih.gov/articles/PMC12406399/ SRPP1 promoter reporter assay TB Taraxacum brevicorniculatum cis-1,4-polyisoprene TbRTA KP763637.1 RTA latex_root B_sequence_resource Taraxacum brevicorniculatum rubber pathway sequence records KP763637.1;MF471639.1;KJ911908.1;KJ911910.1 https://www.ncbi.nlm.nih.gov/nuccore/JQ991925.1 Public cDNA records TB Taraxacum brevicorniculatum cis-1,4-polyisoprene TbFDPS1 KJ911908.1 FDPS prenyl_donor B_sequence_resource Taraxacum brevicorniculatum rubber pathway sequence records KP763637.1;MF471639.1;KJ911908.1;KJ911910.1 https://www.ncbi.nlm.nih.gov/nuccore/JQ991925.1 Public cDNA records TB Taraxacum brevicorniculatum cis-1,4-polyisoprene TbFDPS2 KJ911910.1 FDPS prenyl_donor B_sequence_resource Taraxacum brevicorniculatum rubber pathway sequence records KP763637.1;MF471639.1;KJ911908.1;KJ911910.1 https://www.ncbi.nlm.nih.gov/nuccore/JQ991925.1 Public cDNA records TB Taraxacum brevicorniculatum cis-1,4-polyisoprene TbREF MF471639.1 REF rubber_particle B_sequence_resource Taraxacum brevicorniculatum rubber pathway sequence records KP763637.1;MF471639.1;KJ911908.1;KJ911910.1 https://www.ncbi.nlm.nih.gov/nuccore/JQ991925.1 Public cDNA records