query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
TkA05G000640	TkA05G000640	TkA05G000640.2	TK1151	6	Q9SY14	OSC17_ARATH	Swiss-Prot		sp|Q9SY14|OSC17_ARATH Hyperosmolality-gated Ca2+ permeable channel 1.7	Arabidopsis thaliana	OSCA1.7	69.4	745	97.258	0.0	1032.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At4g02900	参与植物气孔免疫的钙可渗透通道。	Calcium-permeable channel involved in plant stomatal immunity.	[]
TkA05G000640	TkA05G000640	TkA05G000640.2	TK1151	7	Q9LVE4	OSC15_ARATH	Swiss-Prot		sp|Q9LVE4|OSC15_ARATH Hyperosmolality-gated Ca2+ permeable channel 1.5	Arabidopsis thaliana	OSCA1.5	65.9	751	97.389	0.0	983.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At3g21620	作为一种渗透敏感的钙可通透阳离子通道。	Acts as an osmosensitive calcium-permeable cation channel.	[]
TkA05G000640	TkA05G000640	TkA05G000640.2	TK1151	8	Q5XEZ5	OSC12_ARATH	Swiss-Prot		sp|Q5XEZ5|OSC12_ARATH Hyperosmolality-gated Ca2+ permeable channel 1.2	Arabidopsis thaliana	OSCA1.2	65.0	751	97.65	0.0	962.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At4g22120	作为渗透敏感的钙渗透性阳离子通道。	Acts as an osmosensitive calcium-permeable cation channel.	"[{""pmid"":""30382938"",""title"":""OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels."",""doi"":""10.7554/elife.41844"",""url"":""https://pubmed.ncbi.nlm.nih.gov/30382938/"",""year"":""2018"",""journal"":""eLife"",""authors"":""Murthy SE, Dubin AE, Whitwam T, Jojoa-Cruz S, Cahalan SM, Mousavi SAR, Ward AB, Patapoutian A."",""matched_aliases"":[""OSCA1.2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""38592763"",""title"":""Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli."",""doi"":""10.7554/elife.93147"",""url"":""https://pubmed.ncbi.nlm.nih.gov/38592763/"",""year"":""2024"",""journal"":""eLife"",""authors"":""Jojoa-Cruz S, Dubin AE, Lee WH, Ward AB."",""matched_aliases"":[""OSCA1.2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA05G000640	TkA05G000640	TkA05G000640.2	TK1151	9	Q9XEA1	OSC11_ARATH	Swiss-Prot		sp|Q9XEA1|OSC11_ARATH Hyperosmolality-gated Ca2+ permeable channel 1.1	Arabidopsis thaliana	OSCA1	64.8	756	98.303	0.0	960.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At4g04340	可能作为高渗透压门控的非选择性阳离子通道，允许 Ca²⁺ 通过。	May act as a hyperosmolarity-gated nonselective cation channel permeable to Ca²⁺.	"[{""pmid"":""25162526"",""title"":""OSCA1 mediates osmotic-stress-evoked Ca2+ increases vital for osmosensing in Arabidopsis."",""doi"":""10.1038/nature13593"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25162526/"",""year"":""2014"",""journal"":""Nature"",""authors"":""Yuan F, Yang H, Xue Y, Kong D, Ye R, Li C, Zhang J, Theprungsirikul L, Shrift T, Krichilsky B, Johnson DM, Swift GB, He Y, Siedow JN, Pei ZM."",""matched_aliases"":[""OSCA1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""30382938"",""title"":""OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels."",""doi"":""10.7554/elife.41844"",""url"":""https://pubmed.ncbi.nlm.nih.gov/30382938/"",""year"":""2018"",""journal"":""eLife"",""authors"":""Murthy SE, Dubin AE, Whitwam T, Jojoa-Cruz S, Cahalan SM, Mousavi SAR, Ward AB, Patapoutian A."",""matched_aliases"":[""OSCA1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA05G000640	TkA05G000640	TkA05G000640.2	TK1151	10	B5TYT3	OSC13_ARATH	Swiss-Prot		sp|B5TYT3|OSC13_ARATH Hyperosmolality-gated Ca2+ permeable channel 1.3	Arabidopsis thaliana	OSCA1.3	64.9	753	97.258	0.0	958.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At1g11960	在植物气孔免疫中起关键作用的钙渗透通道。	Calcium-permeable channel that plays a key role in plant stomatal immunity.	"[{""pmid"":""32846426"",""title"":""The calcium-permeable channel OSCA1.3 regulates plant stomatal immunity."",""doi"":""10.1038/s41586-020-2702-1"",""url"":""https://pubmed.ncbi.nlm.nih.gov/32846426/"",""year"":""2020"",""journal"":""Nature"",""authors"":""Thor K, Jiang S, Michard E, George J, Scherzer S, Huang S, Dindas J, Derbyshire P, Leitão N, DeFalco TA, Köster P, Hunter K, Kimura S, Gronnier J, Stransfeld L, Kadota Y, Bücherl CA, Charpentier M, Wrzaczek M, MacLean D, Oldroyd GED, Menke FLH, Roelfsema MRG, Hedrich R, Feijó J, Zipfel C."",""matched_aliases"":[""OSCA1.3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"