query	gene_id	record_type	id	name	namespace_or_position	evidence	source	query_reference	annotation_reference	annotation_gene_id	annotation_assembly	mapping_category	mapped_annotation
TkA04G388530	TkA04G388530	function	TkA04G388530	Similar to IRE1A: Serine/threonine-protein kinase/endoribonuclease IRE1a (Arabidopsis thaliana OX%3D3702)		GFF-derived	GCA_047496595.1_OSU_TarKok_2.0	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=53.883; coverage=42.127; evalue=3.88e-56; UniProt GO evidence=IDA:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0002376	immune system process	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0006351	DNA-templated transcription	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0006397	mRNA processing	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0006914	autophagy	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=53.883; coverage=42.127; evalue=3.88e-56; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0006986	response to unfolded protein	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=57.672; coverage=38.65; evalue=1.36e-57; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0008380	RNA splicing	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0009751	response to salicylic acid	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0030968	endoplasmic reticulum unfolded protein response	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IGI:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0034263	positive regulation of autophagy in response to ER overload	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=53.883; coverage=42.127; evalue=3.88e-56; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0034976	response to endoplasmic reticulum stress	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IEP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0035966	response to topologically incorrect protein	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=31.9; coverage=57.055; evalue=3.82e-31; UniProt GO evidence=IMP:WormBase	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0036498	IRE1-mediated unfolded protein response	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IBA:GO_Central	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0042742	defense response to bacterium	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0045944	positive regulation of transcription by RNA polymerase II	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=31.9; coverage=57.055; evalue=3.82e-31; UniProt GO evidence=IMP:WormBase	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0046777	protein autophosphorylation	biological_process	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IMP:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0005576	extracellular region	cellular_component	Swiss-Prot reviewed homolog transfer; hit_rank=4; identity=40.094; coverage=43.354; evalue=2.51e-32; UniProt GO evidence=ISM:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0005783	endoplasmic reticulum	cellular_component	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IDA:UniProtKB	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0005789	endoplasmic reticulum membrane	cellular_component	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IEA:UniProtKB-SubCell	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0009507	chloroplast	cellular_component	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=ISM:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0099503	secretory vesicle	cellular_component	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=HDA:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0004521	RNA endonuclease activity	molecular_function	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IMP:TAIR	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0004674	protein serine/threonine kinase activity	molecular_function	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IBA:GO_Central	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0005524	ATP binding	molecular_function	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0016787	hydrolase activity	molecular_function	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0046872	metal ion binding	molecular_function	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IEA:UniProtKB-KW	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0051082	unfolded protein binding	molecular_function	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IBA:GO_Central	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	GO	GO:0106310	protein serine kinase activity	molecular_function	Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58; UniProt GO evidence=IEA:RHEA	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	KEGG	ath:AT2G17520	KEGG gene cross-reference from reviewed UniProt hit; pathway name pending		Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=50.237; coverage=43.149; evalue=4.08e-58	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	KEGG	ath:AT3G11870	KEGG gene cross-reference from reviewed UniProt hit; pathway name pending		Swiss-Prot reviewed homolog transfer; hit_rank=4; identity=40.094; coverage=43.354; evalue=2.51e-32	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	KEGG	ath:AT5G24360	KEGG gene cross-reference from reviewed UniProt hit; pathway name pending		Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=53.883; coverage=42.127; evalue=3.88e-56	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	KEGG	cel:CELE_C41C4.4	KEGG gene cross-reference from reviewed UniProt hit; pathway name pending		Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=31.9; coverage=57.055; evalue=3.82e-31	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	KEGG	dosa:Os07g0471000	KEGG gene cross-reference from reviewed UniProt hit; pathway name pending		Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=57.672; coverage=38.65; evalue=1.36e-57	UniProtKB/Swiss-Prot DAT 2026 current_release	TK1151	OH1004	LXL04_038096	GCA_047496595.1_OSU_TarKok_2.0	annotation_conflict	True
TkA04G388530	TkA04G388530	organism_homology	Q93VJ2	sp|Q93VJ2|IRE1B_ARATH Serine/threonine-protein kinase/endoribonuclease IRE1b	Arabidopsis thaliana	identity=44.2; coverage=70.781; evalue=2.9e-113; rank=1	TK1151 Swiss-Prot homology; source_gene=TkA04G388530; source_db=UniProt Swiss-Prot local database (DIAMOND)	TK1151	TK1151	TkA04G388530			False
TkA04G388530	TkA04G388530	organism_homology	Q7XIT1	sp|Q7XIT1|IRE1_ORYSJ Serine/threonine-protein kinase/endoribonuclease IRE1	Oryza sativa subsp. japonica	identity=47.8; coverage=59.062; evalue=1.18e-102; rank=3	TK1151 Swiss-Prot homology; source_gene=TkA04G388530; source_db=UniProt Swiss-Prot local database (DIAMOND)	TK1151	TK1151	TkA04G388530			False
TkA04G388530	TkA04G388530	reference_gene_literature	At5g24360	Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation.	Arabidopsis	Heat induces the splicing by IRE1 of a mRNA encoding a transcription factor involved in the unfolded protein response in Arabidopsis.; PMID=21482766; DOI=10.1073/pnas.1102117108	https://pubmed.ncbi.nlm.nih.gov/21482766/						
TkA04G388530	TkA04G388530	reference_gene_literature	At5g24360	Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation.	Arabidopsis	AtIRE1A/AtIRE1B and AGB1 independently control two essential unfolded protein response pathways in Arabidopsis.; PMID=21914012; DOI=10.1111/j.1365-313x.2011.04788.x	https://pubmed.ncbi.nlm.nih.gov/21914012/						
TkA04G388530	TkA04G388530	reference_gene_literature	At5g24360	Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation.	Arabidopsis	Arabidopsis IRE1 catalyses unconventional splicing of bZIP60 mRNA to produce the active transcription factor.; PMID=22355548; DOI=10.1038/srep00029	https://pubmed.ncbi.nlm.nih.gov/22355548/						
TkA04G388530	TkA04G388530	reference_gene_literature	At5g24360	Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation.	Arabidopsis	IRE1/bZIP60-mediated unfolded protein response plays distinct roles in plant immunity and abiotic stress responses.; PMID=22359644; DOI=10.1371/journal.pone.0031944	https://pubmed.ncbi.nlm.nih.gov/22359644/						
TkA04G388530	TkA04G388530	reference_gene_literature	At5g24360	Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation.	Arabidopsis	Alteration of the bZIP60/IRE1 pathway affects plant response to ER stress in Arabidopsis thaliana.; PMID=22701744; DOI=10.1371/journal.pone.0039023	https://pubmed.ncbi.nlm.nih.gov/22701744/						
TkA04G388530	TkA04G388530	reference_gene_literature	At5g24360	Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation.	Arabidopsis	Degradation of the endoplasmic reticulum by autophagy during endoplasmic reticulum stress in Arabidopsis.; PMID=23175745; DOI=10.1105/tpc.112.101535	https://pubmed.ncbi.nlm.nih.gov/23175745/						
TkA04G388530	TkA04G388530	reference_gene_literature	At2g17520	Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation.	Arabidopsis	Characterization of two homologs of Ire1p, a kinase/endoribonuclease in yeast, in Arabidopsis thaliana.; PMID=12020828; DOI=10.1016/s0167-4781(02)00237-3	https://pubmed.ncbi.nlm.nih.gov/12020828/						
TkA04G388530	TkA04G388530	reference_gene_literature	At2g17520	Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation.	Arabidopsis	AtIRE1A/AtIRE1B and AGB1 independently control two essential unfolded protein response pathways in Arabidopsis.; PMID=21914012; DOI=10.1111/j.1365-313x.2011.04788.x	https://pubmed.ncbi.nlm.nih.gov/21914012/						
TkA04G388530	TkA04G388530	reference_gene_literature	At2g17520	Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation.	Arabidopsis	Arabidopsis IRE1 catalyses unconventional splicing of bZIP60 mRNA to produce the active transcription factor.; PMID=22355548; DOI=10.1038/srep00029	https://pubmed.ncbi.nlm.nih.gov/22355548/						
TkA04G388530	TkA04G388530	reference_gene_literature	At2g17520	Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation.	Arabidopsis	IRE1/bZIP60-mediated unfolded protein response plays distinct roles in plant immunity and abiotic stress responses.; PMID=22359644; DOI=10.1371/journal.pone.0031944	https://pubmed.ncbi.nlm.nih.gov/22359644/						
TkA04G388530	TkA04G388530	reference_gene_literature	Os07g0471000	Involved in endoplasmic reticulum (ER) stress response.	Rice	Signal transduction by IRE1-mediated splicing of bZIP50 and other stress sensors in the endoplasmic reticulum stress response of rice.; PMID=22050533; DOI=10.1111/j.1365-313x.2011.04844.x	https://pubmed.ncbi.nlm.nih.gov/22050533/						
TkA04G388530	TkA04G388530	reference_gene_literature	Os07g0471000	Involved in endoplasmic reticulum (ER) stress response.	Rice	Conservation of IRE1-regulated bZIP74 mRNA unconventional splicing in rice (Oryza sativa L.) involved in ER stress responses.; PMID=22199238; DOI=10.1093/mp/ssr115	https://pubmed.ncbi.nlm.nih.gov/22199238/