query gene_id record_type id name namespace_or_position evidence source query_reference annotation_reference annotation_gene_id annotation_assembly mapping_category mapped_annotation LXL04_035944 LXL04_035944 function LXL04_035944 Similar to ATPK2: Serine/threonine-protein kinase AtPK2/AtPK19 (Arabidopsis thaliana OX%3D3702) GFF-derived GCA_047496595.1_OSU_TarKok_2.0 OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0000281 mitotic cytokinesis biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IGI:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0006468 protein phosphorylation biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0006970 response to osmotic stress biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=62.896; coverage=93.843; evalue=0.0; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0007163 establishment or maintenance of cell polarity biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=TAS:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0008285 negative regulation of cell population proliferation biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=62.896; coverage=93.843; evalue=0.0; UniProt GO evidence=IMP:UniProtKB UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0009408 response to heat biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=IEP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0009409 response to cold biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=IEP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0009651 response to salt stress biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=IEP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0030010 establishment of cell polarity biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IGI:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0030011 maintenance of cell polarity biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IMP:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0030334 regulation of cell migration biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IGI:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0031036 myosin II filament assembly biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=TAS:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0031269 pseudopodium assembly biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IMP:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0032060 bleb assembly biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IMP:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0035556 intracellular signal transduction biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IBA:GO_Central UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0042542 response to hydrogen peroxide biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IDA:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0043327 chemotaxis to cAMP biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IGI:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0044351 macropinocytosis biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IMP:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0045727 positive regulation of translation biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=TAS:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0046580 negative regulation of Ras protein signal transduction biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IGI:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0048015 phosphatidylinositol-mediated signaling biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=TAS:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0050765 negative regulation of phagocytosis biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IMP:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0050920 regulation of chemotaxis biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IGI:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0051602 response to electrical stimulus biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IMP:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0071456 cellular response to hypoxia biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=HEP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0090382 phagosome maturation biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IMP:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0110094 polyphosphate-mediated signaling biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IGI:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0140986 G protein-coupled chemorepellent receptor signaling pathway biological_process Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IMP:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:1903013 response to differentiation-inducing factor 1 biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=HDA:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:1904630 cellular response to diterpene biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IGI:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:1905303 positive regulation of macropinocytosis biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IGI:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0005634 nucleus cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0005737 cytoplasm cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=IBA:GO_Central UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0005739 mitochondrion cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=62.896; coverage=93.843; evalue=0.0; UniProt GO evidence=ISM:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0005829 cytosol cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IDA:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0005886 plasma membrane cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IDA:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0005938 cell cortex cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IDA:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0031252 cell leading edge cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IDA:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0004672 protein kinase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=ISS:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0004674 protein serine/threonine kinase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=IBA:GO_Central UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0004691 cAMP-dependent protein kinase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108; UniProt GO evidence=IDA:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0005524 ATP binding molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IDA:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0016301 kinase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0019887 protein kinase regulator activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=TAS:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0030295 protein kinase activator activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IDA:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0031005 filamin binding molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IPI:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0031267 small GTPase binding molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103; UniProt GO evidence=IPI:dictyBase UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 GO GO:0106310 protein serine kinase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0; UniProt GO evidence=IEA:RHEA UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 KEGG ath:AT3G08720 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=63.229; coverage=94.692; evalue=0.0 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 KEGG ath:AT3G08730 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=62.896; coverage=93.843; evalue=0.0 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 KEGG ddi:DDB_G0268620 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=47.975; coverage=68.153; evalue=4.85e-103 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 KEGG ddi:DDB_G0277449 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=4; identity=49.051; coverage=67.091; evalue=2.09e-107 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 KEGG ddi:DDB_G0290157 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=47.262; coverage=73.673; evalue=2.11e-108 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_035944 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_035944 LXL04_035944 organism_homology Q39030 Serine/threonine-protein kinase AtPK2/AtPK19 OS=Arabidopsis thaliana OX=3702 GN=ATPK2 PE=1 SV=2 Arabidopsis thaliana identity=63.229; coverage=89.172; evalue=0.0; rank=1 OH-1004 Swiss-Prot homology; source_gene=LXL04_035944; source_db=UniProt Swiss-Prot current_release 2026-06-10 OH1004 OH1004 LXL04_035944 False LXL04_035944 LXL04_035944 organism_homology_status Oryza sativa 当前查询蛋白的来源表暂无该物种命中；不能据此判断不存在同源。 no_species_hit OH1004 OH1004 LXL04_035944 False LXL04_035944 LXL04_035944 reference_gene_function At3g08720 TOR 信号通路的下游效应器。 Arabidopsis 暂无已核实直接文献 LXL04_035944 LXL04_035944 reference_gene_literature At3g08730 参与渗透应激反应的 TOR 信号通路下游效应器。 Arabidopsis Arabidopsis S6 kinase mutants display chromosome instability and altered RBR1-E2F pathway activity.; PMID=20683442; DOI=10.1038/emboj.2010.164 https://pubmed.ncbi.nlm.nih.gov/20683442/