Species	Reference gene ID	Possible function	Papers / DOI
Arabidopsis	At1g73500	MKK9-MPK3/MPK6 module phosphorylates and activates EIN3, leading to the promotion of EIN3-mediated transcription in ethylene signaling.	Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling.; 2008; DOI: 10.1038/nature06543; PMID: 18273012; https://pubmed.ncbi.nlm.nih.gov/18273012/ | Activation of MAPK kinase 9 induces ethylene and camalexin biosynthesis and enhances sensitivity to salt stress in Arabidopsis.; 2008; DOI: 10.1074/jbc.m801392200; PMID: 18693252; https://pubmed.ncbi.nlm.nih.gov/18693252/ | An arabidopsis mitogen-activated protein kinase cascade, MKK9-MPK6, plays a role in leaf senescence.; 2009; DOI: 10.1104/pp.108.133439; PMID: 19251906; https://pubmed.ncbi.nlm.nih.gov/19251906/
Arabidopsis	At1g18350	May function as a negative regulator of polar auxin transport.	Increased expression of MAP KINASE KINASE7 causes deficiency in polar auxin transport and leads to plant architectural abnormality in Arabidopsis.; 2006; DOI: 10.1105/tpc.105.037846; PMID: 16377756; https://pubmed.ncbi.nlm.nih.gov/16377756/ | Overexpression of Arabidopsis MAP kinase kinase 7 leads to activation of plant basal and systemic acquired resistance.; 2007; DOI: 10.1111/j.1365-313x.2007.03294.x; PMID: 17908155; https://pubmed.ncbi.nlm.nih.gov/17908155/
Arabidopsis	At3g06230	Mitogen-activated protein kinase kinase 8.	No verified direct reference in this release
Arabidopsis	At3g21220	Mitogen-activated protein kinase kinase (MAPKK) which regulates abscisic acid (ABA) responses in a MAPKKK20-MKK5-MPK6 cascade involved in root growth (e.g. root cell division and elongation) and stomatal response, probably via MAPK6 activation by protein phosphorylation.	Cell death mediated by MAPK is associated with hydrogen peroxide production in Arabidopsis.; 2002; DOI: 10.1074/jbc.m109495200; PMID: 11687590; https://pubmed.ncbi.nlm.nih.gov/11687590/ | MAP kinase signalling cascade in Arabidopsis innate immunity.; 2002; DOI: 10.1038/415977a; PMID: 11875555; https://pubmed.ncbi.nlm.nih.gov/11875555/ | Stomatal development and patterning are regulated by environmentally responsive mitogen-activated protein kinases in Arabidopsis.; 2007; DOI: 10.1105/tpc.106.048298; PMID: 17259259; https://pubmed.ncbi.nlm.nih.gov/17259259/ | Ethylene signaling is required for the acceleration of cell death induced by the activation of AtMEK5 in Arabidopsis.; 2008; DOI: 10.1038/cr.2008.29; PMID: 18268539; https://pubmed.ncbi.nlm.nih.gov/18268539/ | Regulation of floral organ abscission in Arabidopsis thaliana.; 2008; DOI: 10.1073/pnas.0805539105; PMID: 18809915; https://pubmed.ncbi.nlm.nih.gov/18809915/ | A Pseudomonas syringae ADP-ribosyltransferase inhibits Arabidopsis mitogen-activated protein kinase kinases.; 2010; DOI: 10.1105/tpc.110.075697; PMID: 20571112; https://pubmed.ncbi.nlm.nih.gov/20571112/ | A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation.; 2012; DOI: 10.1105/tpc.112.104695; PMID: 23263767; https://pubmed.ncbi.nlm.nih.gov/23263767/ | Brassinosteroid-regulated GSK3/Shaggy-like kinases phosphorylate mitogen-activated protein (MAP) kinase kinases, which control stomata development in Arabidopsis thaliana.; 2013; DOI: 10.1074/jbc.m112.384453; PMID: 23341468; https://pubmed.ncbi.nlm.nih.gov/23341468/ | MKK5 regulates high light-induced gene expression of Cu/Zn superoxide dismutase 1 and 2 in Arabidopsis.; 2013; DOI: 10.1093/pcp/pct072; PMID: 23677921; https://pubmed.ncbi.nlm.nih.gov/23677921/ | Identification of BZR1-interacting proteins as potential components of the brassinosteroid signaling pathway in Arabidopsis through tandem affinity purification.; 2013; DOI: 10.1074/mcp.m113.029256; PMID: 24019147; https://pubmed.ncbi.nlm.nih.gov/24019147/ | AIK1, A Mitogen-Activated Protein Kinase, Modulates Abscisic Acid Responses through the MKK5-MPK6 Kinase Cascade.; 2017; DOI: 10.1104/pp.16.01386; PMID: 27913741; https://pubmed.ncbi.nlm.nih.gov/27913741/
Arabidopsis	At1g51660	Involved in the second phase of hydrogen peroxide generation during hypersensitive response-like cell death.	MAP kinase signalling cascade in Arabidopsis innate immunity.; 2002; DOI: 10.1038/415977a; PMID: 11875555; https://pubmed.ncbi.nlm.nih.gov/11875555/ | Stomatal development and patterning are regulated by environmentally responsive mitogen-activated protein kinases in Arabidopsis.; 2007; DOI: 10.1105/tpc.106.048298; PMID: 17259259; https://pubmed.ncbi.nlm.nih.gov/17259259/ | Regulation of floral organ abscission in Arabidopsis thaliana.; 2008; DOI: 10.1073/pnas.0805539105; PMID: 18809915; https://pubmed.ncbi.nlm.nih.gov/18809915/ | Arabidopsis MKK4 mediates osmotic-stress response via its regulation of MPK3 activity.; 2011; DOI: 10.1016/j.bbrc.2011.07.064; PMID: 21806969; https://pubmed.ncbi.nlm.nih.gov/21806969/ | A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation.; 2012; DOI: 10.1105/tpc.112.104695; PMID: 23263767; https://pubmed.ncbi.nlm.nih.gov/23263767/ | Brassinosteroid-regulated GSK3/Shaggy-like kinases phosphorylate mitogen-activated protein (MAP) kinase kinases, which control stomata development in Arabidopsis thaliana.; 2013; DOI: 10.1074/jbc.m112.384453; PMID: 23341468; https://pubmed.ncbi.nlm.nih.gov/23341468/