Species	Reference gene ID	Possible function	Papers / DOI
Arabidopsis	At4g26080	Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), drought-induced resistance and rhizogenesis, response to glucose, high light stress, seed germination and inhibition of vegetative growth.	Arabidopsis abi1-1 and abi2-1 phosphatase mutations reduce abscisic acid-induced cytoplasmic calcium rises in guard cells.; 1999; DOI: 10.1105/tpc.11.9.1785; PMID: 10488243; https://pubmed.ncbi.nlm.nih.gov/10488243/ | ABI1 protein phosphatase 2C is a negative regulator of abscisic acid signaling.; 1999; DOI: 10.1105/tpc.11.10.1897; PMID: 10521520; https://pubmed.ncbi.nlm.nih.gov/10521520/ | The role of ABI1 in abscisic acid signal transduction: from gene to cell.; 1998; PMID: 10645425; https://pubmed.ncbi.nlm.nih.gov/10645425/ | The genes ABI1 and ABI2 are involved in abscisic acid- and drought-inducible expression of the Daucus carota L. Dc3 promoter in guard cells of transgenic Arabidopsis thaliana (L.) Heynh.; 2000; DOI: 10.1007/s004250050692; PMID: 10872217; https://pubmed.ncbi.nlm.nih.gov/10872217/ | Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar.; 2000; PMID: 10950871; https://pubmed.ncbi.nlm.nih.gov/10950871/ | The ABI1 and ABI2 protein phosphatases 2C act in a negative feedback regulatory loop of the abscisic acid signalling pathway.; 2001; DOI: 10.1046/j.1365-313x.2001.00965.x; PMID: 11208021; https://pubmed.ncbi.nlm.nih.gov/11208021/ | Cortical actin filaments in guard cells respond differently to abscisic acid in wild-type and abi1-1 mutant Arabidopsis.; 2001; DOI: 10.1007/s004250000489; PMID: 11289613; https://pubmed.ncbi.nlm.nih.gov/11289613/ | Dissection of abscisic acid signal transduction pathways in barley aleurone layers.; 2001; DOI: 10.1023/a:1011667312754; PMID: 11587514; https://pubmed.ncbi.nlm.nih.gov/11587514/ | Abscisic acid activation of plasma membrane Ca(2+) channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in abi1-1 and abi2-1 protein phosphatase 2C mutants.; 2001; DOI: 10.1105/tpc.010210; PMID: 11701885; https://pubmed.ncbi.nlm.nih.gov/11701885/ | The role of ABA and the transpiration stream in the regulation of the osmotic water permeability of leaf cells.; 2001; DOI: 10.1073/pnas.231471998; PMID: 11707572; https://pubmed.ncbi.nlm.nih.gov/11707572/ | Use of infrared thermal imaging to isolate Arabidopsis mutants defective in stomatal regulation.; 2002; DOI: 10.1046/j.1365-313x.2002.01322.x; PMID: 12047634; https://pubmed.ncbi.nlm.nih.gov/12047634/ | Homeodomain protein ATHB6 is a target of the protein phosphatase ABI1 and regulates hormone responses in Arabidopsis.; 2002; DOI: 10.1093/emboj/cdf316; PMID: 12065416; https://pubmed.ncbi.nlm.nih.gov/12065416/ | A calcium sensor and its interacting protein kinase are global regulators of abscisic acid signaling in Arabidopsis.; 2002; DOI: 10.1016/s1534-5807(02)00229-0; PMID: 12194854; https://pubmed.ncbi.nlm.nih.gov/12194854/ | Role of Abscisic Acid in Drought-Induced Freezing Tolerance, Cold Acclimation, and Accumulation of LT178 and RAB18 Proteins in Arabidopsis thaliana.; 1995; DOI: 10.1104/pp.107.1.141; PMID: 12228349; https://pubmed.ncbi.nlm.nih.gov/12228349/ | Drought Rhizogenesis in Arabidopsis thaliana (Differential Responses of Hormonal Mutants).; 1994; DOI: 10.1104/pp.104.2.761; PMID: 12232124; https://pubmed.ncbi.nlm.nih.gov/12232124/ | Maternal Effects Govern Variable Dominance of Two Abscisic Acid Response Mutations in Arabidopsis thaliana.; 1994; DOI: 10.1104/pp.105.4.1203; PMID: 12232276; https://pubmed.ncbi.nlm.nih.gov/12232276/ | Genome-wide gene expression profiling in Arabidopsis thaliana reveals new targets of abscisic acid and largely impaired gene regulation in the abi1-1 mutant.; 2002; DOI: 10.1242/jcs.00175; PMID: 12432076; https://pubmed.ncbi.nlm.nih.gov/12432076/ | Control of Ascorbate Peroxidase 2 expression by hydrogen peroxide and leaf water status during excess light stress reveals a functional organisation of Arabidopsis leaves.; 2003; DOI: 10.1046/j.1365-313x.2003.01656.x; PMID: 12609042; https://pubmed.ncbi.nlm.nih.gov/12609042/ | The abi1-1 mutation blocks ABA signaling downstream of cADPR action.; 2003; DOI: 10.1046/j.1365-313x.2003.01721.x; PMID: 12713537; https://pubmed.ncbi.nlm.nih.gov/12713537/ | Synthesis of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is concertedly regulated by metabolic and stress-associated signals.; 2003; DOI: 10.1104/pp.103.026294; PMID: 14576281; https://pubmed.ncbi.nlm.nih.gov/14576281/ | Regulation of the ABA-sensitive Arabidopsis potassium channel gene GORK in response to water stress.; 2003; DOI: 10.1016/s0014-5793(03)01118-9; PMID: 14596925; https://pubmed.ncbi.nlm.nih.gov/14596925/ | Phospholipase D alpha 1-derived phosphatidic acid interacts with ABI1 phosphatase 2C and regulates abscisic acid signaling.; 2004; DOI: 10.1073/pnas.0402112101; PMID: 15197253; https://pubmed.ncbi.nlm.nih.gov/15197253/ | Generation of active pools of abscisic acid revealed by in vivo imaging of water-stressed Arabidopsis.; 2005; DOI: 10.1104/pp.104.053082; PMID: 15618419; https://pubmed.ncbi.nlm.nih.gov/15618419/ | Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance.; 2005; DOI: 10.1104/pp.105.062257; PMID: 15923322; https://pubmed.ncbi.nlm.nih.gov/15923322/ | Role of abscisic acid (ABA) and Arabidopsis thaliana ABA-insensitive loci in low water potential-induced ABA and proline accumulation.; 2006; DOI: 10.1093/jxb/erj026; PMID: 16339784; https://pubmed.ncbi.nlm.nih.gov/16339784/ | The regulatory domain of SRK2E/OST1/SnRK2.6 interacts with ABI1 and integrates abscisic acid (ABA) and osmotic stress signals controlling stomatal closure in Arabidopsis.; 2006; DOI: 10.1074/jbc.m509820200; PMID: 16365038; https://pubmed.ncbi.nlm.nih.gov/16365038/ | Fibrillin expression is regulated by abscisic acid response regulators and is involved in abscisic acid-mediated photoprotection.; 2006; DOI: 10.1073/pnas.0501720103; PMID: 16571665; https://pubmed.ncbi.nlm.nih.gov/16571665/ | A bifurcating pathway directs abscisic acid effects on stomatal closure and opening in Arabidopsis.; 2006; DOI: 10.1126/science.1123769; PMID: 16614222; https://pubmed.ncbi.nlm.nih.gov/16614222/ | Abscisic Acid Elicits the Water-Stress Response in Root Hairs of Arabidopsis thaliana.; 1992; DOI: 10.1104/pp.100.1.216; PMID: 16652949; https://pubmed.ncbi.nlm.nih.gov/16652949/ | Enhancement of abscisic acid sensitivity and reduction of water consumption in Arabidopsis by combined inactivation of the protein phosphatases type 2C ABI1 and HAB1.; 2006; DOI: 10.1104/pp.106.081018; PMID: 16798945; https://pubmed.ncbi.nlm.nih.gov/16798945/ | Abscisic acid antagonizes ethylene-induced hyponastic growth in Arabidopsis.; 2007; DOI: 10.1104/pp.106.092700; PMID: 17158582; https://pubmed.ncbi.nlm.nih.gov/17158582/ | Pseudomonas syringae pv. tomato hijacks the Arabidopsis abscisic acid signalling pathway to cause disease.; 2007; DOI: 10.1038/sj.emboj.7601575; PMID: 17304219; https://pubmed.ncbi.nlm.nih.gov/17304219/ | Nuclear localization of the mutant protein phosphatase abi1 is required for insensitivity towards ABA responses in Arabidopsis.; 2008; DOI: 10.1111/j.1365-313x.2008.03454.x; PMID: 18298671; https://pubmed.ncbi.nlm.nih.gov/18298671/ | Cold acclimation and cold-regulated gene expression in ABA mutants of Arabidopsis thaliana.; 1991; DOI: 10.1007/bf00028738; PMID: 1834244; https://pubmed.ncbi.nlm.nih.gov/1834244/ | ABI1 and PP2CA phosphatases are negative regulators of Snf1-related protein kinase1 signaling in Arabidopsis.; 2013; DOI: 10.1105/tpc.113.114066; PMID: 24179127; https://pubmed.ncbi.nlm.nih.gov/24179127/ | Arabidopsis ABA-Activated Kinase MAPKKK18 is Regulated by Protein Phosphatase 2C ABI1 and the Ubiquitin-Proteasome Pathway.; 2015; DOI: 10.1093/pcp/pcv146; PMID: 26443375; https://pubmed.ncbi.nlm.nih.gov/26443375/ | AIK1, A Mitogen-Activated Protein Kinase, Modulates Abscisic Acid Responses through the MKK5-MPK6 Kinase Cascade.; 2017; DOI: 10.1104/pp.16.01386; PMID: 27913741; https://pubmed.ncbi.nlm.nih.gov/27913741/ | Sensitivity to abscisic acid of guard-cell K+ channels is suppressed by abi1-1, a mutant Arabidopsis gene encoding a putative protein phosphatase.; 1995; DOI: 10.1073/pnas.92.21.9520; PMID: 7568166; https://pubmed.ncbi.nlm.nih.gov/7568166/ | Abscisic acid-insensitive mutations provide evidence for stage-specific signal pathways regulating expression of an Arabidopsis late embryogenesis-abundant (lea) gene.; 1993; DOI: 10.1007/bf00291999; PMID: 8492808; https://pubmed.ncbi.nlm.nih.gov/8492808/ | The Arabidopsis homeobox gene ATHB-7 is induced by water deficit and by abscisic acid.; 1996; DOI: 10.1046/j.1365-313x.1996.10020375.x; PMID: 8771791; https://pubmed.ncbi.nlm.nih.gov/8771791/ | Protein phosphatase activity of abscisic acid insensitive 1 (ABI1) protein from Arabidopsis thaliana.; 1996; DOI: 10.1111/j.1432-1033.1996.0193t.x; PMID: 8898906; https://pubmed.ncbi.nlm.nih.gov/8898906/ | Differential abscisic acid regulation of guard cell slow anion channels in Arabidopsis wild-type and abi1 and abi2 mutants.; 1997; DOI: 10.1105/tpc.9.3.409; PMID: 9090884; https://pubmed.ncbi.nlm.nih.gov/9090884/ | Abscisic acid-independent and abscisic acid-dependent regulation of proline biosynthesis following cold and osmotic stresses in Arabidopsis thaliana.; 1997; DOI: 10.1007/s004380050397; PMID: 9108297; https://pubmed.ncbi.nlm.nih.gov/9108297/ | Interactions between the ABI1 and the ectopically expressed ABI3 genes in controlling abscisic acid responses in Arabidopsis vegetative tissues.; 1997; DOI: 10.1046/j.1365-313x.1997.11040693.x; PMID: 9161030; https://pubmed.ncbi.nlm.nih.gov/9161030/ | The Arabidopsis ABSCISIC ACID-INSENSITIVE2 (ABI2) and ABI1 genes encode homologous protein phosphatases 2C involved in abscisic acid signal transduction.; 1997; DOI: 10.1105/tpc.9.5.759; PMID: 9165752; https://pubmed.ncbi.nlm.nih.gov/9165752/ | Alteration of anion channel kinetics in wild-type and abi1-1 transgenic Nicotiana benthamiana guard cells by abscisic acid.; 1997; DOI: 10.1046/j.1365-313x.1997.12010203.x; PMID: 9263461; https://pubmed.ncbi.nlm.nih.gov/9263461/ | Convergence of the abscisic acid, CO2, and extracellular calcium signal transduction pathways in stomatal guard cells.; 1997; DOI: 10.1104/pp.114.4.1557; PMID: 9276963; https://pubmed.ncbi.nlm.nih.gov/9276963/ | Differential expression of two P5CS genes controlling proline accumulation during salt-stress requires ABA and is regulated by ABA1, ABI1 and AXR2 in Arabidopsis.; 1997; DOI: 10.1046/j.1365-313x.1997.00557.x; PMID: 9351242; https://pubmed.ncbi.nlm.nih.gov/9351242/ | Mutational analysis of protein phosphatase 2C involved in abscisic acid signal transduction in higher plants.; 1998; DOI: 10.1073/pnas.95.3.975; PMID: 9448270; https://pubmed.ncbi.nlm.nih.gov/9448270/
Arabidopsis	At5g57050	Repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), high light stress, response to glucose, seed germination and inhibition of vegetative growth.	Arabidopsis abi1-1 and abi2-1 phosphatase mutations reduce abscisic acid-induced cytoplasmic calcium rises in guard cells.; 1999; DOI: 10.1105/tpc.11.9.1785; PMID: 10488243; https://pubmed.ncbi.nlm.nih.gov/10488243/ | The genes ABI1 and ABI2 are involved in abscisic acid- and drought-inducible expression of the Daucus carota L. Dc3 promoter in guard cells of transgenic Arabidopsis thaliana (L.) Heynh.; 2000; DOI: 10.1007/s004250050692; PMID: 10872217; https://pubmed.ncbi.nlm.nih.gov/10872217/ | Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar.; 2000; PMID: 10950871; https://pubmed.ncbi.nlm.nih.gov/10950871/ | The ABI1 and ABI2 protein phosphatases 2C act in a negative feedback regulatory loop of the abscisic acid signalling pathway.; 2001; DOI: 10.1046/j.1365-313x.2001.00965.x; PMID: 11208021; https://pubmed.ncbi.nlm.nih.gov/11208021/ | Abscisic acid activation of plasma membrane Ca(2+) channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in abi1-1 and abi2-1 protein phosphatase 2C mutants.; 2001; DOI: 10.1105/tpc.010210; PMID: 11701885; https://pubmed.ncbi.nlm.nih.gov/11701885/ | The role of ABA and the transpiration stream in the regulation of the osmotic water permeability of leaf cells.; 2001; DOI: 10.1073/pnas.231471998; PMID: 11707572; https://pubmed.ncbi.nlm.nih.gov/11707572/ | Hypersensitivity of abscisic acid-induced cytosolic calcium increases in the Arabidopsis farnesyltransferase mutant era1-2.; 2002; DOI: 10.1105/tpc.010448; PMID: 12119381; https://pubmed.ncbi.nlm.nih.gov/12119381/ | A calcium sensor and its interacting protein kinase are global regulators of abscisic acid signaling in Arabidopsis.; 2002; DOI: 10.1016/s1534-5807(02)00229-0; PMID: 12194854; https://pubmed.ncbi.nlm.nih.gov/12194854/ | Maternal Effects Govern Variable Dominance of Two Abscisic Acid Response Mutations in Arabidopsis thaliana.; 1994; DOI: 10.1104/pp.105.4.1203; PMID: 12232276; https://pubmed.ncbi.nlm.nih.gov/12232276/ | Hydrotropism in abscisic acid, wavy, and gravitropic mutants of Arabidopsis thaliana.; 2002; DOI: 10.1007/s00425-002-0840-3; PMID: 12447533; https://pubmed.ncbi.nlm.nih.gov/12447533/ | Control of Ascorbate Peroxidase 2 expression by hydrogen peroxide and leaf water status during excess light stress reveals a functional organisation of Arabidopsis leaves.; 2003; DOI: 10.1046/j.1365-313x.2003.01656.x; PMID: 12609042; https://pubmed.ncbi.nlm.nih.gov/12609042/ | Synthesis of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is concertedly regulated by metabolic and stress-associated signals.; 2003; DOI: 10.1104/pp.103.026294; PMID: 14576281; https://pubmed.ncbi.nlm.nih.gov/14576281/ | Regulation of the ABA-sensitive Arabidopsis potassium channel gene GORK in response to water stress.; 2003; DOI: 10.1016/s0014-5793(03)01118-9; PMID: 14596925; https://pubmed.ncbi.nlm.nih.gov/14596925/ | The ABI2-dependent abscisic acid signalling controls HrpN-induced drought tolerance in Arabidopsis.; 2005; DOI: 10.1007/s00425-004-1444-x; PMID: 15599761; https://pubmed.ncbi.nlm.nih.gov/15599761/ | Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance.; 2005; DOI: 10.1104/pp.105.062257; PMID: 15923322; https://pubmed.ncbi.nlm.nih.gov/15923322/ | Role of abscisic acid (ABA) and Arabidopsis thaliana ABA-insensitive loci in low water potential-induced ABA and proline accumulation.; 2006; DOI: 10.1093/jxb/erj026; PMID: 16339784; https://pubmed.ncbi.nlm.nih.gov/16339784/ | Fibrillin expression is regulated by abscisic acid response regulators and is involved in abscisic acid-mediated photoprotection.; 2006; DOI: 10.1073/pnas.0501720103; PMID: 16571665; https://pubmed.ncbi.nlm.nih.gov/16571665/ | Interaction between sugar and abscisic acid signalling during early seedling development in Arabidopsis.; 2008; DOI: 10.1007/s11103-008-9308-6; PMID: 18278579; https://pubmed.ncbi.nlm.nih.gov/18278579/ | A plasma membrane receptor kinase, GHR1, mediates abscisic acid- and hydrogen peroxide-regulated stomatal movement in Arabidopsis.; 2012; DOI: 10.1105/tpc.112.100107; PMID: 22730405; https://pubmed.ncbi.nlm.nih.gov/22730405/ | Abscisic acid induces the alcohol dehydrogenase gene in Arabidopsis.; 1996; DOI: 10.1104/pp.111.2.381; PMID: 8787023; https://pubmed.ncbi.nlm.nih.gov/8787023/ | Differential abscisic acid regulation of guard cell slow anion channels in Arabidopsis wild-type and abi1 and abi2 mutants.; 1997; DOI: 10.1105/tpc.9.3.409; PMID: 9090884; https://pubmed.ncbi.nlm.nih.gov/9090884/ | Abscisic acid-independent and abscisic acid-dependent regulation of proline biosynthesis following cold and osmotic stresses in Arabidopsis thaliana.; 1997; DOI: 10.1007/s004380050397; PMID: 9108297; https://pubmed.ncbi.nlm.nih.gov/9108297/ | The Arabidopsis ABSCISIC ACID-INSENSITIVE2 (ABI2) and ABI1 genes encode homologous protein phosphatases 2C involved in abscisic acid signal transduction.; 1997; DOI: 10.1105/tpc.9.5.759; PMID: 9165752; https://pubmed.ncbi.nlm.nih.gov/9165752/ | Convergence of the abscisic acid, CO2, and extracellular calcium signal transduction pathways in stomatal guard cells.; 1997; DOI: 10.1104/pp.114.4.1557; PMID: 9276963; https://pubmed.ncbi.nlm.nih.gov/9276963/
Arabidopsis	At1g72770	Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth.	Gain-of-function and loss-of-function phenotypes of the protein phosphatase 2C HAB1 reveal its role as a negative regulator of abscisic acid signalling.; 2004; DOI: 10.1046/j.1365-313x.2003.01966.x; PMID: 14731256; https://pubmed.ncbi.nlm.nih.gov/14731256/ | Enhancement of abscisic acid sensitivity and reduction of water consumption in Arabidopsis by combined inactivation of the protein phosphatases type 2C ABI1 and HAB1.; 2006; DOI: 10.1104/pp.106.081018; PMID: 16798945; https://pubmed.ncbi.nlm.nih.gov/16798945/ | A hypermorphic mutation in the protein phosphatase 2C HAB1 strongly affects ABA signaling in Arabidopsis.; 2006; DOI: 10.1016/j.febslet.2006.07.047; PMID: 16876791; https://pubmed.ncbi.nlm.nih.gov/16876791/
Rice	Os01g0583100	Probable protein phosphatase that may function in abscisic acid (ABA) signaling.	No verified direct reference in this release
Rice	Os05g0592800	Protein phosphatase that acts as a negative regulator of abscisic acid (ABA) signaling.	ABA Regulates Subcellular Redistribution of OsABI-LIKE2, a Negative Regulator in ABA Signaling, to Control Root Architecture and Drought Resistance in Oryza sativa.; 2015; DOI: 10.1093/pcp/pcv154; PMID: 26491145; https://pubmed.ncbi.nlm.nih.gov/26491145/