query gene_id record_type id name namespace_or_position evidence source query_reference annotation_reference annotation_gene_id annotation_assembly mapping_category mapped_annotation LXL04_015261 LXL04_015261 function LXL04_015261 Similar to IRE1B: Serine/threonine-protein kinase/endoribonuclease IRE1b (Arabidopsis thaliana OX%3D3702) GFF-derived GCA_047496595.1_OSU_TarKok_2.0 OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0002376 immune system process biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0006351 DNA-templated transcription biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0006397 mRNA processing biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0006914 autophagy biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0006986 response to unfolded protein biological_process Swiss-Prot reviewed homolog transfer; hit_rank=4; identity=53.896; coverage=54.225; evalue=3.26e-162; UniProt GO evidence=IMP:UniProtKB UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0008380 RNA splicing biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IMP:UniProtKB UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0009751 response to salicylic acid biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IMP:UniProtKB UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0030968 endoplasmic reticulum unfolded protein response biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IGI:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0034263 positive regulation of autophagy in response to ER overload biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IMP:UniProtKB UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0034976 response to endoplasmic reticulum stress biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IEP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0036498 IRE1-mediated unfolded protein response biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IBA:GO_Central UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0042742 defense response to bacterium biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IMP:UniProtKB UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0046777 protein autophosphorylation biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=62.212; coverage=50.939; evalue=0.0; UniProt GO evidence=IMP:UniProtKB UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0005576 extracellular region cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=43.508; coverage=51.526; evalue=4.78e-94; UniProt GO evidence=ISM:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0005783 endoplasmic reticulum cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IDA:UniProtKB UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0005789 endoplasmic reticulum membrane cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-SubCell UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0009507 chloroplast cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=62.212; coverage=50.939; evalue=0.0; UniProt GO evidence=ISM:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0099503 secretory vesicle cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=62.212; coverage=50.939; evalue=0.0; UniProt GO evidence=HDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0004521 RNA endonuclease activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0004674 protein serine/threonine kinase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IBA:GO_Central UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0005524 ATP binding molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0016787 hydrolase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0046872 metal ion binding molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0051082 unfolded protein binding molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IBA:GO_Central UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 GO GO:0106310 protein serine kinase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0; UniProt GO evidence=IEA:RHEA UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 KEGG ath:AT2G17520 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=62.212; coverage=50.939; evalue=0.0 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 KEGG ath:AT3G11870 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=43.508; coverage=51.526; evalue=4.78e-94 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 KEGG ath:AT5G24360 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=45.401; coverage=99.531; evalue=0.0 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 KEGG dosa:Os07g0471000 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=4; identity=53.896; coverage=54.225; evalue=3.26e-162 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_015261 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_015261 LXL04_015261 organism_homology Q93VJ2 Serine/threonine-protein kinase/endoribonuclease IRE1b OS=Arabidopsis thaliana OX=3702 GN=IRE1B PE=2 SV=1 Arabidopsis thaliana identity=45.401; coverage=89.437; evalue=0.0; rank=1 OH-1004 Swiss-Prot homology; source_gene=LXL04_015261; source_db=UniProt Swiss-Prot current_release 2026-06-10 OH1004 OH1004 LXL04_015261 False LXL04_015261 LXL04_015261 organism_homology Q7XIT1 Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Oryza sativa subsp. japonica OX=39947 GN=IRE1 PE=1 SV=1 Oryza sativa subsp. japonica identity=53.896; coverage=53.756; evalue=3.26e-162; rank=4 OH-1004 Swiss-Prot homology; source_gene=LXL04_015261; source_db=UniProt Swiss-Prot current_release 2026-06-10 OH1004 OH1004 LXL04_015261 False LXL04_015261 LXL04_015261 reference_gene_literature At5g24360 Senses 通过其 N 末端结构域在内质网腔中展开蛋白质，从而导致酶自动激活。 Arabidopsis Heat induces the splicing by IRE1 of a mRNA encoding a transcription factor involved in the unfolded protein response in Arabidopsis.; PMID=21482766; DOI=10.1073/pnas.1102117108 https://pubmed.ncbi.nlm.nih.gov/21482766/ LXL04_015261 LXL04_015261 reference_gene_literature At5g24360 Senses 通过其 N 末端结构域在内质网腔中展开蛋白质，从而导致酶自动激活。 Arabidopsis AtIRE1A/AtIRE1B and AGB1 independently control two essential unfolded protein response pathways in Arabidopsis.; PMID=21914012; DOI=10.1111/j.1365-313x.2011.04788.x https://pubmed.ncbi.nlm.nih.gov/21914012/ LXL04_015261 LXL04_015261 reference_gene_literature At5g24360 Senses 通过其 N 末端结构域在内质网腔中展开蛋白质，从而导致酶自动激活。 Arabidopsis Arabidopsis IRE1 catalyses unconventional splicing of bZIP60 mRNA to produce the active transcription factor.; PMID=22355548; DOI=10.1038/srep00029 https://pubmed.ncbi.nlm.nih.gov/22355548/ LXL04_015261 LXL04_015261 reference_gene_literature At5g24360 Senses 通过其 N 末端结构域在内质网腔中展开蛋白质，从而导致酶自动激活。 Arabidopsis IRE1/bZIP60-mediated unfolded protein response plays distinct roles in plant immunity and abiotic stress responses.; PMID=22359644; DOI=10.1371/journal.pone.0031944 https://pubmed.ncbi.nlm.nih.gov/22359644/ LXL04_015261 LXL04_015261 reference_gene_literature At5g24360 Senses 通过其 N 末端结构域在内质网腔中展开蛋白质，从而导致酶自动激活。 Arabidopsis Alteration of the bZIP60/IRE1 pathway affects plant response to ER stress in Arabidopsis thaliana.; PMID=22701744; DOI=10.1371/journal.pone.0039023 https://pubmed.ncbi.nlm.nih.gov/22701744/ LXL04_015261 LXL04_015261 reference_gene_literature At5g24360 Senses 通过其 N 末端结构域在内质网腔中展开蛋白质，从而导致酶自动激活。 Arabidopsis Degradation of the endoplasmic reticulum by autophagy during endoplasmic reticulum stress in Arabidopsis.; PMID=23175745; DOI=10.1105/tpc.112.101535 https://pubmed.ncbi.nlm.nih.gov/23175745/ LXL04_015261 LXL04_015261 reference_gene_literature At2g17520 Senses 通过其 N 末端结构域在内质网腔中展开蛋白质，从而导致酶自动激活。 Arabidopsis Characterization of two homologs of Ire1p, a kinase/endoribonuclease in yeast, in Arabidopsis thaliana.; PMID=12020828; DOI=10.1016/s0167-4781(02)00237-3 https://pubmed.ncbi.nlm.nih.gov/12020828/ LXL04_015261 LXL04_015261 reference_gene_literature At2g17520 Senses 通过其 N 末端结构域在内质网腔中展开蛋白质，从而导致酶自动激活。 Arabidopsis AtIRE1A/AtIRE1B and AGB1 independently control two essential unfolded protein response pathways in Arabidopsis.; PMID=21914012; DOI=10.1111/j.1365-313x.2011.04788.x https://pubmed.ncbi.nlm.nih.gov/21914012/ LXL04_015261 LXL04_015261 reference_gene_literature At2g17520 Senses 通过其 N 末端结构域在内质网腔中展开蛋白质，从而导致酶自动激活。 Arabidopsis Arabidopsis IRE1 catalyses unconventional splicing of bZIP60 mRNA to produce the active transcription factor.; PMID=22355548; DOI=10.1038/srep00029 https://pubmed.ncbi.nlm.nih.gov/22355548/ LXL04_015261 LXL04_015261 reference_gene_literature At2g17520 Senses 通过其 N 末端结构域在内质网腔中展开蛋白质，从而导致酶自动激活。 Arabidopsis IRE1/bZIP60-mediated unfolded protein response plays distinct roles in plant immunity and abiotic stress responses.; PMID=22359644; DOI=10.1371/journal.pone.0031944 https://pubmed.ncbi.nlm.nih.gov/22359644/ LXL04_015261 LXL04_015261 reference_gene_function At3g11870 失活的丝氨酸／苏氨酸蛋白激酶／核糖核酸内切酶IRE1样蛋白。 Arabidopsis 暂无已核实直接文献 LXL04_015261 LXL04_015261 reference_gene_literature Os07g0471000 参与内质网 应激反应。 Rice Signal transduction by IRE1-mediated splicing of bZIP50 and other stress sensors in the endoplasmic reticulum stress response of rice.; PMID=22050533; DOI=10.1111/j.1365-313x.2011.04844.x https://pubmed.ncbi.nlm.nih.gov/22050533/ LXL04_015261 LXL04_015261 reference_gene_literature Os07g0471000 参与内质网 应激反应。 Rice Conservation of IRE1-regulated bZIP74 mRNA unconventional splicing in rice (Oryza sativa L.) involved in ER stress responses.; PMID=22199238; DOI=10.1093/mp/ssr115 https://pubmed.ncbi.nlm.nih.gov/22199238/