TkA08G054950 | RubberDandelionOmics

基因概览

TkA08G054950

当前版本: TK1151 染色体: Chr08 坐标: 14094479-14096744 链方向: + 类型: protein_coding

cDNA / CDS / 蛋白序列

可用序列下载 CDS FASTA 蛋白 FASTA cDNA FASTA

cDNA

1540 bp · TkA08G054950|TK1151|cDNA

TGGAATTAAAAAACTAGAAAAAATGGCTGCAATTCCATTTCCAAACGCGTAATGGTTTTGTCTTTGGCATCTTCTTCCTTGATTTTCCCCTCCATCTCTCCACCCCCAATCCCAGACCCACTTGCTTTTACATAAATCCCAGATTGTCTCTCTCTCTCTCTCTCTCTCTCTGCATTTGCATACATCTTCATATAACCGAGGCAAAGCTGCAATTACTGTGAAAAGTAATGGCGGACGCTAGCGGAGGCTACACTGAGTTT...

CDS

下载 CDS FASTA

624 bp · TkA08G054950|TK1151|CDS

ATGGCGGACGCTAGCGGAGGCTACACTGAGTTTCCGGCGGTGCCGACTCACGGAGGTCAGTTTATCCGCTATAACATCTTCGGTAATGAATTTGAGATCACCAACAAGTATCGTCCTCCAATCATGCCTATTGGTCGTGGTGCTTATGGAATCGTCTGCTCGATGTTGAACTCCGAGACGAACGAGATGGTTGCTGTGAAGAAGATTGCAAATGCTTTCGATAATTACATGGACGCTAAGCGGACGCTTCGCGAGATCAA...

蛋白

下载蛋白 FASTA

207 aa · TkA08G054950|TK1151|PROTEIN

MADASGGYTEFPAVPTHGGQFIRYNIFGNEFEITNKYRPPIMPIGRGAYGIVCSMLNSETNEMVAVKKIANAFDNYMDAKRTLREIKLLRHLDHENIIAIKDIIPPPLRREFSDVYITTELMDTDLHQIIRSNQNLSEEHCQYFLYQLLRGLKYIHSANVIHRDLKPSNLLLNANCDLKICDFGLARTSAENDFMTEYVSNKMVPGP

上下游序列下载

序列方向与下载说明

上游/下游最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

多版本 ID 对照

输入 ID	`TkA08G054950`
TK1151 ID	TkA08G054950
OH-1004 ID	LXL04_018326
关系 / 置信度	跨参考版本对应关系 / 复杂对应关系
蛋白一致性 (%)	86.200
蛋白覆盖度 (%)	TK1151 100.000 / OH-1004 58.734 覆盖度与证据说明覆盖度为最高分比对片段的序列跨度占代表蛋白长度的比例。同源匹配不等同于功能验证。
版本	TK1151 / GWHBCHF00000000

查看完整 ID 对照表

SNP / Indel 变异与样本携带情况CRA009020 · TK1151

展开后加载该基因的变异记录。

基因基本信息与功能注释

基因 ID TkA08G054950

位置 Chr08:14094479-14096744 (+)

描述 Similar to MPK3: Mitogen-activated protein kinase 3

拟南芥 / 水稻参考基因与文献

下载当前基因文献

拟南芥

参考基因 ID	可能功能	对应论文 / DOI
`At3g45640`	参与氧化应激介导的信号级联。	MAP kinase signalling cascade in Arabidopsis innate immunity.2002 · DOI: 10.1038/415977a RNA interference-based (RNAi) suppression of AtMPK6, an Arabidopsis mitogen-activated protein kinase, results in hypersensitivity to ozone and misregulation of AtMPK3.2005 · DOI: 10.1016/j.envpol.2005.04.017 Stomatal development and patterning are regulated by environmentally responsive mitogen-activated protein kinases in Arabidopsis.2007 · DOI: 10.1105/tpc.106.048298 Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling.2008 · DOI: 10.1038/nature06543 A fungal-responsive MAPK cascade regulates phytoalexin biosynthesis in Arabidopsis.2008 · DOI: 10.1073/pnas.0711301105 The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases.2011 · DOI: 10.1111/j.1742-4658.2011.08033.x Arabidopsis MKK4 mediates osmotic-stress response via its regulation of MPK3 activity.2011 · DOI: 10.1016/j.bbrc.2011.07.064 A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation.2012 · DOI: 10.1105/tpc.112.104695 Arabidopsis LIP5, a positive regulator of multivesicular body biogenesis, is a critical target of pathogen-responsive MAPK cascade in plant basal defense.2014 · DOI: 10.1371/journal.ppat.1004243 The BASL polarity protein controls a MAPK signaling feedback loop in asymmetric cell division.2015 · DOI: 10.1016/j.devcel.2015.02.022
`At2g43790`	丝裂原激活蛋白激酶，调节涉及根生长和气孔响应的 MAPKKK20-MKK5-MPK6 级联中的脱落酸反应。	MAP kinase signalling cascade in Arabidopsis innate immunity.2002 · DOI: 10.1038/415977a Silencing of the mitogen-activated protein kinase MPK6 compromises disease resistance in Arabidopsis.2004 · DOI: 10.1105/tpc.015552 The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis.2004 · DOI: 10.1016/j.molcel.2004.06.023 Phosphorylation of 1-aminocyclopropane-1-carboxylic acid synthase by MPK6, a stress-responsive mitogen-activated protein kinase, induces ethylene biosynthesis in Arabidopsis.2004 · DOI: 10.1105/tpc.104.026609 RNA interference-based (RNAi) suppression of AtMPK6, an Arabidopsis mitogen-activated protein kinase, results in hypersensitivity to ozone and misregulation of AtMPK3.2005 · DOI: 10.1016/j.envpol.2005.04.017 Stomatal development and patterning are regulated by environmentally responsive mitogen-activated protein kinases in Arabidopsis.2007 · DOI: 10.1105/tpc.106.048298 The mitogen-activated protein kinase cascade MKK3-MPK6 is an important part of the jasmonate signal transduction pathway in Arabidopsis.2007 · DOI: 10.1105/tpc.106.046581 AtMKK1 mediates ABA-induced CAT1 expression and H2O2 production via AtMPK6-coupled signaling in Arabidopsis.2008 · DOI: 10.1111/j.1365-313x.2008.03433.x Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling.2008 · DOI: 10.1038/nature06543 A fungal-responsive MAPK cascade regulates phytoalexin biosynthesis in Arabidopsis.2008 · DOI: 10.1073/pnas.0711301105 An arabidopsis mitogen-activated protein kinase cascade, MKK9-MPK6, plays a role in leaf senescence.2009 · DOI: 10.1104/pp.108.133439 AtMKK1 and AtMPK6 are involved in abscisic acid and sugar signaling in Arabidopsis seed germination.2009 · DOI: 10.1007/s11103-009-9503-0 The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases.2011 · DOI: 10.1111/j.1742-4658.2011.08033.x A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation.2012 · DOI: 10.1105/tpc.112.104695 Arabidopsis LIP5, a positive regulator of multivesicular body biogenesis, is a critical target of pathogen-responsive MAPK cascade in plant basal defense.2014 · DOI: 10.1371/journal.ppat.1004243 AIK1, A Mitogen-Activated Protein Kinase, Modulates Abscisic Acid Responses through the MKK5-MPK6 Kinase Cascade.2017 · DOI: 10.1104/pp.16.01386

水稻

当前来源表未检出该物种的同源命中。

功能注释来源

查看注释来源

功能注释来源：OH1004 · LXL04_018326 · GCA_047496595.1_OSU_TarKok_2.0。此处为经 ID 对照查得的 OH1004 注释；下方拟南芥/水稻同源表使用当前查询参考的独立蛋白比对。

GO 注释（OH1004 来源）

GO:0006468 protein phosphorylation 生物过程

GO:0006952 defense response 生物过程

GO:0006970 response to osmotic stress 生物过程

GO:0006979 response to oxidative stress 生物过程

GO:0007165 signal transduction 生物过程

GO:0009409 response to cold 生物过程

GO:0009555 pollen development 生物过程

GO:0009611 response to wounding 生物过程

GO:0009617 response to bacterium 生物过程

GO:0009626 plant-type hypersensitive response 生物过程

GO:0009738 abscisic acid-activated signaling pathway 生物过程

GO:0009875 pollen-pistil interaction 生物过程

KEGG 基因交叉引用

ath:AT3G45640

cann:107873437

dosa:Os06g0154500

以下为同源蛋白关联的 KEGG 基因编号，不代表本基因已获得通路功能验证。

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基因表达

查看该基因在不同研究、组织与处理条件下的表达量。表达结果按研究与计量单位分别展示。

查看该基因的表达量

数据来源与对应关系说明

表达数据来自公开转录组研究；参考版本、样本信息和表达单位见查询结果。跨参考版本的对应关系不唯一时，不自动选择表达记录；缺失值不视为表达量为零。

亚细胞定位 Top 5

以下为计算预测或同源注释，不能替代定位实验。

细胞质0.637

排名 1 · TkA08G054950 · TK1151

细胞核0.385

排名 2 · TkA08G054950 · TK1151

细胞膜0.140

排名 3 · TkA08G054950 · TK1151

溶酶体／液泡0.054

排名 4 · TkA08G054950 · TK1151

线粒体0.043

排名 5 · TkA08G054950 · TK1151

LocPro · 直接预测 · 计算预测，非定位实验结果

进入亚细胞定位查询

预测功能结构域

结构域结果来自 Pfam-A/HMMER；位置为对应蛋白序列上的氨基酸坐标。

PF00069Pkinase43-199 aa

PF07714PK_Tyr_Ser-Thr44-197 aa

PF06293Kdo73-179 aa

PF01636APH79-158 aa

PF14531Kinase-like82-98 aa

PF13095FTA285-185 aa

PF01163RIO185-186 aa

PF04281Tom2295-120 aa

基因 ID	结构域编号	结构域名称	起始 aa	终止 aa	E 值	评分
TkA08G054950	`PF00069`	Pkinase	43	199	3.3e-43	148.7
TkA08G054950	`PF07714`	PK_Tyr_Ser-Thr	44	197	5.1e-26	92.3
TkA08G054950	`PF06293`	Kdo	73	179	1e-05	25.8
TkA08G054950	`PF01636`	APH	79	158	0.064	13.7
TkA08G054950	`PF14531`	Kinase-like	82	98	0.11	12.5
TkA08G054950	`PF13095`	FTA2	85	185	0.044	14.1
TkA08G054950	`PF01163`	RIO1	85	186	0.055	13.8
TkA08G054950	`PF04281`	Tom22	95	120	0.15	12.6
TkA08G054950	`PF03109`	ABC1	132	192	0.00024	21.1
TkA08G054950	`PF14531`	Kinase-like	134	184	0.11	12.5
TkA08G054950	`PF01636`	APH	160	186	0.064	13.7
TkA08G054950	`PF12330`	Haspin_kinase	161	193	0.0031	17.3

拟南芥 / 水稻蛋白同源

仅展示拟南芥和水稻；Swiss-Prot 为人工审校条目，TrEMBL 为补充序列候选。同源相似性不等同于实验验证。

下载当前结果

蛋白	物种	描述	一致性	数据库	置信等级
`Q39023`	拟南芥	sp\|Q39023\|MPK3_ARATH Mitogen-activated protein kinase 3	82.600%	Swiss-Prot	高置信
`Q39026`	拟南芥	sp\|Q39026\|MPK6_ARATH Mitogen-activated protein kinase 6	79.100%	Swiss-Prot	高置信

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