query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
TkA07G106970	TkA07G106970	TkA07G106970.1	TK1151	2	P49597	P2C56_ARATH	Swiss-Prot		sp|P49597|P2C56_ARATH Protein phosphatase 2C 56	Arabidopsis thaliana	ABI1	50.0	308	76.658	4.68e-90	280.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At4g26080	脱落酸（ABA）信号通路的关键组分和抑制因子，调控众多ABA反应，如气孔关闭、质膜渗透水性（Pos）、干旱诱导的抗性和根形成、对葡萄糖的响应、高光胁迫、种子发芽以及营养生长抑制。	Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), drought-induced resistance and rhizogenesis, response to glucose, high light stress, seed germination and inhibition of vegetative growth.	"[{""pmid"":""10488243"",""title"":""Arabidopsis abi1-1 and abi2-1 phosphatase mutations reduce abscisic acid-induced cytoplasmic calcium rises in guard cells."",""doi"":""10.1105/tpc.11.9.1785"",""url"":""https://pubmed.ncbi.nlm.nih.gov/10488243/"",""year"":""1999"",""journal"":""The Plant cell"",""authors"":""Allen GJ; Kuchitsu K; Chu SP; Murata Y; Schroeder JI"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""10521520"",""title"":""ABI1 protein phosphatase 2C is a negative regulator of abscisic acid signaling."",""doi"":""10.1105/tpc.11.10.1897"",""url"":""https://pubmed.ncbi.nlm.nih.gov/10521520/"",""year"":""1999"",""journal"":""The Plant cell"",""authors"":""Gosti F; Beaudoin N; Serizet C; Webb AA; Vartanian N; Giraudat J"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""10645425"",""title"":""The role of ABI1 in abscisic acid signal transduction: from gene to cell."",""doi"":"""",""url"":""https://pubmed.ncbi.nlm.nih.gov/10645425/"",""year"":""1998"",""journal"":""Symposia of the Society for Experimental Biology"",""authors"":""Leung J; Merlot S; Gosti F; Bertauche N; Blatt MR; Giraudat J"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""10872217"",""title"":""The genes ABI1 and ABI2 are involved in abscisic acid- and drought-inducible expression of the Daucus carota L. Dc3 promoter in guard cells of transgenic Arabidopsis thaliana (L.) Heynh."",""doi"":""10.1007/s004250050692"",""url"":""https://pubmed.ncbi.nlm.nih.gov/10872217/"",""year"":""2000"",""journal"":""Planta"",""authors"":""Chak RK; Thomas TL; Quatrano RS; Rock CD"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""10950871"",""title"":""Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar."",""doi"":"""",""url"":""https://pubmed.ncbi.nlm.nih.gov/10950871/"",""year"":""2000"",""journal"":""Genes & development"",""authors"":""Arenas-Huertero F; Arroyo A; Zhou L; Sheen J; León P"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""11208021"",""title"":""The ABI1 and ABI2 protein phosphatases 2C act in a negative feedback regulatory loop of the abscisic acid signalling pathway."",""doi"":""10.1046/j.1365-313x.2001.00965.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11208021/"",""year"":""2001"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Merlot S; Gosti F; Guerrier D; Vavasseur A; Giraudat J"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""11289613"",""title"":""Cortical actin filaments in guard cells respond differently to abscisic acid in wild-type and abi1-1 mutant Arabidopsis."",""doi"":""10.1007/s004250000489"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11289613/"",""year"":""2001"",""journal"":""Planta"",""authors"":""Eun SO; Bae SH; Lee Y"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""11587514"",""title"":""Dissection of abscisic acid signal transduction pathways in barley aleurone layers."",""doi"":""10.1023/a:1011667312754"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11587514/"",""year"":""2001"",""journal"":""Plant molecular biology"",""authors"":""Shen Q; Gomez-Cadenas A; Zhang P; Walker-Simmons MK; Sheen J; Ho TH"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""11701885"",""title"":""Abscisic acid activation of plasma membrane Ca(2+) channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in abi1-1 and abi2-1 protein phosphatase 2C mutants."",""doi"":""10.1105/tpc.010210"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11701885/"",""year"":""2001"",""journal"":""The Plant cell"",""authors"":""Murata Y; Pei ZM; Mori IC; Schroeder J"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""11707572"",""title"":""The role of ABA and the transpiration stream in the regulation of the osmotic water permeability of leaf cells."",""doi"":""10.1073/pnas.231471998"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11707572/"",""year"":""2001"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Morillon R; Chrispeels MJ"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""12047634"",""title"":""Use of infrared thermal imaging to isolate Arabidopsis mutants defective in stomatal regulation."",""doi"":""10.1046/j.1365-313x.2002.01322.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12047634/"",""year"":""2002"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Merlot S, Mustilli AC, Genty B, North H, Lefebvre V, Sotta B, Vavasseur A, Giraudat J."",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""12065416"",""title"":""Homeodomain protein ATHB6 is a target of the protein phosphatase ABI1 and regulates hormone responses in Arabidopsis."",""doi"":""10.1093/emboj/cdf316"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12065416/"",""year"":""2002"",""journal"":""The EMBO journal"",""authors"":""Himmelbach A, Hoffmann T, Leube M, Höhener B, Grill E."",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; 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Lang V; Palva ET"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""12232124"",""title"":""Drought Rhizogenesis in Arabidopsis thaliana (Differential Responses of Hormonal Mutants)."",""doi"":""10.1104/pp.104.2.761"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12232124/"",""year"":""1994"",""journal"":""Plant physiology"",""authors"":""Vartanian N; Marcotte L; Giraudat J"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""12232276"",""title"":""Maternal Effects Govern Variable Dominance of Two Abscisic Acid Response Mutations in Arabidopsis thaliana."",""doi"":""10.1104/pp.105.4.1203"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12232276/"",""year"":""1994"",""journal"":""Plant physiology"",""authors"":""Finkelstein RR"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; 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Ball L; Oxborough K; Karpinski S; Mullineaux PM; Baker NR"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""12713537"",""title"":""The abi1-1 mutation blocks ABA signaling downstream of cADPR action."",""doi"":""10.1046/j.1365-313x.2003.01721.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12713537/"",""year"":""2003"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Wu Y; Sanchez JP; Lopez-Molina L; Himmelbach A; Grill E; Chua NH"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""14576281"",""title"":""Synthesis of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is concertedly regulated by metabolic and stress-associated signals."",""doi"":""10.1104/pp.103.026294"",""url"":""https://pubmed.ncbi.nlm.nih.gov/14576281/"",""year"":""2003"",""journal"":""Plant physiology"",""authors"":""Stepansky A; Galili G"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""14596925"",""title"":""Regulation of the ABA-sensitive Arabidopsis potassium channel gene GORK in response to water stress."",""doi"":""10.1016/s0014-5793(03)01118-9"",""url"":""https://pubmed.ncbi.nlm.nih.gov/14596925/"",""year"":""2003"",""journal"":""FEBS letters"",""authors"":""Becker D; Hoth S; Ache P; Wenkel S; Roelfsema MR; Meyerhoff O; Hartung W; Hedrich R"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""15197253"",""title"":""Phospholipase D alpha 1-derived phosphatidic acid interacts with ABI1 phosphatase 2C and regulates abscisic acid signaling."",""doi"":""10.1073/pnas.0402112101"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15197253/"",""year"":""2004"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Zhang W; Qin C; Zhao J; Wang X"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""15618419"",""title"":""Generation of active pools of abscisic acid revealed by in vivo imaging of water-stressed Arabidopsis."",""doi"":""10.1104/pp.104.053082"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15618419/"",""year"":""2005"",""journal"":""Plant physiology"",""authors"":""Christmann A; Hoffmann T; Teplova I; Grill E; Müller A"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""15923322"",""title"":""Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance."",""doi"":""10.1104/pp.105.062257"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15923322/"",""year"":""2005"",""journal"":""Plant physiology"",""authors"":""Larkindale J; Hall JD; Knight MR; Vierling E"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""16339784"",""title"":""Role of abscisic acid (ABA) and Arabidopsis thaliana ABA-insensitive loci in low water potential-induced ABA and proline accumulation."",""doi"":""10.1093/jxb/erj026"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16339784/"",""year"":""2006"",""journal"":""Journal of experimental botany"",""authors"":""Verslues PE; Bray EA"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""16365038"",""title"":""The regulatory domain of SRK2E/OST1/SnRK2.6 interacts with ABI1 and integrates abscisic acid (ABA) and osmotic stress signals controlling stomatal closure in Arabidopsis."",""doi"":""10.1074/jbc.m509820200"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16365038/"",""year"":""2006"",""journal"":""The Journal of biological chemistry"",""authors"":""Yoshida R, Umezawa T, Mizoguchi T, Takahashi S, Takahashi F, Shinozaki K."",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; 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Robert N; Maktabi MH; Schroeder JI; Serrano R; Rodriguez PL"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""17158582"",""title"":""Abscisic acid antagonizes ethylene-induced hyponastic growth in Arabidopsis."",""doi"":""10.1104/pp.106.092700"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17158582/"",""year"":""2007"",""journal"":""Plant physiology"",""authors"":""Benschop JJ; Millenaar FF; Smeets ME; van Zanten M; Voesenek LA; Peeters AJ"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""17304219"",""title"":""Pseudomonas syringae pv. tomato hijacks the Arabidopsis abscisic acid signalling pathway to cause disease."",""doi"":""10.1038/sj.emboj.7601575"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17304219/"",""year"":""2007"",""journal"":""The EMBO journal"",""authors"":""de Torres-Zabala M; Truman W; Bennett MH; Lafforgue G; Mansfield JW; Rodriguez Egea P; Bögre L; Grant M"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""18298671"",""title"":""Nuclear localization of the mutant protein phosphatase abi1 is required for insensitivity towards ABA responses in Arabidopsis."",""doi"":""10.1111/j.1365-313x.2008.03454.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/18298671/"",""year"":""2008"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Moes D; Himmelbach A; Korte A; Haberer G; Grill E"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""1834244"",""title"":""Cold acclimation and cold-regulated gene expression in ABA mutants of Arabidopsis thaliana."",""doi"":""10.1007/bf00028738"",""url"":""https://pubmed.ncbi.nlm.nih.gov/1834244/"",""year"":""1991"",""journal"":""Plant molecular biology"",""authors"":""Gilmour SJ; Thomashow MF"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""24179127"",""title"":""ABI1 and PP2CA phosphatases are negative regulators of Snf1-related protein kinase1 signaling in Arabidopsis."",""doi"":""10.1105/tpc.113.114066"",""url"":""https://pubmed.ncbi.nlm.nih.gov/24179127/"",""year"":""2013"",""journal"":""The Plant cell"",""authors"":""Rodrigues A, Adamo M, Crozet P, Margalha L, Confraria A, Martinho C, Elias A, Rabissi A, Lumbreras V, González-Guzmán M, Antoni R, Rodriguez PL, Baena-González E."",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""26443375"",""title"":""Arabidopsis ABA-Activated Kinase MAPKKK18 is Regulated by Protein Phosphatase 2C ABI1 and the Ubiquitin-Proteasome Pathway."",""doi"":""10.1093/pcp/pcv146"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26443375/"",""year"":""2015"",""journal"":""Plant & cell physiology"",""authors"":""Mitula F, Tajdel M, Cieśla A, Kasprowicz-Maluśki A, Kulik A, Babula-Skowrońska D, Michalak M, Dobrowolska G, Sadowski J, Ludwików A."",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; 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Leung J; Grabov A; Brearley J; Giraudat J; Blatt MR"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""8492808"",""title"":""Abscisic acid-insensitive mutations provide evidence for stage-specific signal pathways regulating expression of an Arabidopsis late embryogenesis-abundant (lea) gene."",""doi"":""10.1007/bf00291999"",""url"":""https://pubmed.ncbi.nlm.nih.gov/8492808/"",""year"":""1993"",""journal"":""Molecular & general genetics : MGG"",""authors"":""Finkelstein RR"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""8771791"",""title"":""The Arabidopsis homeobox gene ATHB-7 is induced by water deficit and by abscisic acid."",""doi"":""10.1046/j.1365-313x.1996.10020375.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/8771791/"",""year"":""1996"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Söderman E, Mattsson J, Engström P."",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; 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Kuchitsu K; Ward JM; Schwarz M; Schroeder JI"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9108297"",""title"":""Abscisic acid-independent and abscisic acid-dependent regulation of proline biosynthesis following cold and osmotic stresses in Arabidopsis thaliana."",""doi"":""10.1007/s004380050397"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9108297/"",""year"":""1997"",""journal"":""Molecular & general genetics : MGG"",""authors"":""Savouré A; Hua XJ; Bertauche N; Van Montagu M; Verbruggen N"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9161030"",""title"":""Interactions between the ABI1 and the ectopically expressed ABI3 genes in controlling abscisic acid responses in Arabidopsis vegetative tissues."",""doi"":""10.1046/j.1365-313x.1997.11040693.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9161030/"",""year"":""1997"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Parcy F; Giraudat J"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9165752"",""title"":""The Arabidopsis ABSCISIC ACID-INSENSITIVE2 (ABI2) and ABI1 genes encode homologous protein phosphatases 2C involved in abscisic acid signal transduction."",""doi"":""10.1105/tpc.9.5.759"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9165752/"",""year"":""1997"",""journal"":""The Plant cell"",""authors"":""Leung J; Merlot S; Giraudat J"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9263461"",""title"":""Alteration of anion channel kinetics in wild-type and abi1-1 transgenic Nicotiana benthamiana guard cells by abscisic acid."",""doi"":""10.1046/j.1365-313x.1997.12010203.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9263461/"",""year"":""1997"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Grabov A; Leung J; Giraudat J; Blatt MR"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9276963"",""title"":""Convergence of the abscisic acid, CO2, and extracellular calcium signal transduction pathways in stomatal guard cells."",""doi"":""10.1104/pp.114.4.1557"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9276963/"",""year"":""1997"",""journal"":""Plant physiology"",""authors"":""Webb AA; Hetherington AM"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9351242"",""title"":""Differential expression of two P5CS genes controlling proline accumulation during salt-stress requires ABA and is regulated by ABA1, ABI1 and AXR2 in Arabidopsis."",""doi"":""10.1046/j.1365-313x.1997.00557.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9351242/"",""year"":""1997"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Strizhov N; Abrahám E; Okrész L; Blickling S; Zilberstein A; Schell J; Koncz C; Szabados L"",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9448270"",""title"":""Mutational analysis of protein phosphatase 2C involved in abscisic acid signal transduction in higher plants."",""doi"":""10.1073/pnas.95.3.975"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9448270/"",""year"":""1998"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Sheen J."",""matched_aliases"":[""ABI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA07G106970	TkA07G106970	TkA07G106970.1	TK1151	3	O04719	P2C77_ARATH	Swiss-Prot		sp|O04719|P2C77_ARATH Protein phosphatase 2C 77	Arabidopsis thaliana	ABI2	48.0	321	80.106	3.39e-87	273.0	Medium	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At5g57050	脱落酸（ABA）信号通路抑制子，调控多种 ABA 响应，如气孔关闭、质膜渗透水流性（Pos）、高光胁迫、对葡萄糖的反应、种子萌发及营养生长抑制。	Repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), high light stress, response to glucose, seed germination and inhibition of vegetative growth.	"[{""pmid"":""10488243"",""title"":""Arabidopsis abi1-1 and abi2-1 phosphatase mutations reduce abscisic acid-induced cytoplasmic calcium rises in guard cells."",""doi"":""10.1105/tpc.11.9.1785"",""url"":""https://pubmed.ncbi.nlm.nih.gov/10488243/"",""year"":""1999"",""journal"":""The Plant cell"",""authors"":""Allen GJ; Kuchitsu K; Chu SP; Murata Y; Schroeder JI"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""10872217"",""title"":""The genes ABI1 and ABI2 are involved in abscisic acid- and drought-inducible expression of the Daucus carota L. Dc3 promoter in guard cells of transgenic Arabidopsis thaliana (L.) Heynh."",""doi"":""10.1007/s004250050692"",""url"":""https://pubmed.ncbi.nlm.nih.gov/10872217/"",""year"":""2000"",""journal"":""Planta"",""authors"":""Chak RK; Thomas TL; Quatrano RS; Rock CD"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""10950871"",""title"":""Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar."",""doi"":"""",""url"":""https://pubmed.ncbi.nlm.nih.gov/10950871/"",""year"":""2000"",""journal"":""Genes & development"",""authors"":""Arenas-Huertero F; Arroyo A; Zhou L; Sheen J; León P"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""11208021"",""title"":""The ABI1 and ABI2 protein phosphatases 2C act in a negative feedback regulatory loop of the abscisic acid signalling pathway."",""doi"":""10.1046/j.1365-313x.2001.00965.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11208021/"",""year"":""2001"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Merlot S; Gosti F; Guerrier D; Vavasseur A; Giraudat J"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""11701885"",""title"":""Abscisic acid activation of plasma membrane Ca(2+) channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in abi1-1 and abi2-1 protein phosphatase 2C mutants."",""doi"":""10.1105/tpc.010210"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11701885/"",""year"":""2001"",""journal"":""The Plant cell"",""authors"":""Murata Y; Pei ZM; Mori IC; Schroeder J"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""11707572"",""title"":""The role of ABA and the transpiration stream in the regulation of the osmotic water permeability of leaf cells."",""doi"":""10.1073/pnas.231471998"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11707572/"",""year"":""2001"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Morillon R; Chrispeels MJ"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""12119381"",""title"":""Hypersensitivity of abscisic acid-induced cytosolic calcium increases in the Arabidopsis farnesyltransferase mutant era1-2."",""doi"":""10.1105/tpc.010448"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12119381/"",""year"":""2002"",""journal"":""The Plant cell"",""authors"":""Allen GJ; Murata Y; Chu SP; Nafisi M; Schroeder JI"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""12194854"",""title"":""A calcium sensor and its interacting protein kinase are global regulators of abscisic acid signaling in Arabidopsis."",""doi"":""10.1016/s1534-5807(02)00229-0"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12194854/"",""year"":""2002"",""journal"":""Developmental cell"",""authors"":""Guo Y, Xiong L, Song CP, Gong D, Halfter U, Zhu JK."",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; 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Yu H; Bao Z; Guo X; Peng J; Yao Z; Chen G; Qu S; Dong H"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""15923322"",""title"":""Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance."",""doi"":""10.1104/pp.105.062257"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15923322/"",""year"":""2005"",""journal"":""Plant physiology"",""authors"":""Larkindale J; Hall JD; Knight MR; Vierling E"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""16339784"",""title"":""Role of abscisic acid (ABA) and Arabidopsis thaliana ABA-insensitive loci in low water potential-induced ABA and proline accumulation."",""doi"":""10.1093/jxb/erj026"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16339784/"",""year"":""2006"",""journal"":""Journal of experimental botany"",""authors"":""Verslues PE; Bray EA"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""16571665"",""title"":""Fibrillin expression is regulated by abscisic acid response regulators and is involved in abscisic acid-mediated photoprotection."",""doi"":""10.1073/pnas.0501720103"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16571665/"",""year"":""2006"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Yang Y, Sulpice R, Himmelbach A, Meinhard M, Christmann A, Grill E."",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""18278579"",""title"":""Interaction between sugar and abscisic acid signalling during early seedling development in Arabidopsis."",""doi"":""10.1007/s11103-008-9308-6"",""url"":""https://pubmed.ncbi.nlm.nih.gov/18278579/"",""year"":""2008"",""journal"":""Plant molecular biology"",""authors"":""Dekkers BJ; Schuurmans JA; Smeekens SC"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""22730405"",""title"":""A plasma membrane receptor kinase, GHR1, mediates abscisic acid- and hydrogen peroxide-regulated stomatal movement in Arabidopsis."",""doi"":""10.1105/tpc.112.100107"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22730405/"",""year"":""2012"",""journal"":""The Plant cell"",""authors"":""Hua D, Wang C, He J, Liao H, Duan Y, Zhu Z, Guo Y, Chen Z, Gong Z."",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""8787023"",""title"":""Abscisic acid induces the alcohol dehydrogenase gene in Arabidopsis."",""doi"":""10.1104/pp.111.2.381"",""url"":""https://pubmed.ncbi.nlm.nih.gov/8787023/"",""year"":""1996"",""journal"":""Plant physiology"",""authors"":""de Bruxelles GL; Peacock WJ; Dennis ES; Dolferus R"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9090884"",""title"":""Differential abscisic acid regulation of guard cell slow anion channels in Arabidopsis wild-type and abi1 and abi2 mutants."",""doi"":""10.1105/tpc.9.3.409"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9090884/"",""year"":""1997"",""journal"":""The Plant cell"",""authors"":""Pei ZM; Kuchitsu K; Ward JM; Schwarz M; Schroeder JI"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9108297"",""title"":""Abscisic acid-independent and abscisic acid-dependent regulation of proline biosynthesis following cold and osmotic stresses in Arabidopsis thaliana."",""doi"":""10.1007/s004380050397"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9108297/"",""year"":""1997"",""journal"":""Molecular & general genetics : MGG"",""authors"":""Savouré A; Hua XJ; Bertauche N; Van Montagu M; Verbruggen N"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9165752"",""title"":""The Arabidopsis ABSCISIC ACID-INSENSITIVE2 (ABI2) and ABI1 genes encode homologous protein phosphatases 2C involved in abscisic acid signal transduction."",""doi"":""10.1105/tpc.9.5.759"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9165752/"",""year"":""1997"",""journal"":""The Plant cell"",""authors"":""Leung J; Merlot S; Giraudat J"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9276963"",""title"":""Convergence of the abscisic acid, CO2, and extracellular calcium signal transduction pathways in stomatal guard cells."",""doi"":""10.1104/pp.114.4.1557"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9276963/"",""year"":""1997"",""journal"":""Plant physiology"",""authors"":""Webb AA; Hetherington AM"",""matched_aliases"":[""ABI2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
TkA07G106970	TkA07G106970	TkA07G106970.1	TK1151	5	Q9CAJ0	P2C16_ARATH	Swiss-Prot		sp|Q9CAJ0|P2C16_ARATH Protein phosphatase 2C 16	Arabidopsis thaliana	HAB1	47.8	318	76.658	1.72e-84	268.0	Medium	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At1g72770	脱落酸（ABA）信号通路的关键组成部分和抑制因子，调节多种ABA反应，如气孔关闭、种子萌发和营养生长抑制。	Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth.	"[{""pmid"":""14731256"",""title"":""Gain-of-function and loss-of-function phenotypes of the protein phosphatase 2C HAB1 reveal its role as a negative regulator of abscisic acid signalling."",""doi"":""10.1046/j.1365-313x.2003.01966.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/14731256/"",""year"":""2004"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Saez A; Apostolova N; Gonzalez-Guzman M; Gonzalez-Garcia MP; Nicolas C; Lorenzo O; Rodriguez PL"",""matched_aliases"":[""HAB1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""16798945"",""title"":""Enhancement of abscisic acid sensitivity and reduction of water consumption in Arabidopsis by combined inactivation of the protein phosphatases type 2C ABI1 and HAB1."",""doi"":""10.1104/pp.106.081018"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16798945/"",""year"":""2006"",""journal"":""Plant physiology"",""authors"":""Saez A; Robert N; Maktabi MH; Schroeder JI; Serrano R; Rodriguez PL"",""matched_aliases"":[""HAB1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""16876791"",""title"":""A hypermorphic mutation in the protein phosphatase 2C HAB1 strongly affects ABA signaling in Arabidopsis."",""doi"":""10.1016/j.febslet.2006.07.047"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16876791/"",""year"":""2006"",""journal"":""FEBS letters"",""authors"":""Robert N; Merlot S; N'guyen V; Boisson-Dernier A; Schroeder JI"",""matched_aliases"":[""HAB1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
TkA07G106970	TkA07G106970	TkA07G106970.1	TK1151	1	Q0JLP9	P2C06_ORYSJ	Swiss-Prot		sp|Q0JLP9|P2C06_ORYSJ Probable protein phosphatase 2C 6	Oryza sativa subsp. japonica	PP2C06	50.6	316	77.454	1.72e-92	288.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	Os01g0583100	可能的蛋白磷酸酶，可能在脱落酸（ABA）信号中发挥作用。	Probable protein phosphatase that may function in abscisic acid (ABA) signaling.	[]
TkA07G106970	TkA07G106970	TkA07G106970.1	TK1151	4	Q6L4R7	P2C53_ORYSJ	Swiss-Prot		sp|Q6L4R7|P2C53_ORYSJ Protein phosphatase 2C 53	Oryza sativa subsp. japonica	PP2C53	47.2	320	77.454	3.99e-85	268.0	Medium	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	Os05g0592800	蛋白磷酸酶，作为脱落酸(ABA)信号的负调控因子。	Protein phosphatase that acts as a negative regulator of abscisic acid (ABA) signaling.	"[{""pmid"":""26491145"",""title"":""ABA Regulates Subcellular Redistribution of OsABI-LIKE2, a Negative Regulator in ABA Signaling, to Control Root Architecture and Drought Resistance in Oryza sativa."",""doi"":""10.1093/pcp/pcv154"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26491145/"",""year"":""2015"",""journal"":""Plant & cell physiology"",""authors"":""Li C, Shen H, Wang T, Wang X."",""matched_aliases"":[""OsABIL2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"