﻿Species	Reference gene ID	Possible function	Papers / DOI
Arabidopsis	At3g48080	Acts as a second functional copy of EDS1.	No verified direct reference in this release
Arabidopsis	At3g48090	Positive regulator of basal resistance and of effector-triggered immunity specifically mediated by TIR-NB-LRR (TNL) resistance proteins.	EDS1, an essential component of R gene-mediated disease resistance in Arabidopsis has homology to eukaryotic lipases.; 1999; DOI: 10.1073/pnas.96.6.3292; PMID: 10077677; https://pubmed.ncbi.nlm.nih.gov/10077677/ | Direct interaction between the Arabidopsis disease resistance signaling proteins, EDS1 and PAD4.; 2001; DOI: 10.1093/emboj/20.19.5400; PMID: 11574472; https://pubmed.ncbi.nlm.nih.gov/11574472/ | Arabidopsis SENESCENCE-ASSOCIATED GENE101 stabilizes and signals within an ENHANCED DISEASE SUSCEPTIBILITY1 complex in plant innate immunity.; 2005; DOI: 10.1105/tpc.105.033910; PMID: 16040633; https://pubmed.ncbi.nlm.nih.gov/16040633/ | Balanced nuclear and cytoplasmic activities of EDS1 are required for a complete plant innate immune response.; 2010; DOI: 10.1371/journal.ppat.1000970; PMID: 20617163; https://pubmed.ncbi.nlm.nih.gov/20617163/ | Different roles of Enhanced Disease Susceptibility1 (EDS1) bound to and dissociated from Phytoalexin Deficient4 (PAD4) in Arabidopsis immunity.; 2011; DOI: 10.1111/j.1469-8137.2011.03675.x; PMID: 21434927; https://pubmed.ncbi.nlm.nih.gov/21434927/ | Pathogen effectors target Arabidopsis EDS1 and alter its interactions with immune regulators.; 2011; DOI: 10.1126/science.1211592; PMID: 22158819; https://pubmed.ncbi.nlm.nih.gov/22158819/ | EDS1 contributes to nonhost resistance of Arabidopsis thaliana against Erwinia amylovora.; 2012; DOI: 10.1094/mpmi-05-11-0111; PMID: 22316300; https://pubmed.ncbi.nlm.nih.gov/22316300/ | Contrasting Roles of the Apoplastic Aspartyl Protease APOPLASTIC, ENHANCED DISEASE SUSCEPTIBILITY1-DEPENDENT1 and LEGUME LECTIN-LIKE PROTEIN1 in Arabidopsis Systemic Acquired Resistance.; 2014; DOI: 10.1104/pp.114.239665; PMID: 24755512; https://pubmed.ncbi.nlm.nih.gov/24755512/
Arabidopsis	UniProt: Q9XF23	Positive regulator of basal resistance and of effector-triggered immunity specifically mediated by TIR-NB-LRR resistance proteins.	No verified direct reference in this release
