query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_021930	gene-LXL04_021930	KAL4575089.1	OH-1004	1	Q8VZ79	IDN2_ARATH	Swiss-Prot		Protein INVOLVED IN DE NOVO 2 OS=Arabidopsis thaliana OX=3702 GN=IDN2 PE=1 SV=1	Arabidopsis thaliana	IDN2	51.51	629	56.854	0.0	626.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g48670	与 FDM1/IDNL1 和 FDM2/IDNL2 形成复合物，该复合物对 RNA 定向 DNA 甲基化（RdDM）是必需的，并在 RdDM 通路的下游步骤以及小干扰 RNA（siRNA）形成的下游发挥功能。	Forms a complex with FDM1/IDNL1 and FDM2/IDNL2 that is required for RNA-directed DNA methylation (RdDM) and that functions at a downstream step of the RdDM pathway and downstream of small interfering RNA (siRNA) formation.	"[{""pmid"":""19915591"",""title"":""IDN1 and IDN2 are required for de novo DNA methylation in Arabidopsis thaliana."",""doi"":""10.1038/nsmb.1690"",""url"":""https://pubmed.ncbi.nlm.nih.gov/19915591/"",""year"":""2009"",""journal"":""Nature structural & molecular biology"",""authors"":""Ausin I, Mockler TC, Chory J, Jacobsen SE."",""matched_aliases"":[""IDN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""20059743"",""title"":""An SGS3-like protein functions in RNA-directed DNA methylation and transcriptional gene silencing in Arabidopsis."",""doi"":""10.1111/j.1365-313x.2010.04130.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20059743/"",""year"":""2010"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Zheng Z; Xing Y; He XJ; Li W; Hu Y; Yadav SK; Oh J; Zhu JK"",""matched_aliases"":[""RDM12""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""22570638"",""title"":""IDN2 and its paralogs form a complex required for RNA-directed DNA methylation."",""doi"":""10.1371/journal.pgen.1002693"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22570638/"",""year"":""2012"",""journal"":""PLoS genetics"",""authors"":""Zhang CJ, Ning YQ, Zhang SW, Chen Q, Shao CR, Guo YW, Zhou JX, Li L, Chen S, He XJ."",""matched_aliases"":[""IDN2"",""RDM12""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22592791"",""title"":""INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis."",""doi"":""10.1073/pnas.1206638109"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22592791/"",""year"":""2012"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Ausin I, Greenberg MV, Simanshu DK, Hale CJ, Vashisht AA, Simon SA, Lee TF, Feng S, Española SD, Meyers BC, Wohlschlegel JA, Patel DJ, Jacobsen SE."",""matched_aliases"":[""IDN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22810086"",""title"":""IDN2 has a role downstream of siRNA formation in RNA-directed DNA methylation."",""doi"":""10.4161/epi.21237"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22810086/"",""year"":""2012"",""journal"":""Epigenetics"",""authors"":""Finke A; Kuhlmann M; Mette MF"",""matched_aliases"":[""IDN2"",""RDM12""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""23246435"",""title"":""A SWI/SNF chromatin-remodeling complex acts in noncoding RNA-mediated transcriptional silencing."",""doi"":""10.1016/j.molcel.2012.11.011"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23246435/"",""year"":""2013"",""journal"":""Molecular cell"",""authors"":""Zhu Y; Rowley MJ; Böhmdorfer G; Wierzbicki AT"",""matched_aliases"":[""IDN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""24862207"",""title"":""RNA-directed DNA methylation requires stepwise binding of silencing factors to long non-coding RNA."",""doi"":""10.1111/tpj.12563"",""url"":""https://pubmed.ncbi.nlm.nih.gov/24862207/"",""year"":""2014"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Böhmdorfer G; Rowley MJ; Kuciński J; Zhu Y; Amies I; Wierzbicki AT"",""matched_aliases"":[""IDN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""27171427"",""title"":""Two Components of the RNA-Directed DNA Methylation Pathway Associate with MORC6 and Silence Loci Targeted by MORC6 in Arabidopsis."",""doi"":""10.1371/journal.pgen.1006026"",""url"":""https://pubmed.ncbi.nlm.nih.gov/27171427/"",""year"":""2016"",""journal"":""PLoS genetics"",""authors"":""Liu ZW, Zhou JX, Huang HW, Li YQ, Shao CR, Li L, Cai T, Chen S, He XJ."",""matched_aliases"":[""IDN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_021930	gene-LXL04_021930	KAL4575089.1	OH-1004	3	Q9LHB1	FDM3_ARATH	Swiss-Prot		Factor of DNA methylation 3 OS=Arabidopsis thaliana OX=3702 GN=FDM3 PE=4 SV=1	Arabidopsis thaliana	FDM3	44.849	631	56.302	3.34e-176	533.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g12550	与 FDM4 和 FDM5 关联，参与 RNA 导向的 DNA 甲基化 (RdDM)。	Acts in association with FDM4 and FDM5 for RNA-directed DNA methylation (RdDM).	"[{""pmid"":""22302148"",""title"":""A subgroup of SGS3-like proteins act redundantly in RNA-directed DNA methylation."",""doi"":""10.1093/nar/gks034"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22302148/"",""year"":""2012"",""journal"":""Nucleic acids research"",""authors"":""Xie M, Ren G, Costa-Nunes P, Pontes O, Yu B."",""matched_aliases"":[""FDM3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_021930	gene-LXL04_021930	KAL4575089.1	OH-1004	5	Q9S9P3	FDM1_ARATH	Swiss-Prot		Factor of DNA methylation 1 OS=Arabidopsis thaliana OX=3702 GN=FDM1 PE=1 SV=1	Arabidopsis thaliana	FDM1	37.785	614	55.566	2.97e-131	416.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At1g15910	与 IDN2 和 FDM2/IDNL2 形成复合物，这是 RNA 指导的 DNA 甲基化 所需的，并且在 RdDM 途径的下游步骤发挥作用。	Forms a complex with IDN2 and FDM2/IDNL2 that is required for RNA-directed DNA methylation (RdDM) and that functions at a downstream step of the RdDM pathway.	"[{""pmid"":""22302148"",""title"":""A subgroup of SGS3-like proteins act redundantly in RNA-directed DNA methylation."",""doi"":""10.1093/nar/gks034"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22302148/"",""year"":""2012"",""journal"":""Nucleic acids research"",""authors"":""Xie M, Ren G, Costa-Nunes P, Pontes O, Yu B."",""matched_aliases"":[""FDM1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22570638"",""title"":""IDN2 and its paralogs form a complex required for RNA-directed DNA methylation."",""doi"":""10.1371/journal.pgen.1002693"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22570638/"",""year"":""2012"",""journal"":""PLoS genetics"",""authors"":""Zhang CJ, Ning YQ, Zhang SW, Chen Q, Shao CR, Guo YW, Zhou JX, Li L, Chen S, He XJ."",""matched_aliases"":[""IDP1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22592791"",""title"":""INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis."",""doi"":""10.1073/pnas.1206638109"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22592791/"",""year"":""2012"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Ausin I, Greenberg MV, Simanshu DK, Hale CJ, Vashisht AA, Simon SA, Lee TF, Feng S, Española SD, Meyers BC, Wohlschlegel JA, Patel DJ, Jacobsen SE."",""matched_aliases"":[""IDNL1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_021930	gene-LXL04_021930	KAL4575089.1	OH-1004	7	F4JH53	FDM2_ARATH	Swiss-Prot		Factor of DNA methylation 2 OS=Arabidopsis thaliana OX=3702 GN=FDM2 PE=1 SV=1	Arabidopsis thaliana	FDM2	37.705	610	55.474	4.03e-129	410.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g00380	与 IDN2 和 FDM1/IDNL1 形成复合物，这是 RNA 指导的 DNA 甲基化 所需的，并且在 RdDM 途径的下游步骤发挥作用。	Forms a complex with IDN2 and FDM1/IDNL1 that is required for RNA-directed DNA methylation (RdDM) and that functions at a downstream step of the RdDM pathway.	"[{""pmid"":""22302148"",""title"":""A subgroup of SGS3-like proteins act redundantly in RNA-directed DNA methylation."",""doi"":""10.1093/nar/gks034"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22302148/"",""year"":""2012"",""journal"":""Nucleic acids research"",""authors"":""Xie M, Ren G, Costa-Nunes P, Pontes O, Yu B."",""matched_aliases"":[""FDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22570638"",""title"":""IDN2 and its paralogs form a complex required for RNA-directed DNA methylation."",""doi"":""10.1371/journal.pgen.1002693"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22570638/"",""year"":""2012"",""journal"":""PLoS genetics"",""authors"":""Zhang CJ, Ning YQ, Zhang SW, Chen Q, Shao CR, Guo YW, Zhou JX, Li L, Chen S, He XJ."",""matched_aliases"":[""IDP2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22592791"",""title"":""INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis."",""doi"":""10.1073/pnas.1206638109"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22592791/"",""year"":""2012"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Ausin I, Greenberg MV, Simanshu DK, Hale CJ, Vashisht AA, Simon SA, Lee TF, Feng S, Española SD, Meyers BC, Wohlschlegel JA, Patel DJ, Jacobsen SE."",""matched_aliases"":[""IDNL2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_021930	gene-LXL04_021930	KAL4575089.1	OH-1004	9	Q9SAI1	FDM5_ARATH	Swiss-Prot		Factor of DNA methylation 5 OS=Arabidopsis thaliana OX=3702 GN=FDM5 PE=2 SV=1	Arabidopsis thaliana	FDM5	38.523	623	56.394	2.8e-122	392.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At1g80790	与 FDM3 和 FDM4 联合作用，实现 RNA 指导的 DNA 甲基化。	Acts in association with FDM3 and FDM4 for RNA-directed DNA methylation (RdDM).	"[{""pmid"":""22302148"",""title"":""A subgroup of SGS3-like proteins act redundantly in RNA-directed DNA methylation."",""doi"":""10.1093/nar/gks034"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22302148/"",""year"":""2012"",""journal"":""Nucleic acids research"",""authors"":""Xie M, Ren G, Costa-Nunes P, Pontes O, Yu B."",""matched_aliases"":[""FDM5""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
