query gene_id record_type id name namespace_or_position evidence source query_reference annotation_reference annotation_gene_id annotation_assembly mapping_category mapped_annotation LXL04_002378 LXL04_002378 function LXL04_002378 Similar to MKK2: Mitogen-activated protein kinase kinase 2 (Arabidopsis thaliana OX%3D3702) GFF-derived GCA_047496595.1_OSU_TarKok_2.0 OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0000165 MAPK cascade biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IC:TIGR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0002229 defense response to oomycetes biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IGI:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0002237 response to molecule of bacterial origin biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=64.789; coverage=100.282; evalue=7.67e-168; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0006952 defense response biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=83.333; coverage=100.0; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0007165 signal transduction biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=83.333; coverage=100.0; evalue=0.0; UniProt GO evidence=IBA:GO_Central UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0009409 response to cold biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IDA:UniProtKB UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0009414 response to water deprivation biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=64.789; coverage=100.282; evalue=7.67e-168; UniProt GO evidence=IMP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0009611 response to wounding biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=64.789; coverage=100.282; evalue=7.67e-168; UniProt GO evidence=IEP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0009612 response to mechanical stimulus biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0009631 cold acclimation biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IDA:UniProtKB UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0009651 response to salt stress biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0009875 pollen-pistil interaction biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IGI:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0010051 xylem and phloem pattern formation biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IMP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0010200 response to chitin biological_process Swiss-Prot reviewed homolog transfer; hit_rank=4; identity=59.706; coverage=96.045; evalue=2.54e-157; UniProt GO evidence=IMP:UniProtKB UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0042542 response to hydrogen peroxide biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=64.789; coverage=100.282; evalue=7.67e-168; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0042742 defense response to bacterium biological_process Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=64.789; coverage=100.282; evalue=7.67e-168; UniProt GO evidence=IDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0045087 innate immune response biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0051707 response to other organism biological_process Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=83.333; coverage=100.0; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-ARBA UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0060918 auxin transport biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IMP:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0098542 defense response to other organism biological_process Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IGI:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0005634 nucleus cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=64.789; coverage=100.282; evalue=7.67e-168; UniProt GO evidence=ISM:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0005737 cytoplasm cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=HDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0005886 plasma membrane cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=HDA:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0009507 chloroplast cellular_component Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=64.789; coverage=100.282; evalue=7.67e-168; UniProt GO evidence=ISM:TAIR UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0004674 protein serine/threonine kinase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=83.333; coverage=100.0; evalue=0.0; UniProt GO evidence=IBA:GO_Central UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0004708 MAP kinase kinase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=83.333; coverage=100.0; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-EC UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0004713 protein tyrosine kinase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IEA:RHEA UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0005524 ATP binding molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=83.333; coverage=100.0; evalue=0.0; UniProt GO evidence=IEA:UniProtKB-KW UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 GO GO:0106310 protein serine kinase activity molecular_function Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0; UniProt GO evidence=IEA:RHEA UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 KEGG ath:AT4G26070 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=3; identity=64.789; coverage=100.282; evalue=7.67e-168 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 KEGG ath:AT4G29810 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=2; identity=68.362; coverage=100.0; evalue=0.0 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 KEGG dosa:Os01g0510100 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=5; identity=59.76; coverage=94.068; evalue=3.05e-152 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 KEGG nta:107818847 KEGG gene cross-reference from reviewed UniProt hit; pathway name pending Swiss-Prot reviewed homolog transfer; hit_rank=1; identity=83.333; coverage=100.0; evalue=0.0 UniProtKB/Swiss-Prot DAT 2026 current_release OH1004 OH1004 LXL04_002378 GCA_047496595.1_OSU_TarKok_2.0 False LXL04_002378 LXL04_002378 organism_homology Q9S7U9 Mitogen-activated protein kinase kinase 2 OS=Arabidopsis thaliana OX=3702 GN=MKK2 PE=1 SV=2 Arabidopsis thaliana identity=68.362; coverage=100.0; evalue=0.0; rank=2 OH-1004 Swiss-Prot homology; source_gene=LXL04_002378; source_db=UniProt Swiss-Prot current_release 2026-06-10 OH1004 OH1004 LXL04_002378 False LXL04_002378 LXL04_002378 organism_homology Q5QN75 Mitogen-activated protein kinase kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=MKK1 PE=1 SV=1 Oryza sativa subsp. japonica identity=59.76; coverage=93.503; evalue=3.05e-152; rank=5 OH-1004 Swiss-Prot homology; source_gene=LXL04_002378; source_db=UniProt Swiss-Prot current_release 2026-06-10 OH1004 OH1004 LXL04_002378 False LXL04_002378 LXL04_002378 reference_gene_literature At4g29810 MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Arabidopsis The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis.; PMID=15225555; DOI=10.1016/j.molcel.2004.06.023 https://pubmed.ncbi.nlm.nih.gov/15225555/ LXL04_002378 LXL04_002378 reference_gene_literature At4g29810 MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Arabidopsis The MAP kinase kinase MKK2 affects disease resistance in Arabidopsis.; PMID=17506336; DOI=10.1094/mpmi-20-5-0589 https://pubmed.ncbi.nlm.nih.gov/17506336/ LXL04_002378 LXL04_002378 reference_gene_literature At4g29810 MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Arabidopsis Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1.; PMID=18599650; DOI=10.1104/pp.108.120006 https://pubmed.ncbi.nlm.nih.gov/18599650/ LXL04_002378 LXL04_002378 reference_gene_literature At4g26070 MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Arabidopsis ATMPK4, an Arabidopsis homolog of mitogen-activated protein kinase, is activated in vitro by AtMEK1 through threonine phosphorylation.; PMID=10759527; DOI=10.1104/pp.122.4.1301 https://pubmed.ncbi.nlm.nih.gov/10759527/ LXL04_002378 LXL04_002378 reference_gene_literature At4g26070 MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Arabidopsis The Arabidopsis MAP kinase kinase MKK1 participates in defence responses to the bacterial elicitor flagellin.; PMID=17059410; DOI=10.1111/j.1365-313x.2006.02888.x https://pubmed.ncbi.nlm.nih.gov/17059410/ LXL04_002378 LXL04_002378 reference_gene_literature At4g26070 MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Arabidopsis AtMEK1 mediates stress-induced gene expression of CAT1 catalase by triggering H2O2 production in Arabidopsis.; PMID=17728292; DOI=10.1093/jxb/erm144 https://pubmed.ncbi.nlm.nih.gov/17728292/ LXL04_002378 LXL04_002378 reference_gene_literature At4g26070 MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Arabidopsis AtMKK1 mediates ABA-induced CAT1 expression and H2O2 production via AtMPK6-coupled signaling in Arabidopsis.; PMID=18248592; DOI=10.1111/j.1365-313x.2008.03433.x https://pubmed.ncbi.nlm.nih.gov/18248592/ LXL04_002378 LXL04_002378 reference_gene_literature At4g26070 MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Arabidopsis Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1.; PMID=18599650; DOI=10.1104/pp.108.120006 https://pubmed.ncbi.nlm.nih.gov/18599650/ LXL04_002378 LXL04_002378 reference_gene_literature At4g26070 MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Arabidopsis AtMKK1 and AtMPK6 are involved in abscisic acid and sugar signaling in Arabidopsis seed germination.; PMID=19484493; DOI=10.1007/s11103-009-9503-0 https://pubmed.ncbi.nlm.nih.gov/19484493/ LXL04_002378 LXL04_002378 reference_gene_function Os01g0510100 Mitogen-activated protein kinase kinase 1. Rice No verified direct reference in this release