query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_032673	gene-LXL04_032673	KAL4560521.1	OH-1004	3	Q9S814	EIN2_ARATH	Swiss-Prot		Ethylene-insensitive protein 2 OS=Arabidopsis thaliana OX=3702 GN=EIN2 PE=1 SV=1	Arabidopsis thaliana	EIN2	46.437	1305	99.007	0.0	1058.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At5g03280	受乙烯 调节的信号通路的核心因子，参与发育、植物防御、衰老、核苷酸糖通量和趋向性等多种过程。	Central factor in signaling pathways regulated by ethylene (ET) and involved in various processes including development, plant defense, senescence, nucleotide sugar flux, and tropisms.	"[{""pmid"":""10381874"",""title"":""EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis."",""doi"":""10.1126/science.284.5423.2148"",""url"":""https://pubmed.ncbi.nlm.nih.gov/10381874/"",""year"":""1999"",""journal"":""Science (New York, N.Y.)"",""authors"":""Alonso JM, Hirayama T, Roman G, Nourizadeh S, Ecker JR."",""matched_aliases"":[""EIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""12953109"",""title"":""Analysis of combinatorial loss-of-function mutants in the Arabidopsis ethylene receptors reveals that the ers1 etr1 double mutant has severe developmental defects that are EIN2 dependent."",""doi"":""10.1105/tpc.013060"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12953109/"",""year"":""2003"",""journal"":""The Plant cell"",""authors"":""Hall AE, Bleecker AB."",""matched_aliases"":[""EIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""14973160"",""title"":""Growth regulators and the control of nucleotide sugar flux."",""doi"":""10.1105/tpc.019661"",""url"":""https://pubmed.ncbi.nlm.nih.gov/14973160/"",""year"":""2004"",""journal"":""The Plant cell"",""authors"":""Seifert GJ, Barber C, Wells B, Roberts K."",""matched_aliases"":[""EIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""15010611"",""title"":""Transcriptome analysis of O3-exposed Arabidopsis reveals that multiple signal pathways act mutually antagonistically to induce gene expression."",""doi"":""10.1023/b:plan.0000019064.55734.52"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15010611/"",""year"":""2003"",""journal"":""Plant molecular biology"",""authors"":""Tamaoki M, Nakajima N, Kubo A, Aono M, Matsuyama T, Saji H."",""matched_aliases"":[""EIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""15272873"",""title"":""Transcriptional profiling by cDNA-AFLP and microarray analysis reveals novel insights into the early response to ethylene in Arabidopsis."",""doi"":""10.1111/j.1365-313x.2004.02156.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15272873/"",""year"":""2004"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""De Paepe A, Vuylsteke M, Van Hummelen P, Zabeau M, Van Der Straeten D."",""matched_aliases"":[""EIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""19196655"",""title"":""Interplay between ethylene, ETP1/ETP2 F-box proteins, and degradation of EIN2 triggers ethylene responses in Arabidopsis."",""doi"":""10.1101/gad.1765709"",""url"":""https://pubmed.ncbi.nlm.nih.gov/19196655/"",""year"":""2009"",""journal"":""Genes & development"",""authors"":""Qiao H, Chang KN, Yazaki J, Ecker JR."",""matched_aliases"":[""EIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""20647342"",""title"":""Ethylene-induced stabilization of ETHYLENE INSENSITIVE3 and EIN3-LIKE1 is mediated by proteasomal degradation of EIN3 binding F-box 1 and 2 that requires EIN2 in Arabidopsis."",""doi"":""10.1105/tpc.110.076588"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20647342/"",""year"":""2010"",""journal"":""The Plant cell"",""authors"":""An F, Zhao Q, Ji Y, Li W, Jiang Z, Yu X, Zhang C, Han Y, He W, Liu Y, Zhang S, Ecker JR, Guo H."",""matched_aliases"":[""EIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""21631530"",""title"":""EIN2 regulates salt stress response and interacts with a MA3 domain-containing protein ECIP1 in Arabidopsis."",""doi"":""10.1111/j.1365-3040.2011.02363.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/21631530/"",""year"":""2011"",""journal"":""Plant, cell & environment"",""authors"":""Lei G, Shen M, Li ZG, Zhang B, Duan KX, Wang N, Cao YR, Zhang WK, Ma B, Ling HQ, Chen SY, Zhang JS."",""matched_aliases"":[""EIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""26496607"",""title"":""EIN2-directed translational regulation of ethylene signaling in Arabidopsis."",""doi"":""10.1016/j.cell.2015.09.037"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26496607/"",""year"":""2015"",""journal"":""Cell"",""authors"":""Li W, Ma M, Feng Y, Li H, Wang Y, Ma Y, Li M, An F, Guo H."",""matched_aliases"":[""EIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""26507893"",""title"":""Mitogen-activated protein kinase 6 mediates nuclear translocation of ORE3 to promote ORE9 gene expression in methyl jasmonate-induced leaf senescence."",""doi"":""10.1093/jxb/erv438"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26507893/"",""year"":""2016"",""journal"":""Journal of experimental botany"",""authors"":""Zhang Y, Liu J, Chai J, Xing D."",""matched_aliases"":[""EIN2"",""ORE3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""7770519"",""title"":""Cytokinin action is coupled to ethylene in its effects on the inhibition of root and hypocotyl elongation in Arabidopsis thaliana seedlings."",""doi"":""10.1104/pp.107.4.1075"",""url"":""https://pubmed.ncbi.nlm.nih.gov/7770519/"",""year"":""1995"",""journal"":""Plant physiology"",""authors"":""Cary AJ, Liu W, Howell SH."",""matched_aliases"":[""CKR1"",""EIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""9351240"",""title"":""Identification of three genetic loci controlling leaf senescence in Arabidopsis thaliana."",""doi"":""10.1046/j.1365-313x.1997.00527.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9351240/"",""year"":""1997"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Oh SA, Park JH, Lee GI, Paek KH, Park SK, Nam HG."",""matched_aliases"":[""EIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_032673	gene-LXL04_032673	KAL4560521.1	OH-1004	4	Q0D8I9	EIN2_ORYSJ	Swiss-Prot		Protein ETHYLENE-INSENSITIVE 2 OS=Oryza sativa subsp. japonica OX=39947 GN=EIN2 PE=2 SV=1	Oryza sativa subsp. japonica	EIN2	38.103	1286	97.684	0.0	723.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os07g0155600	控制发育、衰老和籽粒大小的乙烯信号通路核心因子。	Central factor in ethylene signaling pathways that control development, senescence and grain size.	"[{""pmid"":""15047876"",""title"":""OsEIN2 is a positive component in ethylene signaling in rice."",""doi"":""10.1093/pcp/pch033"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15047876/"",""year"":""2004"",""journal"":""Plant & cell physiology"",""authors"":""Jun SH; Han MJ; Lee S; Seo YS; Kim WT; An G"",""matched_aliases"":[""EIN2"",""OsEIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""23718947"",""title"":""Identification of rice ethylene-response mutants and characterization of MHZ7/OsEIN2 in distinct ethylene response and yield trait regulation."",""doi"":""10.1093/mp/sst087"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23718947/"",""year"":""2013"",""journal"":""Molecular plant"",""authors"":""Ma B; He SJ; Duan KX; Yin CC; Chen H; Yang C; Xiong Q; Song QX; Lu X; Chen HW; Zhang WK; Lu TG; Chen SY; Zhang JS"",""matched_aliases"":[""EIN2"",""MHZ7"",""OsEIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
