query gene_id record_type id name namespace_or_position evidence source query_reference annotation_reference annotation_gene_id annotation_assembly mapping_category mapped_annotation TkA01G409190 TkA01G409190 function TkA01G409190 Similar to HMA2: Cadmium/zinc-transporting ATPase HMA2 (Arabidopsis thaliana OX%3D3702) GFF-derived GCA_047496595.1_OSU_TarKok_2.0 TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0006829 zinc ion transport biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=57.746; coverage=89.308; evalue=0.0; UniProt GO evidence=IMP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0006882 intracellular zinc ion homeostasis biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=52.547; coverage=104.927; evalue=0.0; UniProt GO evidence=IGI:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0010038 response to metal ion biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=57.746; coverage=89.308; evalue=0.0; UniProt GO evidence=IMP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0010043 response to zinc ion biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=57.746; coverage=89.308; evalue=0.0; UniProt GO evidence=IMP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0015691 cadmium ion transport biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=57.746; coverage=89.308; evalue=0.0; UniProt GO evidence=IMP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0030001 metal ion transport biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=57.746; coverage=89.308; evalue=0.0; UniProt GO evidence=IMP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0032025 response to cobalt ion biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=57.746; coverage=89.308; evalue=0.0; UniProt GO evidence=IMP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0046686 response to cadmium ion biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=57.746; coverage=89.308; evalue=0.0; UniProt GO evidence=IMP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0055085 transmembrane transport biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=52.547; coverage=104.927; evalue=0.0; UniProt GO evidence=IBA:GO_Central UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0071585 detoxification of cadmium ion biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=64.017; coverage=72.537; evalue=0.0; UniProt GO evidence=IMP:CACAO UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0005774 vacuolar membrane cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=64.017; coverage=72.537; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-SubCell UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0005886 plasma membrane cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=52.547; coverage=104.927; evalue=0.0; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0009506 plasmodesma cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=57.746; coverage=89.308; evalue=0.0; UniProt GO evidence=HDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0016020 membrane cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=52.547; coverage=104.927; evalue=0.0; UniProt GO evidence=IBA:GO_Central UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0005524 ATP binding molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=52.547; coverage=104.927; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0008551 P-type cadmium transporter activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=52.547; coverage=104.927; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-EC UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0016463 P-type zinc transporter activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=52.547; coverage=104.927; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-EC UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0016887 ATP hydrolysis activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=52.547; coverage=104.927; evalue=0.0; UniProt GO evidence=IEA:InterPro UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0022857 transmembrane transporter activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=52.547; coverage=104.927; evalue=0.0; UniProt GO evidence=IBA:GO_Central UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 GO GO:0046872 metal ion binding molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=52.547; coverage=104.927; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 KEGG ath:AT2G19110 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=57.746; coverage=89.308; evalue=0.0 UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 KEGG ath:AT4G30110 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=52.547; coverage=104.927; evalue=0.0 UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 KEGG dosa:Os06g0700650 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=4; identity=56.577; coverage=90.042; evalue=0.0 UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 KEGG dosa:Os07g0232900 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=56.087; coverage=72.327; evalue=0.0 UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 KEGG osa:4342783 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=56.087; coverage=72.327; evalue=0.0 UniProtKB/Swiss-Prot DAT 2026 current_release TK1151 OH1004 LXL04_002994 GCA_047496595.1_OSU_TarKok_2.0 strict_1to1 True TkA01G409190 TkA01G409190 organism_homology O64474 sp|O64474|HMA4_ARATH Putative cadmium/zinc-transporting ATPase HMA4 Arabidopsis thaliana identity=66.5; coverage=69.483; evalue=0.0; rank=6 TK1151 Swiss-Prot homology; source_gene=TkA01G409190; source_db=UniProt Swiss-Prot local database (DIAMOND) TK1151 TK1151 TkA01G409190 False TkA01G409190 TkA01G409190 organism_homology A3BF39 sp|A3BF39|HMA2_ORYSJ Cadmium/zinc-transporting ATPase HMA2 Oryza sativa subsp. japonica identity=61.0; coverage=73.658; evalue=4.43e-306; rank=9 TK1151 Swiss-Prot homology; source_gene=TkA01G409190; source_db=UniProt Swiss-Prot local database (DIAMOND) TK1151 TK1151 TkA01G409190 False TkA01G409190 TkA01G409190 reference_gene_function At2g19110 参与镉/锌的运输。 Arabidopsis 暂无已核实直接文献 TkA01G409190 TkA01G409190 reference_gene_literature At4g30110 在锌的运输和稳态中起重要作用。 Arabidopsis P-type ATPase heavy metal transporters with roles in essential zinc homeostasis in Arabidopsis.; PMID=15100400; DOI=10.1105/tpc.020487 https://pubmed.ncbi.nlm.nih.gov/15100400/ TkA01G409190 TkA01G409190 reference_gene_function P0CW78 在异源系统中，参与镉和铅的转运，但不参与锌的转运。 Arabidopsis 暂无已核实直接文献 TkA01G409190 TkA01G409190 reference_gene_function At4g30120 推测为失活的镉/锌转运 ATP 酶 HMA3。 Arabidopsis 暂无已核实直接文献 TkA01G409190 TkA01G409190 reference_gene_literature Os06g0700700 锌/镉转运蛋白，在促进锌和镉从根向茎的转运中起关键作用。 Rice Cadmium retention in rice roots is influenced by cadmium availability, chelation and translocation.; PMID=21388416; DOI=10.1111/j.1365-3040.2011.02299.x https://pubmed.ncbi.nlm.nih.gov/21388416/ TkA01G409190 TkA01G409190 reference_gene_literature Os06g0700700 锌/镉转运蛋白，在促进锌和镉从根向茎的转运中起关键作用。 Rice Mutations in rice (Oryza sativa) heavy metal ATPase 2 (OsHMA2) restrict the translocation of zinc and cadmium.; PMID=22123790; DOI=10.1093/pcp/pcr166 https://pubmed.ncbi.nlm.nih.gov/22123790/ TkA01G409190 TkA01G409190 reference_gene_literature Os06g0700700 锌/镉转运蛋白，在促进锌和镉从根向茎的转运中起关键作用。 Rice The OsHMA2 transporter is involved in root-to-shoot translocation of Zn and Cd in rice.; PMID=22548273; DOI=10.1111/j.1365-3040.2012.02527.x https://pubmed.ncbi.nlm.nih.gov/22548273/ TkA01G409190 TkA01G409190 reference_gene_literature Os06g0700700 锌/镉转运蛋白，在促进锌和镉从根向茎的转运中起关键作用。 Rice Preferential delivery of zinc to developing tissues in rice is mediated by P-type heavy metal ATPase OsHMA2.; PMID=23575418; DOI=10.1104/pp.113.216564 https://pubmed.ncbi.nlm.nih.gov/23575418/ TkA01G409190 TkA01G409190 reference_gene_literature Os07g0232900 根特异性镉 (Cd) 转运蛋白，可介导根液泡中的 Cd 外排。 Rice Gene limiting cadmium accumulation in rice.; PMID=20823253; DOI=10.1073/pnas.1005396107 https://pubmed.ncbi.nlm.nih.gov/20823253/ TkA01G409190 TkA01G409190 reference_gene_literature Os07g0232900 根特异性镉 (Cd) 转运蛋白，可介导根液泡中的 Cd 外排。 Rice OsHMA3, a P1B-type of ATPase affects root-to-shoot cadmium translocation in rice by mediating efflux into vacuoles.; PMID=20840506; DOI=10.1111/j.1469-8137.2010.03459.x https://pubmed.ncbi.nlm.nih.gov/20840506/ TkA01G409190 TkA01G409190 reference_gene_literature Os07g0232900 根特异性镉 (Cd) 转运蛋白，可介导根液泡中的 Cd 外排。 Rice Overexpression of OsHMA3 enhances Cd tolerance and expression of Zn transporter genes in rice.; PMID=25151617; DOI=10.1093/jxb/eru340 https://pubmed.ncbi.nlm.nih.gov/25151617/