物种	参考基因 ID	可能功能	对应论文 / DOI
拟南芥	At2g36490	双功能 DNA 糖基化酶/裂解酶，可切除 5-甲基胞嘧啶 (5-meC) 和 5-羟甲基胞嘧啶 (5-hmeC)，留下一个嘧啶缺失 (AP) 位点，随后由裂解酶活性切割。	ROS1, a repressor of transcriptional gene silencing in Arabidopsis, encodes a DNA glycosylase/lyase.; 2002; DOI: 10.1016/s0092-8674(02)01133-9; PMID: 12526807; https://pubmed.ncbi.nlm.nih.gov/12526807/ | DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases.; 2006; DOI: 10.1073/pnas.0601109103; PMID: 16624880; https://pubmed.ncbi.nlm.nih.gov/16624880/ | ROS1 5-methylcytosine DNA glycosylase is a slow-turnover catalyst that initiates DNA demethylation in a distributive fashion.; 2009; DOI: 10.1093/nar/gkp390; PMID: 19443451; https://pubmed.ncbi.nlm.nih.gov/19443451/ | Methylation-independent DNA binding modulates specificity of Repressor of Silencing 1 (ROS1) and facilitates demethylation in long substrates.; 2010; DOI: 10.1074/jbc.m110.124578; PMID: 20489198; https://pubmed.ncbi.nlm.nih.gov/20489198/ | DDM1 and ROS1 have a role in UV-B induced- and oxidative DNA damage in A. thaliana.; 2013; DOI: 10.3389/fpls.2013.00420; PMID: 24155752; https://pubmed.ncbi.nlm.nih.gov/24155752/ | AP endonucleases process 5-methylcytosine excision intermediates during active DNA demethylation in Arabidopsis.; 2014; DOI: 10.1093/nar/gku834; PMID: 25228464; https://pubmed.ncbi.nlm.nih.gov/25228464/ | The carboxy-terminal domain of ROS1 is essential for 5-methylcytosine DNA glycosylase activity.; 2014; DOI: 10.1016/j.jmb.2014.09.010; PMID: 25240767; https://pubmed.ncbi.nlm.nih.gov/25240767/
拟南芥	UniProt: Q8LK56	参与基因印记的转录激活因子。	暂无已核实直接文献
拟南芥	At3g10010	潜在的转录激活因子，可能通过切割目标启动子发挥作用。	暂无已核实直接文献
水稻	Os01g0218032	双功能DNA糖基化酶/裂解酶，可切除5-甲基胞嘧啶 (5-meC) 和5-羟甲基胞嘧啶 (5-hmeC)，产生一个嘧啶缺位(AP)位点，随后该位点由裂解酶活性切开（可能）。	A null mutation of ROS1a for DNA demethylation in rice is not transmittable to progeny.; 2012; DOI: 10.1111/j.1365-313x.2012.05009.x; PMID: 22448681; https://pubmed.ncbi.nlm.nih.gov/22448681/ | Mutations in the DNA demethylase OsROS1 result in a thickened aleurone and improved nutritional value in rice grains.; 2018; DOI: 10.1073/pnas.1806304115; PMID: 30275307; https://pubmed.ncbi.nlm.nih.gov/30275307/
水稻	Os05g0445900	双功能 DNA 糖基化酶/裂解酶，可切除 5-甲基胞嘧啶 (5-meC) 和 5-羟甲基胞嘧啶 (5-hmeC)，留下一个嘧啶缺失 (AP) 位点，随后由裂解酶活性切割。	A 5-methylcytosine DNA glycosylase/lyase demethylates the retrotransposon Tos17 and promotes its transposition in rice.; 2011; DOI: 10.1073/pnas.1112704108; PMID: 21896764; https://pubmed.ncbi.nlm.nih.gov/21896764/