query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
TkA02G075560	TkA02G075560	TkA02G075560.1	TK1151	1	Q9M4A2	SPO11_ARATH	Swiss-Prot		sp|Q9M4A2|SPO11_ARATH Meiotic recombination protein SPO11-1	Arabidopsis thaliana	SPO11-1	66.5	355	96.467	1.22e-179	505.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At3g13170	DNA核酸内切酶，特异性介导DNA切割，形成启动减数分裂重组的双链断裂（DSB）。	DNA endonuclease, which specifically mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.	"[{""pmid"":""11157765"",""title"":""AtSPO11-1 is necessary for efficient meiotic recombination in plants."",""doi"":""10.1093/emboj/20.3.589"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11157765/"",""year"":""2001"",""journal"":""The EMBO journal"",""authors"":""Grelon M; Vezon D; Gendrot G; Pelletier G"",""matched_aliases"":[""AtSPO11-1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""17018031"",""title"":""Arabidopsis SPO11-2 functions with SPO11-1 in meiotic recombination."",""doi"":""10.1111/j.1365-313x.2006.02867.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17018031/"",""year"":""2006"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Stacey NJ, Kuromori T, Azumi Y, Roberts G, Breuer C, Wada T, Maxwell A, Roberts K, Sugimoto-Shirasu K."",""matched_aliases"":[""AtSPO11-1"",""SPO11-1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""17965269"",""title"":""The catalytically active tyrosine residues of both SPO11-1 and SPO11-2 are required for meiotic double-strand break induction in Arabidopsis."",""doi"":""10.1105/tpc.107.054817"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17965269/"",""year"":""2007"",""journal"":""The Plant cell"",""authors"":""Hartung F, Wurz-Wildersinn R, Fuchs J, Schubert I, Suer S, Puchta H."",""matched_aliases"":[""SPO11-1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""19763177"",""title"":""A high throughput genetic screen identifies new early meiotic recombination functions in Arabidopsis thaliana."",""doi"":""10.1371/journal.pgen.1000654"",""url"":""https://pubmed.ncbi.nlm.nih.gov/19763177/"",""year"":""2009"",""journal"":""PLoS genetics"",""authors"":""De Muyt A, Pereira L, Vezon D, Chelysheva L, Gendrot G, Chambon A, Lainé-Choinard S, Pelletier G, Mercier R, Nogué F, Grelon M."",""matched_aliases"":[""AtSPO11-1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""26917763"",""title"":""A DNA topoisomerase VI-like complex initiates meiotic recombination."",""doi"":""10.1126/science.aad5196"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26917763/"",""year"":""2016"",""journal"":""Science (New York, N.Y.)"",""authors"":""Vrielynck N, Chambon A, Vezon D, Pereira L, Chelysheva L, De Muyt A, Mézard C, Mayer C, Grelon M."",""matched_aliases"":[""SPO11-1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA02G075560	TkA02G075560	TkA02G075560.1	TK1151	5	Q9LZ03	TOP6A_ARATH	Swiss-Prot		sp|Q9LZ03|TOP6A_ARATH DNA topoisomerase 6 subunit A	Arabidopsis thaliana	TOP6A	41.3	283	76.902	2.51e-72	234.0	Medium	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At5g02820	DNA 拓扑异构酶 VI 的组成部分，参与染色质组织和内复制循环的推进。	Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles.	"[{""pmid"":""12119417"",""title"":""A crucial role for the putative Arabidopsis topoisomerase VI in plant growth and development."",""doi"":""10.1073/pnas.152337599"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12119417/"",""year"":""2002"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Yin Y; Cheong H; Friedrichsen D; Zhao Y; Hu J; Mora-Garcia S; Chory J"",""matched_aliases"":[""AtSPO11-3"",""BIN5""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""12401175"",""title"":""DNA topoisomerase VI is essential for endoreduplication in Arabidopsis."",""doi"":""10.1016/s0960-9822(02)01198-3"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12401175/"",""year"":""2002"",""journal"":""Current biology : CB"",""authors"":""Sugimoto-Shirasu K; Stacey NJ; Corsar J; Roberts K; McCann MC"",""matched_aliases"":[""AtSPO11-3"",""RHL2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
TkA02G075560	TkA02G075560	TkA02G075560.1	TK1151	2	Q5ZPV8	SPO11_ORYSI	Swiss-Prot		sp|Q5ZPV8|SPO11_ORYSI Meiotic recombination protein SPO11-1	Oryza sativa subsp. indica	SPO11-1	63.3	349	93.478	2.33e-165	470.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)		DNA核酸内切酶，特异性介导DNA切割，形成启动减数分裂重组的双链断裂（DSB）。	DNA endonuclease, which specifically mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.	[]
TkA02G075560	TkA02G075560	TkA02G075560.1	TK1151	3	Q7Y021	SPO11_ORYSJ	Swiss-Prot		sp|Q7Y021|SPO11_ORYSJ Meiotic recombination protein SPO11-1	Oryza sativa subsp. japonica	SPO11-1	63.3	349	93.478	2.33e-165	470.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	Os03g0752200	DNA核酸内切酶，特异性介导DNA切割，形成启动减数分裂重组的双链断裂（DSB）。	DNA endonuclease, which specifically mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.	"[{""pmid"":""20625906"",""title"":""OsSPO11-1 is essential for both homologous chromosome pairing and crossover formation in rice."",""doi"":""10.1007/s00412-010-0284-7"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20625906/"",""year"":""2010"",""journal"":""Chromosoma"",""authors"":""Yu H; Wang M; Tang D; Wang K; Chen F; Gong Z; Gu M; Cheng Z"",""matched_aliases"":[""OsSPO11-1"",""SPO11-1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"