query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_038559	gene-LXL04_038559	KAL4555925.1	OH-1004	1	Q9M0Z3	KEA3_ARATH	Swiss-Prot		K(+) efflux antiporter 3, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=KEA3 PE=1 SV=2	Arabidopsis thaliana	KEA3	71.314	746	94.885	0.0	980.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g04850	可能作为电中性 K⁺/H⁺ 反向转运蛋白，介导质子从类囊体腔向叶绿体基质的外流。	May act as an electroneutral K⁺/H⁺ antiporter mediating proton efflux from the thylakoid lumen to the chloroplast stroma.	"[{""pmid"":""24278440"",""title"":""A novel AtKEA gene family, homolog of bacterial K+/H+ antiporters, plays potential roles in K+ homeostasis and osmotic adjustment in Arabidopsis."",""doi"":""10.1371/journal.pone.0081463"",""url"":""https://pubmed.ncbi.nlm.nih.gov/24278440/"",""year"":""2013"",""journal"":""PloS one"",""authors"":""Zheng S, Pan T, Fan L, Qiu QS."",""matched_aliases"":[""AtKEA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""25451040"",""title"":""Ion antiport accelerates photosynthetic acclimation in fluctuating light environments."",""doi"":""10.1038/ncomms6439"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25451040/"",""year"":""2014"",""journal"":""Nature communications"",""authors"":""Armbruster U, Carrillo LR, Venema K, Venema K, Pavlovic L, Schmidtmann E, Kornfeld A, Jahns P, Berry JA, Kramer DM, Jonikas MC."",""matched_aliases"":[""KEA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""27335350"",""title"":""Regulation and Levels of the Thylakoid K+/H+ Antiporter KEA3 Shape the Dynamic Response of Photosynthesis in Fluctuating Light."",""doi"":""10.1093/pcp/pcw085"",""url"":""https://pubmed.ncbi.nlm.nih.gov/27335350/"",""year"":""2016"",""journal"":""Plant & cell physiology"",""authors"":""Armbruster U, Leonelli L, Correa Galvis V, Strand D, Quinn EH, Jonikas MC, Niyogi KK."",""matched_aliases"":[""KEA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""27528686"",""title"":""Rapid hyperosmotic-induced Ca2+ responses in Arabidopsis thaliana exhibit sensory potentiation and involvement of plastidial KEA transporters."",""doi"":""10.1073/pnas.1519555113"",""url"":""https://pubmed.ncbi.nlm.nih.gov/27528686/"",""year"":""2016"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Stephan AB, Kunz HH, Yang E, Schroeder JI."",""matched_aliases"":[""KEA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""31053658"",""title"":""Photosynthesis in Arabidopsis Is Unaffected by the Function of the Vacuolar K +  Channel TPK3."",""doi"":""10.1104/pp.19.00255"",""url"":""https://pubmed.ncbi.nlm.nih.gov/31053658/"",""year"":""2019"",""journal"":""Plant physiology"",""authors"":""Höhner R, Galvis VC, Strand DD, Völkner C, Krämer M, Messer M, Dinc F, Sjuts I, Bölter B, Kramer DM, Armbruster U, Kunz HH."",""matched_aliases"":[""KEA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""31201341"",""title"":""K +  and Cl -  channels/transporters independently fine-tune photosynthesis in plants."",""doi"":""10.1038/s41598-019-44972-z"",""url"":""https://pubmed.ncbi.nlm.nih.gov/31201341/"",""year"":""2019"",""journal"":""Scientific reports"",""authors"":""Dukic E, Herdean A, Cheregi O, Sharma A, Nziengui H, Dmitruk D, Solymosi K, Pribil M, Spetea C."",""matched_aliases"":[""KEA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""31296940"",""title"":""Evidence for potassium transport activity of Arabidopsis KEA1-KEA6."",""doi"":""10.1038/s41598-019-46463-7"",""url"":""https://pubmed.ncbi.nlm.nih.gov/31296940/"",""year"":""2019"",""journal"":""Scientific reports"",""authors"":""Tsujii M, Kera K, Hamamoto S, Kuromori T, Shikanai T, Uozumi N."",""matched_aliases"":[""DPGR"",""KEA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""31427465"",""title"":""Modification of Activity of the Thylakoid H + /K +  Antiporter KEA3 Disturbs ∆pH-Dependent Regulation of Photosynthesis."",""doi"":""10.1104/pp.19.00766"",""url"":""https://pubmed.ncbi.nlm.nih.gov/31427465/"",""year"":""2019"",""journal"":""Plant physiology"",""authors"":""Wang C, Shikanai T."",""matched_aliases"":[""DPGR"",""KEA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""32041909"",""title"":""H +  Transport by K +  EXCHANGE ANTIPORTER3 Promotes Photosynthesis and Growth in Chloroplast ATP Synthase Mutants."",""doi"":""10.1104/pp.19.01561"",""url"":""https://pubmed.ncbi.nlm.nih.gov/32041909/"",""year"":""2020"",""journal"":""Plant physiology"",""authors"":""Correa Galvis V, Strand DD, Messer M, Thiele W, Bethmann S, Hübner D, Uflewski M, Kaiser E, Siemiatkowska B, Morris BA, Tóth SZ, Watanabe M, Brückner F, Höfgen R, Jahns P, Schöttler MA, Armbruster U."",""matched_aliases"":[""KEA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""32978277"",""title"":""Collaboration between NDH and KEA3 Allows Maximally Efficient Photosynthesis after a Long Dark Adaptation."",""doi"":""10.1104/pp.20.01069"",""url"":""https://pubmed.ncbi.nlm.nih.gov/32978277/"",""year"":""2020"",""journal"":""Plant physiology"",""authors"":""Basso L, Yamori W, Szabo I, Shikanai T."",""matched_aliases"":[""KEA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_038559	gene-LXL04_038559	KAL4555925.1	OH-1004	2	O65272	KEA2_ARATH	Swiss-Prot		K(+) efflux antiporter 2, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=KEA2 PE=1 SV=2	Arabidopsis thaliana	KEA2	37.523	549	69.182	1.21e-84	295.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g00630	可能作为电中性 K⁺/H⁺ 反向转运蛋白，调节质体中的单价阳离子及 pH 稳态。	May act as an electroneutral K⁺/H⁺ antiporter regulating monovalent-cation and pH homeostasis in plastids.	"[{""pmid"":""22551943"",""title"":""Arabidopsis KEA2, a homolog of bacterial KefC, encodes a K(+)/H(+) antiporter with a chloroplast transit peptide."",""doi"":""10.1016/j.bbamem.2012.04.011"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22551943/"",""year"":""2012"",""journal"":""Biochimica et biophysica acta"",""authors"":""Aranda-Sicilia MN, Cagnac O, Chanroj S, Sze H, Rodríguez-Rosales MP, Venema K, Venema K."",""matched_aliases"":[""AtKEA2"",""KEA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""24278440"",""title"":""A novel AtKEA gene family, homolog of bacterial K+/H+ antiporters, plays potential roles in K+ homeostasis and osmotic adjustment in Arabidopsis."",""doi"":""10.1371/journal.pone.0081463"",""url"":""https://pubmed.ncbi.nlm.nih.gov/24278440/"",""year"":""2013"",""journal"":""PloS one"",""authors"":""Zheng S, Pan T, Fan L, Qiu QS."",""matched_aliases"":[""AtKEA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""27443603"",""title"":""Envelope K+/H+ Antiporters AtKEA1 and AtKEA2 Function in Plastid Development."",""doi"":""10.1104/pp.16.00995"",""url"":""https://pubmed.ncbi.nlm.nih.gov/27443603/"",""year"":""2016"",""journal"":""Plant physiology"",""authors"":""Aranda-Sicilia MN, Aboukila A, Armbruster U, Cagnac O, Schumann T, Kunz HH, Jahns P, Rodríguez-Rosales MP, Sze H, Venema K, Venema K."",""matched_aliases"":[""AtKEA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""33111995"",""title"":""Plastidial transporters KEA1 and KEA2 at the inner envelope membrane adjust stromal pH in the dark."",""doi"":""10.1111/nph.17042"",""url"":""https://pubmed.ncbi.nlm.nih.gov/33111995/"",""year"":""2021"",""journal"":""The New phytologist"",""authors"":""Aranda Sicilia MN, Sánchez Romero ME, Rodríguez Rosales MP, Venema K, Venema K."",""matched_aliases"":[""AtKEA2"",""KEA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""33485149"",""title"":""Loss of function of the chloroplast membrane K + /H +  antiporters AtKEA1 and AtKEA2 alters the ROS and NO metabolism but promotes drought stress resilience."",""doi"":""10.1016/j.plaphy.2021.01.010"",""url"":""https://pubmed.ncbi.nlm.nih.gov/33485149/"",""year"":""2021"",""journal"":""Plant physiology and biochemistry : PPB"",""authors"":""Sánchez-McSweeney A, González-Gordo S, Aranda-Sicilia MN, Rodríguez-Rosales MP, Venema K, Venema K, Palma JM, Corpas FJ."",""matched_aliases"":[""AtKEA2"",""KEA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""34235544"",""title"":""Loss of inner-envelope K+/H+ exchangers impairs plastid rRNA maturation and gene expression."",""doi"":""10.1093/plcell/koab123"",""url"":""https://pubmed.ncbi.nlm.nih.gov/34235544/"",""year"":""2021"",""journal"":""The Plant cell"",""authors"":""DeTar RA, Barahimipour R, Manavski N, Schwenkert S, Höhner R, Bölter B, Inaba T, Meurer J, Zoschke R, Kunz HH."",""matched_aliases"":[""KEA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""35193734"",""title"":""Exogenous sucrose influences KEA1 and KEA2 to regulate abscisic acid-mediated primary root growth in Arabidopsis."",""doi"":""10.1016/j.plantsci.2022.111209"",""url"":""https://pubmed.ncbi.nlm.nih.gov/35193734/"",""year"":""2022"",""journal"":""Plant science : an international journal of experimental plant biology"",""authors"":""Zheng S, Su M, Shi Z, Gao H, Ma C, Zhu S, Zhang L, Wu G, Wu W, Wang J, Zhang J, Zhang T."",""matched_aliases"":[""KEA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_038559	gene-LXL04_038559	KAL4555925.1	OH-1004	3	Q9ZTZ7	KEA1_ARATH	Swiss-Prot		K(+) efflux antiporter 1, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=KEA1 PE=1 SV=2	Arabidopsis thaliana	KEA1	36.918	558	70.332	1.24e-84	295.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At1g01790	可能作为电中性 K⁺/H⁺ 反向转运蛋白，参与叶绿体 K⁺ 稳态、渗透调节及质体发育。	May act as an electroneutral K⁺/H⁺ antiporter in chloroplast K⁺ homeostasis, osmotic adjustment and plastid development.	"[{""pmid"":""24278440"",""title"":""A novel AtKEA gene family, homolog of bacterial K+/H+ antiporters, plays potential roles in K+ homeostasis and osmotic adjustment in Arabidopsis."",""doi"":""10.1371/journal.pone.0081463"",""url"":""https://pubmed.ncbi.nlm.nih.gov/24278440/"",""year"":""2013"",""journal"":""PloS one"",""authors"":""Zheng S, Pan T, Fan L, Qiu QS."",""matched_aliases"":[""AtKEA1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""27443603"",""title"":""Envelope K+/H+ Antiporters AtKEA1 and AtKEA2 Function in Plastid Development."",""doi"":""10.1104/pp.16.00995"",""url"":""https://pubmed.ncbi.nlm.nih.gov/27443603/"",""year"":""2016"",""journal"":""Plant physiology"",""authors"":""Aranda-Sicilia MN, Aboukila A, Armbruster U, Cagnac O, Schumann T, Kunz HH, Jahns P, Rodríguez-Rosales MP, Sze H, Venema K, Venema K."",""matched_aliases"":[""AtKEA1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""31296940"",""title"":""Evidence for potassium transport activity of Arabidopsis KEA1-KEA6."",""doi"":""10.1038/s41598-019-46463-7"",""url"":""https://pubmed.ncbi.nlm.nih.gov/31296940/"",""year"":""2019"",""journal"":""Scientific reports"",""authors"":""Tsujii M, Kera K, Hamamoto S, Kuromori T, Shikanai T, Uozumi N."",""matched_aliases"":[""KEA1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""33111995"",""title"":""Plastidial transporters KEA1 and KEA2 at the inner envelope membrane adjust stromal pH in the dark."",""doi"":""10.1111/nph.17042"",""url"":""https://pubmed.ncbi.nlm.nih.gov/33111995/"",""year"":""2021"",""journal"":""The New phytologist"",""authors"":""Aranda Sicilia MN, Sánchez Romero ME, Rodríguez Rosales MP, Venema K, Venema K."",""matched_aliases"":[""AtKEA1"",""KEA1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""33485149"",""title"":""Loss of function of the chloroplast membrane K + /H +  antiporters AtKEA1 and AtKEA2 alters the ROS and NO metabolism but promotes drought stress resilience."",""doi"":""10.1016/j.plaphy.2021.01.010"",""url"":""https://pubmed.ncbi.nlm.nih.gov/33485149/"",""year"":""2021"",""journal"":""Plant physiology and biochemistry : PPB"",""authors"":""Sánchez-McSweeney A, González-Gordo S, Aranda-Sicilia MN, Rodríguez-Rosales MP, Venema K, Venema K, Palma JM, Corpas FJ."",""matched_aliases"":[""AtKEA1"",""KEA1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""34235544"",""title"":""Loss of inner-envelope K+/H+ exchangers impairs plastid rRNA maturation and gene expression."",""doi"":""10.1093/plcell/koab123"",""url"":""https://pubmed.ncbi.nlm.nih.gov/34235544/"",""year"":""2021"",""journal"":""The Plant cell"",""authors"":""DeTar RA, Barahimipour R, Manavski N, Schwenkert S, Höhner R, Bölter B, Inaba T, Meurer J, Zoschke R, Kunz HH."",""matched_aliases"":[""KEA1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""35193734"",""title"":""Exogenous sucrose influences KEA1 and KEA2 to regulate abscisic acid-mediated primary root growth in Arabidopsis."",""doi"":""10.1016/j.plantsci.2022.111209"",""url"":""https://pubmed.ncbi.nlm.nih.gov/35193734/"",""year"":""2022"",""journal"":""Plant science : an international journal of experimental plant biology"",""authors"":""Zheng S, Su M, Shi Z, Gao H, Ma C, Zhu S, Zhang L, Wu G, Wu W, Wang J, Zhang J, Zhang T."",""matched_aliases"":[""KEA1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"