query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_021933	gene-LXL04_021933	KAL4575092.1	OH-1004	1	Q06548	PBL9_ARATH	Swiss-Prot		Probable serine/threonine-protein kinase PBL9 OS=Arabidopsis thaliana OX=3702 GN=PBL9 PE=1 SV=1	Arabidopsis thaliana	PBL9	68.785	362	91.384	1.46e-179	508.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At1g07570	可能的双功能激酶。	Possible bi-functional kinase.	"[{""pmid"":""1450380"",""title"":""Novel protein kinase of Arabidopsis thaliana (APK1) that phosphorylates tyrosine, serine and threonine."",""doi"":""10.1007/bf00046450"",""url"":""https://pubmed.ncbi.nlm.nih.gov/1450380/"",""year"":""1992"",""journal"":""Plant molecular biology"",""authors"":""Hirayama T; Oka A"",""matched_aliases"":[""APK1A""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_021933	gene-LXL04_021933	KAL4575092.1	OH-1004	3	P46573	PBL10_ARATH	Swiss-Prot		Probable serine/threonine-protein kinase PBL10 OS=Arabidopsis thaliana OX=3702 GN=PBL10 PE=1 SV=2	Arabidopsis thaliana	PBL10	73.125	320	83.551	1.3e-177	503.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At2g28930	可能的双功能激酶。	Possible bi-functional kinase.	"[{""pmid"":""24828466"",""title"":""Light-induced stomatal opening is affected by the guard cell protein kinase APK1b."",""doi"":""10.1371/journal.pone.0097161"",""url"":""https://pubmed.ncbi.nlm.nih.gov/24828466/"",""year"":""2014"",""journal"":""PloS one"",""authors"":""Elhaddad NS; Hunt L; Sloan J; Gray JE"",""matched_aliases"":[""APK1B""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_021933	gene-LXL04_021933	KAL4575092.1	OH-1004	4	P43293	PBL11_ARATH	Swiss-Prot		Probable serine/threonine-protein kinase PBL11 OS=Arabidopsis thaliana OX=3702 GN=PBL11 PE=1 SV=2	Arabidopsis thaliana	PBL11	62.629	388	97.65	2.06e-177	501.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At5g02290	可能在植物生长和发育的调节中发挥作用（可能）。	May play a role in the regulation of plant growth and development (Probable).	[]
LXL04_021933	gene-LXL04_021933	KAL4575092.1	OH-1004	5	O48814	BIK1_ARATH	Swiss-Prot		Serine/threonine-protein kinase BIK1 OS=Arabidopsis thaliana OX=3702 GN=BIK1 PE=1 SV=1	Arabidopsis thaliana	BIK1	63.859	368	93.995	8.65e-168	477.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At2g39660	在免疫反应中起核心作用。	Plays a central role in immune responses.	"[{""pmid"":""16339855"",""title"":""The membrane-anchored BOTRYTIS-INDUCED KINASE1 plays distinct roles in Arabidopsis resistance to necrotrophic and biotrophic pathogens."",""doi"":""10.1105/tpc.105.035576"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16339855/"",""year"":""2006"",""journal"":""The Plant cell"",""authors"":""Veronese P; Nakagami H; Bluhm B; Abuqamar S; Chen X; Salmeron J; Dietrich RA; Hirt H; Mengiste T"",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""20404519"",""title"":""Phosphorylation of receptor-like cytoplasmic kinases by bacterial flagellin."",""doi"":""10.4161/psb.11500"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20404519/"",""year"":""2010"",""journal"":""Plant signaling & behavior"",""authors"":""Lu D; Wu S; He P; Shan L"",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""20413097"",""title"":""Receptor-like cytoplasmic kinases integrate signaling from multiple plant immune receptors and are targeted by a Pseudomonas syringae effector."",""doi"":""10.1016/j.chom.2010.03.007"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20413097/"",""year"":""2010"",""journal"":""Cell host & microbe"",""authors"":""Zhang J, Li W, Xiang T, Liu Z, Laluk K, Ding X, Zou Y, Gao M, Zhang X, Chen S, Mengiste T, Zhang Y, Zhou JM."",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22504181"",""title"":""A Xanthomonas uridine 5'-monophosphate transferase inhibits plant immune kinases."",""doi"":""10.1038/nature10962"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22504181/"",""year"":""2012"",""journal"":""Nature"",""authors"":""Feng F; Yang F; Rong W; Wu X; Zhang J; Chen S; He C; Zhou JM"",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""23431184"",""title"":""BIK1 interacts with PEPRs to mediate ethylene-induced immunity."",""doi"":""10.1073/pnas.1215543110"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23431184/"",""year"":""2013"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Liu Z; Wu Y; Yang F; Zhang Y; Chen S; Xie Q; Tian X; Zhou JM"",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""23818580"",""title"":""Inverse modulation of plant immune and brassinosteroid signaling pathways by the receptor-like cytoplasmic kinase BIK1."",""doi"":""10.1073/pnas.1302154110"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23818580/"",""year"":""2013"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Lin W; Lu D; Gao X; Jiang S; Ma X; Wang Z; Mengiste T; He P; Shan L"",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""24104392"",""title"":""Identification and functional analysis of phosphorylation residues of the Arabidopsis BOTRYTIS-INDUCED KINASE1."",""doi"":""10.1007/s13238-013-3053-6"",""url"":""https://pubmed.ncbi.nlm.nih.gov/24104392/"",""year"":""2013"",""journal"":""Protein & cell"",""authors"":""Xu J; Wei X; Yan L; Liu D; Ma Y; Guo Y; Peng C; Zhou H; Yang C; Lou Z; Shui W"",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""24629339"",""title"":""The FLS2-associated kinase BIK1 directly phosphorylates the NADPH oxidase RbohD to control plant immunity."",""doi"":""10.1016/j.chom.2014.02.009"",""url"":""https://pubmed.ncbi.nlm.nih.gov/24629339/"",""year"":""2014"",""journal"":""Cell host & microbe"",""authors"":""Li L; Li M; Yu L; Zhou Z; Liang X; Liu Z; Cai G; Gao L; Zhang X; Wang Y; Chen S; Zhou JM"",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""25522736"",""title"":""Microbe-associated molecular pattern-induced calcium signaling requires the receptor-like cytoplasmic kinases, PBL1 and BIK1."",""doi"":""10.1186/s12870-014-0374-4"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25522736/"",""year"":""2014"",""journal"":""BMC plant biology"",""authors"":""Ranf S; Eschen-Lippold L; Fröhlich K; Westphal L; Scheel D; Lee J"",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""26021844"",""title"":""Regulatory role of BOTRYTIS INDUCED KINASE1 in ETHYLENE INSENSITIVE3-dependent gene expression in Arabidopsis."",""doi"":""10.1007/s00299-015-1812-y"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26021844/"",""year"":""2015"",""journal"":""Plant cell reports"",""authors"":""Kang GH; Son S; Cho YH; Yoo SD"",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""26355215"",""title"":""The Decoy Substrate of a Pathogen Effector and a Pseudokinase Specify Pathogen-Induced Modified-Self Recognition and Immunity in Plants."",""doi"":""10.1016/j.chom.2015.08.004"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26355215/"",""year"":""2015"",""journal"":""Cell host & microbe"",""authors"":""Wang G, Roux B, Feng F, Guy E, Li L, Li N, Zhang X, Lautier M, Jardinaud MF, Chabannes M, Arlat M, Chen S, He C, Noël LD, Zhou JM."",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""30212650"",""title"":""The MAP4 Kinase SIK1 Ensures Robust Extracellular ROS Burst and Antibacterial Immunity in Plants."",""doi"":""10.1016/j.chom.2018.08.007"",""url"":""https://pubmed.ncbi.nlm.nih.gov/30212650/"",""year"":""2018"",""journal"":""Cell host & microbe"",""authors"":""Zhang M, Chiang YH, Toruño TY, Lee D, Ma M, Liang X, Lal NK, Lemos M, Lu YJ, Ma S, Liu J, Day B, Dinesh-Kumar SP, Dehesh K, Dou D, Zhou JM, Coaker G."",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""32404997"",""title"":""Ligand-induced monoubiquitination of BIK1 regulates plant immunity."",""doi"":""10.1038/s41586-020-2210-3"",""url"":""https://pubmed.ncbi.nlm.nih.gov/32404997/"",""year"":""2020"",""journal"":""Nature"",""authors"":""Ma X; Claus LAN; Leslie ME; Tao K; Wu Z; Liu J; Yu X; Li B; Zhou J; Savatin DV; Peng J; Tyler BM; Heese A; Russinova E; He P; Shan L"",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""32846426"",""title"":""The calcium-permeable channel OSCA1.3 regulates plant stomatal immunity."",""doi"":""10.1038/s41586-020-2702-1"",""url"":""https://pubmed.ncbi.nlm.nih.gov/32846426/"",""year"":""2020"",""journal"":""Nature"",""authors"":""Thor K, Jiang S, Michard E, George J, Scherzer S, Huang S, Dindas J, Derbyshire P, Leitão N, DeFalco TA, Köster P, Hunter K, Kimura S, Gronnier J, Stransfeld L, Kadota Y, Bücherl CA, Charpentier M, Wrzaczek M, MacLean D, Oldroyd GED, Menke FLH, Roelfsema MRG, Hedrich R, Feijó J, Zipfel C."",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""34535661"",""title"":""The Arabidopsis MIK2 receptor elicits immunity by sensing a conserved signature from phytocytokines and microbes."",""doi"":""10.1038/s41467-021-25580-w"",""url"":""https://pubmed.ncbi.nlm.nih.gov/34535661/"",""year"":""2021"",""journal"":""Nature communications"",""authors"":""Hou S; Liu D; Huang S; Luo D; Liu Z; Xiang Q; Wang P; Mu R; Han Z; Chen S; Chai J; Shan L; He P"",""matched_aliases"":[""BIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_021933	gene-LXL04_021933	KAL4575092.1	OH-1004	2	Q65XV8	RK176_ORYSJ	Swiss-Prot		Receptor-like cytoplasmic kinase 176 OS=Oryza sativa subsp. japonica OX=39947 GN=RLCK176 PE=1 SV=1	Oryza sativa subsp. japonica	RLCK176	62.785	395	97.65	1.88e-179	507.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os05g0110900	在介导先天免疫的微生物肽聚糖 和真菌几丁质信号通路中的 CERK1 下游发挥作用。	Functions downstream of CERK1 in the microbial peptidoglycans (PGNs) and fungal chitin signaling pathways that mediate innate immunity.	"[{""pmid"":""25335639"",""title"":""OsCERK1 and OsRLCK176 play important roles in peptidoglycan and chitin signaling in rice innate immunity."",""doi"":""10.1111/tpj.12710"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25335639/"",""year"":""2014"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Ao Y, Li Z, Feng D, Xiong F, Liu J, Li JF, Wang M, Wang J, Liu B, Wang HB."",""matched_aliases"":[""OsRLCK176""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"